Caspase-1 Activation via Rho GTPases: A Common Theme in Mucosal Infections?

The S. Typhimurium Effector SopE Induces Caspase-1 Activation in Stromal Cells to Initiate Gut Inflammation

(2009) Andreas J. Müller et al.   Cell Host & Microbe

Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System

(2009) Russell E. Vance et al.   Cell Host & Microbe

Lipocalin-2 Resistance Confers an Advantage to Salmonella enterica Serotype Typhimurium for Growth and Survival in the Inflamed Intestine

(2009) Manuela Raffatellu et al.   Cell Host & Microbe

The effector repertoire of enteropathogenic E. coli: ganging up on the host cell

(2009) Paul Dean et al.   CURRENT OPINION IN MICROBIOLOGY

Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1β release through pyrophosphates

(2009) Pablo Pelegrin et al.   EMBO JOURNAL

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics

(2009) Zhiwei Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The guanine-nucleotide-exchange factor BopE fromBurkholderia pseudomalleiadopts a compact version of theSalmonellaSopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42

(2008) Abhishek Upadhyay et al.   BIOCHEMICAL JOURNAL

Structure and Function of Salmonella SifA Indicate that Its Interactions with SKIP, SseJ, and RhoA Family GTPases Induce Endosomal Tubulation

(2008) Maikke B. Ohlson et al.   Cell Host & Microbe

Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens

(2008) Ana Arbeloa et al.   CELLULAR MICROBIOLOGY

EspT triggers formation of lamellipodia and membrane ruffles through activation of Rac-1 and Cdc42

(2008) Richard R. Bulgin et al.   CELLULAR MICROBIOLOGY

Nramp1 drives an accelerated inflammatory response duringSalmonella-induced colitis in mice

(2008) Yanet Valdez et al.   CELLULAR MICROBIOLOGY

NOD-like receptors (NLRs): bona fide intracellular microbial sensors

(2008) Michael H Shaw et al.   CURRENT OPINION IN IMMUNOLOGY

The microbial and danger signals that activate Nod-like receptors

(2008) Szilvia Benko et al.   CYTOKINE

Interleukin-1 Receptor Signaling Protects Mice from Lethal Intestinal Damage Caused by the Attaching and Effacing Pathogen Citrobacter rodentium

(2008) S. L. Lebeis et al.   INFECTION AND IMMUNITY

Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity

(2008) Juying Li et al.   JOURNAL OF CELL BIOLOGY

ThePseudomonas aeruginosa TypeIII secretion system plays a dual role in the regulation of caspase-1 mediated IL-1β maturation

(2008) M. Galle et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri

(2007) Abderrahman Hachani et al.   MICROBES AND INFECTION

Salmonellae interplay with host cells

(2007) Andrea Haraga et al.   NATURE REVIEWS MICROBIOLOGY