The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism

Structural Basis Unifying Diverse GTP Hydrolysis Mechanisms

(2013) Baskaran Anand et al.   BIOCHEMISTRY

Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP

(2013) Qin Yu et al.   CELL RESEARCH

Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB

(2013) Emerich Mihai Gazdag et al.   EMBO REPORTS

Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses

(2012) Na Dong et al.   CELL

The Legionella pneumophila Effector DrrA Is Sufficient to Stimulate SNARE-Dependent Membrane Fusion

(2012) Kohei Arasaki et al.   Cell Host & Microbe

Reversible phosphocholination of Rab proteins byLegionella pneumophilaeffector proteins

(2012) Philip R Goody et al.   EMBO JOURNAL

Legionella pneumophila LidA Affects Nucleotide Binding and Activity of the Host GTPase Rab1

(2012) M. R. Neunuebel et al.   JOURNAL OF BACTERIOLOGY

Characterization of Enzymes fromLegionella pneumophilaInvolved in Reversible Adenylylation of Rab1 Protein

(2012) Matthias P. Müller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations

(2012) T. Rudack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catalytic mechanism of a mammalian Rab{middle dot}RabGAP complex in atomic detail

(2012) K. Gavriljuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploitation of evolutionarily conserved amoeba and mammalian processes by Legionella

(2012) Tasneem Al-Quadan et al.   TRENDS IN MICROBIOLOGY

Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State

(2012) Wei Cheng et al.   PLoS Pathogens

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila

(2011) Wenhan Zhu et al.   PLoS One

Protein LidA from Legionella is a Rab GTPase supereffector

(2011) S. Schoebel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Stabilizing a Weak Binding State for Effectors in the Human Ras Protein by Cyclen Complexes

(2010) Ina C. Rosnizeck et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rab GEFs and GAPs

(2010) Francis Barr et al.   CURRENT OPINION IN CELL BIOLOGY

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

Legionella pneumophila Promotes Functional Interactions between Plasma Membrane Syntaxins and Sec22b

(2010) Kohei Arasaki et al.   TRAFFIC

Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA

(2009) Hye-Young Suh et al.   EMBO JOURNAL

RabGDI Displacement by DrrA from Legionella Is a Consequence of Its Guanine Nucleotide Exchange Activity

(2009) Stefan Schoebel et al.   MOLECULAR CELL

Structural Mechanisms for Regulation of Membrane Traffic by Rab GTPases

(2009) Meng-Tse Gabe Lee et al.   TRAFFIC

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY