A killer choice for cancer immunotherapy

Chimeric Antigen Receptor Therapy for Cancer

(2013) David M. Barrett et al.   Annual Review of Medicine

Targeting of acute myeloid leukaemia by cytokine-induced killer cells redirected with a novel CD123-specific chimeric antigen receptor

(2013) Sarah Tettamanti et al.   BRITISH JOURNAL OF HAEMATOLOGY

CTLA-4 and PD-1/PD-L1 Blockade: New Immunotherapeutic Modalities with Durable Clinical Benefit in Melanoma Patients

(2013) P. A. Ott et al.   CLINICAL CANCER RESEARCH

Multivariate statistical data analysis as a tool to analyze ex vivo expansion dynamics of cytokine-induced killer cells

(2013) Cristina Zanon et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Enhancing cytokine-induced killer cell therapy of multiple myeloma

(2013) Chunsheng Liu et al.   EXPERIMENTAL HEMATOLOGY

Chimeric antigen receptors for the adoptive T cell therapy of hematologic malignancies

(2013) Marco L. Davila et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Cancer-Initiating Cells from Colorectal Cancer Patients Escape from T Cell-Mediated Immunosurveillance In Vitro through Membrane-Bound IL-4

(2013) A. Volonte et al.   JOURNAL OF IMMUNOLOGY

Upregulation of Adhesion Molecules on Leukemia Targets Improves the Efficacy of Cytotoxic T Cells Transduced With Chimeric Anti-CD19 Receptor

(2013) David Laurin et al.   JOURNAL OF IMMUNOTHERAPY

IL-15 Improves the Cytotoxicity of Cytokine-induced Killer Cells Against Leukemia Cells by Upregulating CD3+CD56+ Cells and Downregulating Regulatory T Cells As Well As IL-35

(2013) Qianshan Tao et al.   JOURNAL OF IMMUNOTHERAPY

Cytokine-induced killer cells promote antitumor immunity

(2013) Jingting Jiang et al.   Journal of Translational Medicine

Bevacizumab improves the antitumor efficacy of adoptive cytokine-induced killer cells therapy in non-small cell lung cancer models

(2013) Leilei Tao et al.   MEDICAL ONCOLOGY

Arming Cytokine-induced Killer Cells With Chimeric Antigen Receptors: CD28 Outperforms Combined CD28–OX40 “Super-stimulation”

(2013) Andreas A Hombach et al.   MOLECULAR THERAPY

Sunitinib Indirectly Enhanced Anti-Tumor Cytotoxicity of Cytokine-Induced Killer Cells and CD3+CD56+ Subset through the Co-Culturing Dendritic Cells

(2013) Adisak Wongkajornsilp et al.   PLoS One

CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

(2013) R. J. Brentjens et al.   Science Translational Medicine

Combination of E2F-1 promoter-regulated oncolytic adenovirus and cytokine-induced killer cells enhances the antitumor effects in an orthotopic rectal cancer model

(2013) Yang Yan et al.   TUMOR BIOLOGY

A role for CCL2 in both tumor progression and immunosurveillance

(2013) Ming Li et al.   OncoImmunology

Review of Chinese clinical trials on CIK cell treatment for malignancies

(2012) Xiao-Dong Li et al.   Clinical & Translational Oncology

Crosstalk Between Immune Cell and Oncolytic Vaccinia Therapy Enhances Tumor Trafficking and Antitumor Effects

(2012) Padma Sampath et al.   MOLECULAR THERAPY

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adoptive Immunotherapy with Cytokine-Induced Killer Cells for Patients with Relapsed Hematologic Malignancies after Allogeneic Hematopoietic Cell Transplantation

(2011) Ginna G. Laport et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

The cytotoxic potential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells

(2011) Eva Rettinger et al.   CYTOTHERAPY

Modulation of NKG2D-ligand Cell Surface Expression Enhances Immune Cell Therapy of Cancer

(2011) Baocheng Huang et al.   JOURNAL OF IMMUNOTHERAPY

T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

(2011) M. Kalos et al.   Science Translational Medicine

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

(2010) J. N. Kochenderfer et al.   BLOOD

Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor

(2010) B. Jena et al.   BLOOD

IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy

(2010) Mike W. Helms et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

In vivo imaging of immune cell trafficking in cancer

(2010) Luisa Ottobrini et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC)

(2010) C. Hontscha et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

(2010) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting Localized Immune Suppression Within the Tumor Through Repeat Cycles of Immune Cell-oncolytic Virus Combination Therapy

(2010) Stephen H Thorne et al.   MOLECULAR THERAPY

High-Dose Intensity Pulse Interleukin-2 with Famotidine in Metastatic Kidney Cancer

(2009) Walter D.Y. Quan et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Guided by the light: visualizing biomolecular processes in living animals with bioluminescence

(2009) Jennifer A Prescher et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

In vivo cytometry of antigen-specific t cells using19F MRI

(2009) Mangala Srinivas et al.   MAGNETIC RESONANCE IN MEDICINE

Experimental study on the treatment of intracerebral glioma xenograft with human cytokine-induced killer cells

(2008) Peng Wang et al.   CELLULAR IMMUNOLOGY

Inhibition of human cervical carcinoma growth by cytokine-induced killer cells in nude mouse xenograft model

(2008) Hwan Mook Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Monitoring the Efficacy of Adoptively Transferred Prostate Cancer-Targeted Human T Lymphocytes with PET and Bioluminescence Imaging

(2008) K. Dobrenkov et al.   JOURNAL OF NUCLEAR MEDICINE