Chemokine axis as a therapeutic target to enhance the recruitment of Tregs and treat organ-specific autoimmune and inflammatory diseases

A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens

(2011) H. Pere et al.   BLOOD

Tregs in immunotherapy: opportunities and challenges

(2011) WanJun Chen   Immunotherapy

Complex interplays in immune T-cell differentiation and developmental fate determination

(2011) Huynh Thien Duc   Immunotherapy

Cell therapy to promote transplantation tolerance: a winning strategy?

(2011) Giovanna Lombardi et al.   Immunotherapy

Inhibition of differentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin

(2011) Mohan S. Maddur et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets

(2011) Joel Montane et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXP3+ regulatory T cells: control of FOXP3 expression by pharmacological agents

(2011) Naganari Ohkura et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Regulatory T cells as potential targets for immunotherapy in inflammatory bowel disease

(2010) Caterina Strisciuglio et al.   Immunotherapy

Combination therapies for Type 1 diabetes: why not now?

(2010) Matthias von Herrath   Immunotherapy

Human T-Lymphotropic Virus Type 1-Induced CC Chemokine Ligand 22 Maintains a High Frequency of Functional FoxP3+ Regulatory T Cells

(2010) F. Toulza et al.   JOURNAL OF IMMUNOLOGY

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Surveillance of Antigen-Presenting Cells by CD4+CD25+ Regulatory T Cells in Autoimmunity

(2009) Sébastien André et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

(2009) M. Gobert et al.   CANCER RESEARCH

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Targeted knock down of CCL22 and CCL17 by siRNA during DC differentiation and maturation affects the recruitment of T subsets

(2009) Shijun Kang et al.   IMMUNOBIOLOGY

Immunotherapy with regulatory T cells in transplantation

(2009) Jorieke H Peters et al.   Immunotherapy

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

CTLA-4: a key protein in autoimmunity

(2009) Jagadeesh Bayry   Nature Reviews Rheumatology

Toward the Discovery of Vaccine Adjuvants: Coupling In Silico Screening and In Vitro Analysis of Antagonist Binding to Human and Mouse CCR4 Receptors

(2009) Matthew N. Davies et al.   PLoS One

Novel cellular and molecular mechanisms of induction of immune responses by aluminum adjuvants

(2009) Vishukumar Aimanianda et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

(2008) Qizhi Tang et al.   NATURE IMMUNOLOGY

In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination

(2008) J. Bayry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis

(2007) A. Ephrem et al.   BLOOD