Coxiella burnetii Effector Proteins That Localize to the Parasitophorous Vacuole Membrane Promote Intracellular Replication

Identification of Novel Coxiella burnetii Icm/Dot Effectors and Genetic Analysis of Their Involvement in Modulating a Mitogen-Activated Protein Kinase Pathway

(2014) Ziv Lifshitz et al.   INFECTION AND IMMUNITY

The structure of the N-terminal domain of the Legionella protein SidC

(2014) Emerich Mihai Gazdag et al.   JOURNAL OF STRUCTURAL BIOLOGY

AMPylation Is Critical for Rab1 Localization to Vacuoles Containing Legionella pneumophila

(2014) C. A. Hardiman et al.   mBio

Identification of OmpA, a Coxiella burnetii Protein Involved in Host Cell Invasion, by Multi-Phenotypic High-Content Screening

(2014) Eric Martinez et al.   PLoS Pathogens

A Screen of Coxiella burnetii Mutants Reveals Important Roles for Dot/Icm Effectors and Host Autophagy in Vacuole Biogenesis

(2014) Hayley J. Newton et al.   PLoS Pathogens

Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP

(2013) Qin Yu et al.   CELL RESEARCH

Identification of Coxiella burnetii Type IV Secretion Substrates Required for Intracellular Replication and Coxiella-Containing Vacuole Formation

(2013) M. M. Weber et al.   JOURNAL OF BACTERIOLOGY

Refining the Plasmid-Encoded Type IV Secretion System Substrate Repertoire of Coxiella burnetii

(2013) P. Maturana et al.   JOURNAL OF BACTERIOLOGY

The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism

(2013) Ashwini K. Mishra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii

(2013) Erin J. van Schaik et al.   NATURE REVIEWS MICROBIOLOGY

Effector Protein Translocation by the Coxiella burnetii Dot/Icm Type IV Secretion System Requires Endocytic Maturation of the Pathogen-Occupied Vacuole

(2013) Hayley J. Newton et al.   PLoS One

LegC3, an Effector Protein from Legionella pneumophila, Inhibits Homotypic Yeast Vacuole Fusion In Vivo and In Vitro

(2013) Terry L. Bennett et al.   PLoS One

Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal

(2013) Z. Lifshitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coxiella burnetii effector protein subverts clathrin-mediated vesicular trafficking for pathogen vacuole biogenesis

(2013) C. L. Larson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host Pathways Important for Coxiella burnetii Infection Revealed by Genome-Wide RNA Interference Screening

(2013) J. A. McDonough et al.   mBio

The Serine Phosphatase SerB of Porphyromonas gingivalis Suppresses IL-8 Production by Dephosphorylation of NF-κB RelA/p65

(2013) Hiroki Takeuchi et al.   PLoS Pathogens

Two Systems for Targeted Gene Deletion in Coxiella burnetii

(2012) Paul A. Beare et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Endocytic SNAREs are involved in optimalCoxiella burnetiivacuole development

(2012) Emanuel Martín Campoy et al.   CELLULAR MICROBIOLOGY

Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State

(2012) Wei Cheng et al.   PLoS Pathogens

Isolation from Animal Tissue and Genetic Transformation of Coxiella burnetii Are Facilitated by an Improved Axenic Growth Medium

(2011) Anders Omsland et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Coxiella burnetii Cryptic Plasmid Is Enriched in Genes Encoding Type IV Secretion System Substrates

(2011) D. E. Voth et al.   JOURNAL OF BACTERIOLOGY

Subversion of membrane transport pathways by vacuolar pathogens

(2011) Eric Alix et al.   JOURNAL OF CELL BIOLOGY

Dot/Icm Type IVB Secretion System Requirements for Coxiella burnetii Growth in Human Macrophages

(2011) P. A. Beare et al.   mBio

The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication

(2011) Kimberly L. Carey et al.   PLoS Pathogens

The E Block motif is associated with Legionella pneumophila translocated substrates

(2010) Li Huang et al.   CELLULAR MICROBIOLOGY

Coxiella burnetii Phase I and II Variants Replicate with Similar Kinetics in Degradative Phagolysosome-Like Compartments of Human Macrophages

(2010) D. Howe et al.   INFECTION AND IMMUNITY

The Early Secretory Pathway Contributes to the Growth of theCoxiella-Replicative Niche

(2010) Emanuel Martín Campoy et al.   INFECTION AND IMMUNITY

Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii

(2010) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

SNARE motif: A common motif used by pathogens to manipulate membrane fusion

(2010) Jordan Wesolowski et al.   Virulence

Effector protein modulation of host cells: examples in the Chlamydia spp. arsenal

(2009) Helen J Betts et al.   CURRENT OPINION IN MICROBIOLOGY

The Coxiella burnetii Ankyrin Repeat Domain-Containing Protein Family Is Heterogeneous, with C-Terminal Truncations That Influence Dot/Icm-Mediated Secretion

(2009) D. E. Voth et al.   JOURNAL OF BACTERIOLOGY

Intracellular Bacteria Encode Inhibitory SNARE-Like Proteins

(2009) Fabienne Paumet et al.   PLoS One

Genome-Scale Identification of Legionella pneumophila Effectors Using a Machine Learning Approach

(2009) David Burstein et al.   PLoS Pathogens

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

Comparative Genomics Reveal Extensive Transposon-Mediated Genomic Plasticity and Diversity among Potential Effector Proteins within the Genus Coxiella

(2008) P. A. Beare et al.   INFECTION AND IMMUNITY

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ankyrin Repeat Proteins Comprise a Diverse Family of Bacterial Type IV Effectors

(2008) X. Pan et al.   SCIENCE

Legionella Eukaryotic-Like Type IV Substrates Interfere with Organelle Trafficking

(2008) Karim Suwwan de Felipe et al.   PLoS Pathogens