Rationale for treating primary Sjögren’s syndrome patients with an anti-CD6 monoclonal antibody (Itolizumab)

CD5 expression promotes multiple intracellular signaling pathways in B lymphocyte

(2012) Rizgar A. Mageed et al.   AUTOIMMUNITY REVIEWS

Diagnostic value of labial minor salivary gland biopsy for Sjögren's syndrome: A systematic review

(2012) Dewi Guellec et al.   AUTOIMMUNITY REVIEWS

Epigenetics and Sjogren’s Syndrome

(2012) Christelle Le Dantec et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The T cell in Sjogren's syndrome: Force majeure, not spectateur

(2012) Namrata Singh et al.   JOURNAL OF AUTOIMMUNITY

Low levels of vitamin-D are associated with neuropathy and lymphoma among patients with Sjögren’s syndrome

(2012) Nancy Agmon-Levin et al.   JOURNAL OF AUTOIMMUNITY

B cells in Sjögren's syndrome: From pathophysiology to diagnosis and treatment

(2012) Divi Cornec et al.   JOURNAL OF AUTOIMMUNITY

CD6 and Syntaxin Binding Protein 6 Variants and Response to Tumor Necrosis Factor Alpha Inhibitors in Danish Patients with Rheumatoid Arthritis

(2012) Sophine B. Krintel et al.   PLoS One

In Sjögren's syndrome, B lymphocytes induce epithelial cells of salivary glands into apoptosis through protein kinase C delta activation

(2011) Marie-Michèle Varin et al.   AUTOIMMUNITY REVIEWS

HLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies

(2011) Paola Cruz-Tapias et al.   AUTOIMMUNITY REVIEWS

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation

(2011) Marta I. Oliveira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The CD6 Multiple Sclerosis Susceptibility Allele Is Associated with Alterations in CD4+ T Cell Proliferation

(2011) D. M. Kofler et al.   JOURNAL OF IMMUNOLOGY

6thAnnual European Antibody Congress 2010

(2011) Alain Beck et al.   mAbs

Antibody-based therapeutics to watch in 2011

(2011) Janice M. Reichert   mAbs

Significance of B cells and B cell clonality in Sjögren's syndrome

(2010) Pierre Youinou et al.   ARTHRITIS AND RHEUMATISM

Aberrant expression of CD6 on B-cell subsets from patients with Sjögren’s syndrome

(2010) Ruby Alonso et al.   JOURNAL OF AUTOIMMUNITY

Memory B-cell aggregates in skin biopsy are diagnostic for primary Sjögren’s syndrome

(2010) Anne-Marie Roguedas et al.   JOURNAL OF AUTOIMMUNITY

Epigenetics and autoimmunity

(2010) Wesley H. Brooks et al.   JOURNAL OF AUTOIMMUNITY

The CD6 Scavenger Receptor Is Differentially Expressed on a CD56dim Natural Killer Cell Subpopulation and Contributes to Natural Killer-Derived Cytokine and Chemokine Secretion

(2010) Monika Braun et al.   Journal of Innate Immunity

Characteristics of the minor salivary gland infiltrates in Sjögren's syndrome

(2009) Maria I. Christodoulou et al.   JOURNAL OF AUTOIMMUNITY

Ectopic Germinal Centers Are Rare in Sjogren's Syndrome Salivary Glands and Do Not Exclude Autoreactive B Cells

(2009) L. Le Pottier et al.   JOURNAL OF IMMUNOLOGY

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

(2009) Philip L De Jager et al.   NATURE GENETICS

Towards the Definition of a Chimpanzee and Human Conserved CD6 Domain 1 Epitope Recognized by T1 Monoclonal Antibody

(2008) Ruby Alonso et al.   HYBRIDOMA

Long-term outcomes of nonconditioned patients with severe combined immunodeficiency transplanted with HLA-identical or haploidentical bone marrow depleted of T cells with anti-CD6 mAb

(2008) Niraj C. Patel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY