Immune modulation of inflammatory conditions: regulatory T cells for treatment of GvHD

Efficient and Selective Prevention of GVHD by Antigen-Specific Induced Tregs via Linked-Suppression in Mice

(2011) Kenrick Semple et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells

(2011) T. Solstad et al.   BLOOD

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Regulatory T cells in stem cell transplantation: strategies and first clinical experiences

(2011) Matthias Edinger et al.   CURRENT OPINION IN IMMUNOLOGY

Mouse models of graft-versus-host disease: advances and limitations

(2011) M. A. Schroeder et al.   Disease Models & Mechanisms

Separation of human CD4+CD39+ T cells by magnetic beads reveals two phenotypically and functionally different subsets

(2011) Patrick J. Schuler et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

(2011) John Koreth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity

(2011) K. L. Hippen et al.   Science Translational Medicine

Natural killer cell engineering for cellular therapy of cancer

(2011) D. R. Shook et al.   TISSUE ANTIGENS

NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects

(2010) J. A. Olson et al.   BLOOD

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Allogeneic natural killer cells for refractory lymphoma

(2010) Veronika Bachanova et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Sirolimus immunosuppression for graft-versus-host disease prophylaxis and therapy: an update

(2010) Corey Cutler et al.   CURRENT OPINION IN HEMATOLOGY

A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer

(2010) Melissa A. Geller et al.   CYTOTHERAPY

Isolation and expansion of human natural T regulatory cells for cellular therapy

(2010) Rajendra Pahwa et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The immunosuppressive pipeline: Meeting unmet needs in liver transplantation

(2010) Nazia Selzner et al.   LIVER TRANSPLANTATION

Regulatory T cells in transplantation: does extracellular adenosine triphosphate metabolism through CD39 play a crucial role?

(2010) Francisco Salcido-Ochoa et al.   Transplantation Reviews

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

(2009) James L. Riley et al.   IMMUNITY

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression

(2009) Magis Mandapathil et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Genzyme backs Osiris, despite Prochymal flop

(2009) Malorye Allison   NATURE BIOTECHNOLOGY

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

(2009) Noriko Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirolimus, Tacrolimus, and Low-Dose Methotrexate as Graft-versus-Host Disease Prophylaxis in Related and Unrelated Donor Reduced-Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation

(2008) Edwin P. Alyea et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Rabbit ATG but not horse ATG promotes expansion of functional CD4+CD25highFOXP3+ regulatory T cells in vitro

(2008) X. Feng et al.   BLOOD

CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells

(2008) M. Kleinewietfeld et al.   BLOOD

Calcineurin inhibitor-free GVHD prophylaxis with sirolimus, mycophenolate mofetil and ATG in Allo-SCT for leukemia patients with high relapse risk: an observational cohort study

(2008) M Schleuning et al.   BONE MARROW TRANSPLANTATION

Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes

(2008) A. L. Putnam et al.   DIABETES

High purity and yield of natural Tregs from cord blood using a single step selection method

(2008) Daniel Figueroa-Tentori et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

(2008) Qizhi Tang et al.   NATURE IMMUNOLOGY