The bullseye synapse formed between CD4+ T-cell and staphylococcal enterotoxin B-pulsed dendritic cell is a suppressive synapse in T-cell response

T Cell-Dendritic Cell Immunological Synapses Contain TCR-dependent CD28-CD80 Clusters That Recruit Protein Kinase C 

(2014) S.-Y. Tseng et al.   JOURNAL OF IMMUNOLOGY

Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse

(2013) Helena Soares et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multimolecular Analysis of Stable Immunological Synapses Reveals Sustained Recruitment and Sequential Assembly of Signaling Clusters

(2013) Lars Philipsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Integration of the movement of signaling microclusters with cellular motility in immunological synapses

(2012) Peter Beemiller et al.   NATURE IMMUNOLOGY

ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance

(2011) Bin Qu et al.   CELL CALCIUM

PKC-θ function at the immunological synapse: prospects for therapeutic targeting

(2011) Alexandra Zanin-Zhorov et al.   TRENDS IN IMMUNOLOGY

Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock

(2011) Gila Arad et al.   PLOS BIOLOGY

Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics

(2010) Rachel S. Friedman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Anergic CD4+ T Cells Form Mature Immunological Synapses with Enhanced Accumulation of c-Cbl and Cbl-b

(2010) M. Doherty et al.   JOURNAL OF IMMUNOLOGY

T Cell Polarity at the Immunological Synapse Is Required for CD154-Dependent IL-12 Secretion by Dendritic Cells

(2010) M. Tourret et al.   JOURNAL OF IMMUNOLOGY

Protein Kinase C-  Mediates Negative Feedback on Regulatory T Cell Function

(2010) A. Zanin-Zhorov et al.   SCIENCE

The immunological synapse controls local and global calcium signals in T lymphocytes

(2009) Carsten Kummerow et al.   IMMUNOLOGICAL REVIEWS

Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry

(2009) Markus Thiel et al.   IMMUNOLOGY

Dendritic cell microvilli: a novel membrane structure associated with the multifocal synapse and T-cell clustering

(2008) P. J. Fisher et al.   BLOOD

Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters and Protein Kinase C θ Translocation

(2008) Tadashi Yokosuka et al.   IMMUNITY

CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization

(2007) Helga Schneider et al.   EUROPEAN JOURNAL OF IMMUNOLOGY