Networks controlling mRNA decay in the immune system

A Polypyrimidine Tract-Binding Protein-Dependent Pathway of mRNA Stability Initiates with CpG Activation of Primary B Cells

(2014) J. F. Porter et al.   JOURNAL OF IMMUNOLOGY

Tristetraprolin Regulates CXCL1 (KC) mRNA Stability

(2014) S. Datta et al.   JOURNAL OF IMMUNOLOGY

On track with P-bodies

(2010) Meeta Kulkarni et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

AUF1 is involved in splenic follicular B cell maintenance

(2010) Navid Sadri et al.   BMC IMMUNOLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis

(2009) D. J. Stumpo et al.   BLOOD

MicroRNA Control in the Immune System: Basic Principles

(2009) Changchun Xiao et al.   CELL

Stress granules

(2009) Paul Anderson et al.   CURRENT BIOLOGY

Onco-miR-155 targets SHIP1 to promote TNFα-dependent growth of B cell lymphomas

(2009) Irene M. Pedersen et al.   EMBO Molecular Medicine

In vivo post-transcriptional regulation of CD154 in mouse CD4+ T cells

(2009) Stefano Vavassori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Micro-RNA-155 inhibits IFN-γ signaling in CD4+ T cells

(2009) Arnob Banerjee et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inhibition of protein kinase Cδ reduces tristetraprolin expression by destabilizing its mRNA in activated macrophages

(2009) Tiina Leppänen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages

(2009) Tina Ruggiero et al.   FASEB JOURNAL

Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1β mRNA

(2009) Danuta Mizgalska et al.   FEBS Journal

The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophages

(2009) Corina Tudor et al.   FEBS LETTERS

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

(2009) Ariadne Androulidaki et al.   IMMUNITY

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

Formation of GW/P bodies as marker for microRNA-mediated regulation of innate immune signaling in THP-1 cells

(2009) Kaleb M Pauley et al.   IMMUNOLOGY AND CELL BIOLOGY

Interleukin-1 Receptor-associated Kinase 2 Is Critical for Lipopolysaccharide-mediated Post-transcriptional Control

(2009) Youzhong Wan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tristetraprolin Mediates Interferon-γ mRNA Decay

(2009) Rachel L. Ogilvie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-146a Is Critical for Endotoxin-induced Tolerance

(2009) Md A. Nahid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-155 Modulates the Pathogen Binding Ability of Dendritic Cells (DCs) by Down-regulation of DC-specific Intercellular Adhesion Molecule-3 Grabbing Non-integrin (DC-SIGN)

(2009) Rocio T. Martinez-Nunez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tristetraprolin Is Required for Full Anti-Inflammatory Response of Murine Macrophages to IL-10

(2009) B. Schaljo et al.   JOURNAL OF IMMUNOLOGY

Dicer-Dependent MicroRNA Pathway Controls Invariant NKT Cell Development

(2009) M. Fedeli et al.   JOURNAL OF IMMUNOLOGY

IL-17 Regulates CXCL1 mRNA Stability via an AUUUA/Tristetraprolin-Independent Sequence

(2009) S. Datta et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

(2009) J. Hou et al.   JOURNAL OF IMMUNOLOGY

Control of Thymic T Cell Maturation, Deletion and Egress by the RNA-Binding Protein HuR

(2009) O. Papadaki et al.   JOURNAL OF IMMUNOLOGY

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

(2009) Kazufumi Matsushita et al.   NATURE

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

(2009) Michele Trabucchi et al.   NATURE

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Zcchc11-dependent uridylation of microRNA directs cytokine expression

(2009) Matthew R. Jones et al.   NATURE CELL BIOLOGY

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

(2009) Shengli Hao et al.   NATURE IMMUNOLOGY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Inositol phosphatase SHIP1 is a primary target of miR-155

(2009) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

(2009) F. Bazzoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA

(2009) David G. Hendrickson et al.   PLOS BIOLOGY

Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage

(2008) Sergei B. Koralov et al.   CELL

MicroRNA-155 Is a Negative Regulator of Activation-Induced Cytidine Deaminase

(2008) Grace Teng et al.   IMMUNITY

MicroRNA-155 Suppresses Activation-Induced Cytidine Deaminase-Mediated Myc-Igh Translocation

(2008) Yair Dorsett et al.   IMMUNITY

Posttranscriptional regulation of IL-13 in T cells: Role of the RNA-binding protein HuR

(2008) Vincenzo Casolaro et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Similar Regulation of Human Inducible Nitric-oxide Synthase Expression by Different Isoforms of the RNA-binding Protein AUF1

(2008) Andrea Pautz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide Analysis Identifies Interleukin-10 mRNA as Target of Tristetraprolin

(2008) Georg Stoecklin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel CCCH-Zinc Finger Protein Family Regulates Proinflammatory Activation of Macrophages

(2008) Jian Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Auf1/Hnrnpd-Deficient Mice Develop Pruritic Inflammatory Skin Disease

(2008) Navid Sadri et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Epstein-Barr Virus-Induced miR-155 Attenuates NF- B Signaling and Stabilizes Latent Virus Persistence

(2008) F. Lu et al.   JOURNAL OF VIROLOGY

Posttranslational Modification of the AU-Rich Element Binding Protein HuR by Protein Kinase C  Elicits Angiotensin II-Induced Stabilization and Nuclear Export of Cyclooxygenase 2 mRNA

(2008) A. Doller et al.   MOLECULAR AND CELLULAR BIOLOGY

Conserved GU-Rich Elements Mediate mRNA Decay by Binding to CUG-Binding Protein 1

(2008) Irina A. Vlasova et al.   MOLECULAR CELL

Targeting mRNA Stability Arrests Inflammatory Bone Loss

(2008) Chetan S Patil et al.   MOLECULAR THERAPY

Endonucleolytic RNA cleavage by a eukaryotic exosome

(2008) Alice Lebreton et al.   NATURE

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Post-transcriptional control of cytokine production

(2008) Paul Anderson   NATURE IMMUNOLOGY

A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells

(2008) Angela Schwede et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Survey and Expression Profiling of CCCH-Zinc Finger Family Reveals a Functional Module in Macrophage Activation

(2008) Jian Liang et al.   PLoS One

The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2

(2008) S. Maitra et al.   RNA

Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins

(2007) Alexander Dalpke et al.   IMMUNOBIOLOGY

MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components

(2007) Ananthi J. Asirvatham et al.   MOLECULAR IMMUNOLOGY