Natural killer cell engineering for cellular therapy of cancer

Adoptive Transfer of Gene-Modified Primary NK Cells Can Specifically Inhibit Tumor Progression In Vivo

(2014) H. J. Pegram et al.   JOURNAL OF IMMUNOLOGY

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

(2011) M. Kalos et al.   Science Translational Medicine

Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation

(2010) L. Moretta et al.   BLOOD

Novel Gamma-Chain Cytokines as Candidate Immune Modulators in Immune Therapies for Cancer

(2010) Natasha M. Fewkes et al.   CANCER JOURNAL

Cytotoxicity of Activated Natural Killer Cells against Pediatric Solid Tumors

(2010) D. Cho et al.   CLINICAL CANCER RESEARCH

NKAML: A Pilot Study to Determine the Safety and Feasibility of Haploidentical Natural Killer Cell Transplantation in Childhood Acute Myeloid Leukemia

(2010) Jeffrey E. Rubnitz et al.   JOURNAL OF CLINICAL ONCOLOGY

Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells

(2010) C. Krieg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting human natural killer cell subset function revealed cytolytic CD56dimCD16+ NK cells as rapid producers of abundant IFN-  on activation

(2010) A. De Maria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells

(2009) F. Romagne et al.   BLOOD

Replicative potential of human natural killer cells

(2009) Hiroyuki Fujisaki et al.   BRITISH JOURNAL OF HAEMATOLOGY

Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method

(2009) L Li et al.   CANCER GENE THERAPY

Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy

(2009) H. Fujisaki et al.   CANCER RESEARCH

KIR and HLA Genotypes Are Associated with Disease Progression and Survival following Autologous Hematopoietic Stem Cell Transplantation for High-Risk Neuroblastoma

(2009) J. M. Venstrom et al.   CLINICAL CANCER RESEARCH

2B4 (CD244) Signaling by Recombinant Antigen-specific Chimeric Receptors Costimulates Natural Killer Cell Activation to Leukemia and Neuroblastoma Cells

(2009) B. Altvater et al.   CLINICAL CANCER RESEARCH

Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells

(2009) Maria Berg et al.   CYTOTHERAPY

Up-regulation of NK Cell Activating Receptors Following Allogeneic Hematopoietic Stem Cell Transplantation under a Lymphodepleting Reduced Intensity Regimen is Associated with Elevated IL-15 Levels

(2008) Michael Boyiadzis et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components

(2008) E. Alici et al.   BLOOD

Human natural killer cells

(2008) M. A. Caligiuri   BLOOD

Natural killer cell immunotherapy for cancer: a new hope

(2008) S. Srivastava et al.   CYTOTHERAPY

Natural Killer Cells in Innate Immunity and Cancer

(2008) Brian Becknell et al.   JOURNAL OF IMMUNOTHERAPY

Permanent silencing of NKG2A expression for cell-based therapeutics

(2008) Constança Figueiredo et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas

(2008) A. Kruschinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA