Human T follicular helper (Tfh) cells and disease

IL-12 receptor  1 deficiency alters in vivo T follicular helper cell response in humans

(2013) N. Schmitt et al.   BLOOD

Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia

(2013) Matthew J. Ahearne et al.   BRITISH JOURNAL OF HAEMATOLOGY

Follicular helper T cells may play an important role in the severity of primary Sjögren's syndrome

(2013) Krisztina Szabo et al.   CLINICAL IMMUNOLOGY

Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

(2013) Michela Locci et al.   IMMUNITY

Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency

(2013) Fabienne Mazerolles et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CD4+ follicular helper T cell infiltration predicts breast cancer survival

(2013) Chunyan Gu-Trantien et al.   JOURNAL OF CLINICAL INVESTIGATION

Expansion of circulating counterparts of follicular helper T cells in patients with myasthenia gravis

(2013) Chuanming Luo et al.   JOURNAL OF NEUROIMMUNOLOGY

Peripheral T-cell and NK-cell lymphomas in the WHO classification: pearls and pitfalls

(2013) Elaine S Jaffe et al.   MODERN PATHOLOGY

Inadequate T follicular cell help impairs B cell immunity during HIV infection

(2013) Rafael A Cubas et al.   NATURE MEDICINE

Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

(2013) Jeppe Romme Christensen et al.   PLoS One

STAT3 Signaling Induces the Differentiation of Human ICOS+ CD4 T Cells Helping B lymphocytes

(2013) Laure Ysebrant de Lendonck et al.   PLoS One

Clinicopathologic Analysis of Peripheral T-Cell Lymphoma, Follicular Variant, and Comparison With Angioimmunoblastic T-Cell Lymphoma

(2012) Hiroaki Miyoshi et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Role of the frequency of blood CD4+ CXCR5+ CCR6+ T cells in autoimmunity in patients with Sjögren’s syndrome

(2012) Xue-yi Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine

(2012) S. Pallikkuth et al.   BLOOD

Functional STAT3 deficiency compromises the generation of human T follicular helper cells

(2012) C. S. Ma et al.   BLOOD

The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

(2012) Aron Chakera et al.   Clinical & Developmental Immunology

Increased Frequency of Circulating Follicular Helper T Cells in Patients with Rheumatoid Arthritis

(2012) Jie Ma et al.   Clinical & Developmental Immunology

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

(2012) Madelene Lindqvist et al.   JOURNAL OF CLINICAL INVESTIGATION

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

(2012) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The origins, function, and regulation of T follicular helper cells

(2012) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin 21 Correlates with T Cell and B Cell Subset Alterations in Systemic Lupus Erythematosus

(2012) B. TERRIER et al.   JOURNAL OF RHEUMATOLOGY

Follicular center helper T-cell (TFH) marker positive mycosis fungoides/Sezary syndrome

(2012) Howard J Meyerson et al.   MODERN PATHOLOGY

Inhibition of Aberrant Circulating Tfh Cell Proportions by Corticosteroids in Patients with Systemic Lupus Erythematosus

(2012) Xuebing Feng et al.   PLoS One

A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis

(2012) Rui Liu et al.   ARTHRITIS RESEARCH & THERAPY

IL-21 and IL-21 Receptor Expression in Lymphocytes and Neurons in Multiple Sclerosis Brain

(2011) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY

CD4+ T Lymphocytes with follicular helper phenotype (TFH) in patients with SH2D1A deficiency (XLP)

(2011) Ana Coraglia et al.   CLINICAL IMMUNOLOGY

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

Bcl6 Protein Expression Shapes Pre-Germinal Center B Cell Dynamics and Follicular Helper T Cell Heterogeneity

(2011) Masahiro Kitano et al.   IMMUNITY

Increased Frequency of Follicular Helper T Cells in Patients with Autoimmune Thyroid Disease

(2011) Chenlu Zhu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Upregulation of IL-21 Receptor on B Cells and IL-21 Secretion Distinguishes Novel 2009 H1N1 Vaccine Responders from Nonresponders among HIV-Infected Persons on Combination Antiretroviral Therapy

(2011) S. Pallikkuth et al.   JOURNAL OF IMMUNOLOGY

CXCR5 Expressing Human Central Memory CD4 T Cells and Their Relevance for Humoral Immune Responses

(2011) N. Chevalier et al.   JOURNAL OF IMMUNOLOGY

Follicular helper T cells: implications in neoplastic hematopathology

(2011) Philippe Gaulard et al.   SEMINARS IN DIAGNOSTIC PATHOLOGY

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus

(2011) Sebastian Dolff et al.   ARTHRITIS RESEARCH & THERAPY

Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1

(2011) Iliyana Mikell et al.   PLoS Pathogens

Juvenile dermatomyositis: new insights and new treatment strategies

(2011) Neil Martin et al.   Therapeutic Advances in Musculoskeletal Disease

Regulation of T follicular helper cell formation and function by antigen presenting cells

(2010) Elissa K Deenick et al.   CURRENT OPINION IN IMMUNOLOGY

The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation

(2010) T. Marafioti et al.   HAEMATOLOGICA

Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling

(2010) Elissa K. Deenick et al.   IMMUNITY

B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

(2010) Danielle T. Avery et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ectopic and high CXCL13 chemokine expression in myasthenia gravis with thymic lymphoid hyperplasia

(2010) Yu-Ming Shiao et al.   JOURNAL OF NEUROIMMUNOLOGY

Increased Interleukin 21 (IL-21) and IL-23 Are Associated with Increased Disease Activity and with Radiographic Status in Patients with Early Rheumatoid Arthritis

(2010) T. K. RASMUSSEN et al.   JOURNAL OF RHEUMATOLOGY

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

(2009) Nicholas Simpson et al.   ARTHRITIS AND RHEUMATISM

Advances in the understanding and management of angioimmunoblastic T-cell lymphoma

(2009) Laurence de Leval et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hyper-IgE syndrome

(2009) Yoshiyuki Minegishi   CURRENT OPINION IN IMMUNOLOGY

Human Dendritic Cells Induce the Differentiation of Interleukin-21-Producing T Follicular Helper-like Cells through Interleukin-12

(2009) Nathalie Schmitt et al.   IMMUNITY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12

(2009) Cindy S Ma et al.   IMMUNOLOGY AND CELL BIOLOGY

Elevated Production of B Cell Chemokine CXCL13 is Correlated with Systemic Lupus Erythematosus Disease Activity

(2009) C. K. Wong et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Primary Cutaneous CD4+ Small/Medium-sized Pleomorphic T-cell Lymphoma Expresses Follicular T-cell Markers

(2008) Socorro Maria Rodríguez Pinilla et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE