Targeting of acute myeloid leukaemia by cytokine-induced killer cells redirected with a novel CD123-specific chimeric antigen receptor

Comparison of Different Suicide-Gene Strategies for the Safety Improvement of Genetically Manipulated T Cells

(2012) Virna Marin et al.   Human Gene Therapy Methods

Cytokine Induced Killer Cells as Promising Immunotherapy for Solid Tumors

(2012) Dario Sangiolo   Journal of Cancer

Suicide Gene Therapy to Increase the Safety of Chimeric Antigen Receptor-Redirected T Lymphocytes

(2012) Monica Casucci et al.   Journal of Cancer

Adoptive Immunotherapy with Cytokine-Induced Killer Cells for Patients with Relapsed Hematologic Malignancies after Allogeneic Hematopoietic Cell Transplantation

(2011) Ginna G. Laport et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

High levels of CD34+CD38low/-CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang (GOELAMS) study

(2011) F. Vergez et al.   HAEMATOLOGICA

Auger Electron Radioimmunotherapeutic Agent Specific for the CD123+/CD131- Phenotype of the Leukemia Stem Cell Population

(2011) J. V. Leyton et al.   JOURNAL OF NUCLEAR MEDICINE

Expression of complement components, receptors and regulators by human dendritic cells

(2011) Ke Li et al.   MOLECULAR IMMUNOLOGY

CARs on Track in the Clinic

(2011) Donald B Kohn et al.   MOLECULAR THERAPY

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

(2011) Antonio Di Stasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Progenitor cell dose determines the pace and completeness of engraftment in a xenograft model for cord blood transplantation

(2010) C. Liu et al.   BLOOD

Novel conjugates of single-chain Fv antibody fragments specific for stem cell antigen CD123 mediate potent death of acute myeloid leukaemia cells

(2010) Christoph Stein et al.   BRITISH JOURNAL OF HAEMATOLOGY

A recombinant trispecific single-chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting

(2010) Markus Kügler et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors

(2010) V. Marin et al.   HAEMATOLOGICA

Chimeric Antigen Receptor-Engineered T Cells for Immunotherapy of Cancer

(2010) Marc Cartellieri et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Cytokine-Induced NK-Like T Cells: From Bench to Bedside

(2010) Yeh Ching Linn et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Safer CARS

(2010) Helen E Heslop   MOLECULAR THERAPY

Treatment of Chronic Lymphocytic Leukemia With Genetically Targeted Autologous T Cells: Case Report of an Unforeseen Adverse Event in a Phase I Clinical Trial

(2010) Renier Brentjens et al.   MOLECULAR THERAPY

Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

(2010) Richard A Morgan et al.   MOLECULAR THERAPY

Monoclonal antibody therapy directed against human acute myeloid leukemia stem cells

(2010) R Majeti   ONCOGENE

Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor α Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells

(2009) Liqing Jin et al.   Cell Stem Cell

In vivo trafficking and survival of cytokine-induced killer cells resulting in minimal GVHD with retention of antitumor activity

(2008) R. Nishimura et al.   BLOOD

Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia

(2008) Arthur Frankel et al.   LEUKEMIA & LYMPHOMA