Post-transcriptional regulatory networks in immunity

A Polypyrimidine Tract-Binding Protein-Dependent Pathway of mRNA Stability Initiates with CpG Activation of Primary B Cells

(2014) J. F. Porter et al.   JOURNAL OF IMMUNOLOGY

Tristetraprolin Regulates CXCL1 (KC) mRNA Stability

(2014) S. Datta et al.   JOURNAL OF IMMUNOLOGY

microRNA Regulation of Inflammatory Responses

(2012) Ryan M. O'Connell et al.   Annual Review of Immunology

Developmental Origin and Functional Specialization of Mast Cell Subsets

(2012) Michael F. Gurish et al.   IMMUNITY

Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase

(2012) Tracy L Keller et al.   Nature Chemical Biology

Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E

(2012) Barbara Herdy et al.   NATURE IMMUNOLOGY

Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase

(2012) J. Xu et al.   NUCLEIC ACIDS RESEARCH

RNA-binding protein AUF1 represses Dicer expression

(2012) Kotb Abdelmohsen et al.   NUCLEIC ACIDS RESEARCH

AU-Rich Element-Mediated mRNA Decay Can Occur Independently of the miRNA Machinery in Mouse Embryonic Fibroblasts and Drosophila S2-Cells

(2012) Stephanie Helfer et al.   PLoS One

Eukaryotic Initiation Factor 2 Phosphorylation and Translational Control in Metabolism

(2012) Thomas D. Baird et al.   Advances in Nutrition

miR-27b Targets KSRP to Coordinate TLR4-Mediated Epithelial Defense against Cryptosporidium parvum Infection

(2012) Rui Zhou et al.   PLoS Pathogens

Tristetraprolin down-regulates IL-17 through mRNA destabilization

(2011) Hyun Hee Lee et al.   FEBS LETTERS

HuR function in disease

(2011) Subramanya Srikantan   Frontiers in Bioscience-Landmark

Stress puts TIA on TOP

(2011) P. Ivanov et al.   GENES & DEVELOPMENT

Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis

(2011) Anthie Yiakouvaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Cross Talk between Immunoglobulin Heavy-Chain Transcription and RNA Surveillance during B Cell Development

(2011) A. Tinguely et al.   MOLECULAR AND CELLULAR BIOLOGY

Chaperone Hsp27 Modulates AUF1 Proteolysis and AU-Rich Element-Mediated mRNA Degradation

(2011) A. M. Knapinska et al.   MOLECULAR AND CELLULAR BIOLOGY

Posttranscriptional Control of Type I Interferon Genes by KSRP in the Innate Immune Response against Viral Infection

(2011) W.-J. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

(2011) Neelanjan Mukherjee et al.   MOLECULAR CELL

Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR

(2011) Svetlana Lebedeva et al.   MOLECULAR CELL

Major source of antigenic peptides for the MHC class I pathway is produced during the pioneer round of mRNA translation

(2011) S. Apcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

External influences on the immune system via activation of the aryl hydrocarbon receptor

(2011) Brigitta Stockinger et al.   SEMINARS IN IMMUNOLOGY

AUF1 is involved in splenic follicular B cell maintenance

(2010) Navid Sadri et al.   BMC IMMUNOLOGY

The Pioneer Round of Translation: Features and Functions

(2010) Lynne E. Maquat et al.   CELL

The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs

(2010) Vicki Athanasopoulos et al.   FEBS Journal

KSRP, many functions for a single protein

(2010) Paola Briata   Frontiers in Bioscience-Landmark

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Multiple RNA Surveillance Mechanisms Cooperate to Reduce the Amount of Nonfunctional Ig  Transcripts

(2010) G. Chemin et al.   JOURNAL OF IMMUNOLOGY

Analysis of CUGBP1 Targets Identifies GU-Repeat Sequences That Mediate Rapid mRNA Decay

(2010) B. Rattenbacher et al.   MOLECULAR AND CELLULAR BIOLOGY

Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression

(2010) Elke Glasmacher et al.   NATURE IMMUNOLOGY

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

(2010) L. Furic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional insights into eukaryotic mRNA decapping

(2010) Sharon H. M. Ling et al.   Wiley Interdisciplinary Reviews-RNA

Nuclear quality control of RNA polymerase II transcripts

(2010) Manfred Schmid et al.   Wiley Interdisciplinary Reviews-RNA

Mechanisms of deadenylation-dependent decay

(2010) Chyi-Ying A. Chen et al.   Wiley Interdisciplinary Reviews-RNA

Networks controlling mRNA decay in the immune system

(2010) Johanna Schott et al.   Wiley Interdisciplinary Reviews-RNA

The role of AUF1 in regulated mRNA decay

(2010) Frances M. Gratacós et al.   Wiley Interdisciplinary Reviews-RNA

Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis

(2009) D. J. Stumpo et al.   BLOOD

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

(2009) Pamela Nicholson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Execution of nonsense-mediated mRNA decay: what defines a substrate?

(2009) Indrani Rebbapragada et al.   CURRENT OPINION IN CELL BIOLOGY

In vivo post-transcriptional regulation of CD154 in mouse CD4+ T cells

(2009) Stefano Vavassori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages

(2009) Tina Ruggiero et al.   FASEB JOURNAL

Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1β mRNA

(2009) Danuta Mizgalska et al.   FEBS Journal

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Dicer-Dependent MicroRNA Pathway Controls Invariant NKT Cell Development

(2009) M. Fedeli et al.   JOURNAL OF IMMUNOLOGY

Control of Thymic T Cell Maturation, Deletion and Egress by the RNA-Binding Protein HuR

(2009) O. Papadaki et al.   JOURNAL OF IMMUNOLOGY

The RNA-Binding Protein Elavl1/HuR Is Essential for Placental Branching Morphogenesis and Embryonic Development

(2009) V. Katsanou et al.   MOLECULAR AND CELLULAR BIOLOGY

Two-Site Phosphorylation of EPRS Coordinates Multimodal Regulation of Noncanonical Translational Control Activity

(2009) Abul Arif et al.   MOLECULAR CELL

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

(2009) Kazufumi Matsushita et al.   NATURE

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

(2009) Michele Trabucchi et al.   NATURE

Zcchc11-dependent uridylation of microRNA directs cytokine expression

(2009) Matthew R. Jones et al.   NATURE CELL BIOLOGY

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

(2009) Shengli Hao et al.   NATURE IMMUNOLOGY

Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response

(2009) M. S. Sundrud et al.   SCIENCE

The GAIT system: a gatekeeper of inflammatory gene expression

(2009) Rupak Mukhopadhyay et al.   TRENDS IN BIOCHEMICAL SCIENCES

Control of mRNA decay by phosphorylation of tristetraprolin

(2008) Heike Sandler et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage

(2008) Sergei B. Koralov et al.   CELL

Diverse molecular functions of Hu proteins

(2008) M. N. Hinman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

(2008) Pavel V Ivanov et al.   EMBO JOURNAL

Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'

(2008) T. E. Mullen et al.   GENES & DEVELOPMENT

Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape

(2008) Jessica B. Katz et al.   IMMUNOLOGICAL REVIEWS

Posttranscriptional regulation of IL-13 in T cells: Role of the RNA-binding protein HuR

(2008) Vincenzo Casolaro et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Separatecis-transPathways Post-transcriptionally Regulate Murine CD154 (CD40 Ligand) Expression

(2008) B. JoNell Hamilton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide Analysis Identifies Interleukin-10 mRNA as Target of Tristetraprolin

(2008) Georg Stoecklin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AUF1 Isoform-Specific Regulation of Anti-inflammatory IL10 Expression in Monocytes

(2008) Srijata Sarkar et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Auf1/Hnrnpd-Deficient Mice Develop Pruritic Inflammatory Skin Disease

(2008) Navid Sadri et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

7-Ketocholesterol Upregulates Interleukin-6 via Mechanisms That Are Distinct from Those of Tumor Necrosis Factor-α, in Vascular Smooth Muscle Cells

(2008) Si-Chan Sung et al.   JOURNAL OF VASCULAR RESEARCH

Genome-Wide Polysome Profiling Reveals an Inflammation-Responsive Posttranscriptional Operon in Gamma Interferon-Activated Monocytes

(2008) K. Vyas et al.   MOLECULAR AND CELLULAR BIOLOGY

Conserved GU-Rich Elements Mediate mRNA Decay by Binding to CUG-Binding Protein 1

(2008) Irina A. Vlasova et al.   MOLECULAR CELL

Translational control of the innate immune response through IRF-7

(2008) Rodney Colina et al.   NATURE

A stress-responsive RNA switch regulates VEGFA expression

(2008) Partho Sarothi Ray et al.   NATURE

Post-transcriptional control of cytokine production

(2008) Paul Anderson   NATURE IMMUNOLOGY

Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

(2008) Weiping Cao et al.   NATURE IMMUNOLOGY

Multifunctional deadenylase complexes diversify mRNA control

(2008) Aaron C. Goldstrohm et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

(2008) Andrea B Eberle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Competition between Stimulators and Antagonists of Upf Complex Recruitment Governs Human Nonsense-Mediated mRNA Decay

(2008) Guramrit Singh et al.   PLOS BIOLOGY

Posttranscriptional Gene Regulation by Spatial Rearrangement of the 3′ Untranslated Region

(2008) Andrea B Eberle et al.   PLOS BIOLOGY

MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components

(2007) Ananthi J. Asirvatham et al.   MOLECULAR IMMUNOLOGY