CCR6 and CCL20: emerging players in the pathogenesis of rheumatoid arthritis

CCR6 Regulates the Migration of Inflammatory and Regulatory T Cells

(2014) T. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

Targeting Interleukin-6 in Rheumatoid Arthritis

(2013) Md Yuzaiful Md Yusof et al.   DRUGS

CC Chemokine Ligand 20 and Its Cognate Receptor CCR6 in Mucosal T Cell Immunology and Inflammatory Bowel Disease: Odd Couple or Axis of Evil?

(2013) Adrian Y. S. Lee et al.   Frontiers in Immunology

Chemokine receptor CCR1 antagonist CCX354-C treatment for rheumatoid arthritis: CARAT-2, a randomised, placebo controlled clinical trial

(2012) Paul P Tak et al.   ANNALS OF THE RHEUMATIC DISEASES

Th17 cells are restrained by Treg cells via the inhibition of interleukin-6 in patients with rheumatoid arthritis responding to anti-tumor necrosis factor antibody therapy

(2012) Jenny L. McGovern et al.   ARTHRITIS AND RHEUMATISM

A Single-nucleotide Polymorphism of CCR6 (rs3093024) Is Associated with Susceptibility to Rheumatoid Arthritis But Not Ankylosing Spondylitis, in a Taiwanese Population: Table 1.

(2012) WEI-CHIAO CHANG et al.   JOURNAL OF RHEUMATOLOGY

Preferential Accumulation of Activated Th1 Cells Not Only in Rheumatoid Arthritis But Also in Osteoarthritis Joints

(2011) H. YAMADA et al.   JOURNAL OF RHEUMATOLOGY

CCL20 Stimulates Proinflammatory Mediator Synthesis in Human Fibroblast-like Synoviocytes Through a MAP Kinase-dependent Process with Transcriptional and Posttranscriptional Control

(2011) N. ALAAEDDINE et al.   JOURNAL OF RHEUMATOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

(2010) J. P. van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans

(2010) Laura B. Hughes et al.   ARTHRITIS AND RHEUMATISM

Th-17 associated cytokines in patients with reactive arthritis/undifferentiated spondyloarthropathy

(2010) Amit Kumar Singh et al.   CLINICAL RHEUMATOLOGY

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

(2010) Yuta Kochi et al.   NATURE GENETICS

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Evidence for a cross-talk between human neutrophils and Th17 cells

(2009) M. Pelletier et al.   BLOOD

CCL20 produced in the cytokine network of rheumatoid arthritis recruits CCR6+ mononuclear cells and enhances the production of IL-6

(2009) Shimei Tanida et al.   CYTOKINE

CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: Different response of osteoblasts in the two groups

(2009) Gina Lisignoli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IL-17 Induces Monocyte Migration in Rheumatoid Arthritis

(2009) S. Shahrara et al.   JOURNAL OF IMMUNOLOGY

Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis

(2009) Erin G. Harper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Proinflammatory Cytokines Synergistically Enhance the Production of Chemokine Ligand 20 (CCL20) from Rheumatoid Fibroblast-like Synovial Cells in vitro and Serum CCL20 Is Reduced in vivo by Biologic Disease-modifying Antirheumatic Drugs

(2009) S.-Y. KAWASHIRI et al.   JOURNAL OF RHEUMATOLOGY

The Treg/Th17 Cell Balance: A New Paradigm for Autoimmunity

(2009) Eli M Eisenstein et al.   PEDIATRIC RESEARCH

Serum amyloid A protein stimulates CCL20 production in rheumatoid synoviocytes

(2009) K. Migita et al.   RHEUMATOLOGY

Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis

(2009) Toshihiro Nanki et al.   ARTHRITIS RESEARCH & THERAPY

Chemokines and leukocyte traffic

(2008) Federica Sallusto et al.   NATURE IMMUNOLOGY

TH-17 cells in rheumatoid arthritis

(2008) Shiva Shahrara et al.   ARTHRITIS RESEARCH & THERAPY