The Ups and Downs of Modelling Mood Disorders in Rodents

Epigenetic programming of the HPA axis: Early life decides

(2016) Chris Murgatroyd et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Glutamate Receptor Antagonists as Fast-Acting Therapeutic Alternatives for the Treatment of Depression: Ketamine and Other Compounds

(2014) Mark J. Niciu et al.   Annual Review of Pharmacology and Toxicology

Postpartum Depression: Current Status and Future Directions

(2013) Michael W. O'Hara et al.   Annual Review of Clinical Psychology

Human Biomarkers of Rapid Antidepressant Effects

(2013) Carlos A. Zarate et al.   BIOLOGICAL PSYCHIATRY

Towards translational rodent models of depression

(2013) Olivia F. O’Leary et al.   CELL AND TISSUE RESEARCH

microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus

(2013) Richard M. O'Connor et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A review of ketamine in affective disorders: Current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action

(2013) Marie Naughton et al.   JOURNAL OF AFFECTIVE DISORDERS

Innovative Drugs to Treat Depression: Did Animal Models Fail to Be Predictive or Did Clinical Trials Fail to Detect Effects?

(2013) Catherine Belzung   NEUROPSYCHOPHARMACOLOGY

A Translational Rodent Assay of Affective Biases in Depression and Antidepressant Therapy

(2013) Sarah A Stuart et al.   NEUROPSYCHOPHARMACOLOGY

Differential effects of baclofen and oxytocin on the increased ethanol consumption following chronic psychosocial stress in mice

(2012) Sebastian Peters et al.   ADDICTION BIOLOGY

A Randomized Trial of a Low-Trapping Nonselective N-Methyl-D-Aspartate Channel Blocker in Major Depression

(2012) Carlos A. Zarate et al.   BIOLOGICAL PSYCHIATRY

A glass full of optimism: Enrichment effects on cognitive bias in a rat model of depression

(2012) Sophie Helene Richter et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Time matters: pathological effects of repeated psychosocial stress during the active, but not inactive, phase of male mice

(2012) Manuela S Bartlang et al.   JOURNAL OF ENDOCRINOLOGY

Vesicular signalling and immune modulation as hedonic fingerprints: proteomic profiling in the chronic mild stress depression model

(2012) Christina F Bisgaard et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Prediction of susceptibility to major depression by a model of interactions of multiple functional genetic variants and environmental factors

(2012) M-L Wong et al.   MOLECULAR PSYCHIATRY

Using the rat forced swim test to assess antidepressant-like activity in rodents

(2012) David A Slattery et al.   Nature Protocols

A New Mouse Model for Mania Shares Genetic Correlates with Human Bipolar Disorder

(2012) Michael C. Saul et al.   PLoS One

Are We Getting Closer to Valid Translational Models for Major Depression?

(2012) O. Berton et al.   SCIENCE

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Predictive animal models of mania: hits, misses and future directions

(2011) Jared W Young et al.   BRITISH JOURNAL OF PHARMACOLOGY

Discovering imaging endophenotypes for major depression

(2011) G Hasler et al.   MOLECULAR PSYCHIATRY

Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression

(2011) R M O'Connor et al.   MOLECULAR PSYCHIATRY

Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice

(2011) E Beurel et al.   MOLECULAR PSYCHIATRY

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

Neural mechanisms of the cognitive model of depression

(2011) Seth G. Disner et al.   NATURE REVIEWS NEUROSCIENCE

Emerging roles of epigenetic mechanisms in the enduring effects of early-life stress and experience on learning and memory

(2011) Shawn McClelland et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

From Stress to Postpartum Mood and Anxiety Disorders: How Chronic Peripartum Stress Can Impair Maternal Adaptations

(2011) Katharina M. Hillerer et al.   NEUROENDOCRINOLOGY

Establishing a learned-helplessness effect paradigm in C57BL/6 mice: Behavioural evidence for emotional, motivational and cognitive effects of aversive uncontrollability per se

(2011) Christopher R. Pryce et al.   NEUROPHARMACOLOGY

Pharmacological Blockade of 5-HT7 Receptors as a Putative Fast Acting Antidepressant Strategy

(2011) Ouissame Mnie-Filali et al.   NEUROPSYCHOPHARMACOLOGY

High-fat diet selectively protects against the effects of chronic social stress in the mouse

(2011) B.C. Finger et al.   NEUROSCIENCE

Biomarkers of anhedonic-like behavior, antidepressant drug refraction, and stress resilience in a rat model of depression

(2011) T. Christensen et al.   NEUROSCIENCE

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression

(2011) Brian Leonard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Helplessness: A systematic translational review of theory and evidence for its relevance to understanding and treating depression

(2011) Christopher R. Pryce et al.   PHARMACOLOGY & THERAPEUTICS

Stress and animal models of inflammatory bowel disease—An update on the role of the hypothalamo–pituitary–adrenal axis

(2011) S.O. Reber   PSYCHONEUROENDOCRINOLOGY

Behavioural consequences of two chronic psychosocial stress paradigms: Anxiety without depression

(2011) David A. Slattery et al.   PSYCHONEUROENDOCRINOLOGY

Rodent models in depression research: Classical strategies and new directions

(2010) Daniela D. Pollak et al.   ANNALS OF MEDICINE

The suitability of 129SvEv mice for studying depressive-like behaviour: Both males and females develop learned helplessness

(2010) Sabine Chourbaji et al.   BEHAVIOURAL BRAIN RESEARCH

Reward and Punishment Processing in Depression

(2010) Neir Eshel et al.   BIOLOGICAL PSYCHIATRY

Open questions in current models of antidepressant action

(2010) A Tanti et al.   BRITISH JOURNAL OF PHARMACOLOGY

The modification of attentional bias to emotional information: A review of the techniques, mechanisms, and relevance to emotional disorders

(2010) M. Browning et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Sex differences in pharmacokinetics of antidepressants

(2010) Nikolaos Kokras et al.   Expert Opinion on Drug Metabolism & Toxicology

Transient inactivation of the infralimbic cortex induces antidepressant-like effects in the rat

(2010) David A Slattery et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Translational research in bipolar disorder: emerging insights from genetically based models

(2010) G Chen et al.   MOLECULAR PSYCHIATRY

Days out of role due to common physical and mental conditions: results from the WHO World Mental Health surveys

(2010) J Alonso et al.   MOLECULAR PSYCHIATRY

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Neonatal maternal separation exacerbates the reward-enhancing effect of acute amphetamine administration and the anhedonic effect of repeated social defeat in adult rats

(2010) A. Der-Avakian et al.   NEUROSCIENCE

Cross-species assessments of motor and exploratory behavior related to bipolar disorder

(2010) Brook L. Henry et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Animal models of depression and anxiety: What do they tell us about human condition?

(2010) I.D. Neumann et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A translational research framework for enhanced validity of mouse models of psychopathological states in depression

(2010) Christopher R. Pryce et al.   PSYCHONEUROENDOCRINOLOGY

A Glutamate Pathway to Faster-Acting Antidepressants?

(2010) J. F. Cryan et al.   SCIENCE

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Sex Differences in Animal Models of Depression and Antidepressant Response

(2009) Christina Dalla et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

The Female Urine Sniffing Test: A Novel Approach for Assessing Reward-Seeking Behavior in Rodents

(2009) Oz Malkesman et al.   BIOLOGICAL PSYCHIATRY

Antidepressant-Like Effects of Medial Prefrontal Cortex Deep Brain Stimulation in Rats

(2009) Clement Hamani et al.   BIOLOGICAL PSYCHIATRY

Reverse translational strategies for developing animal models of bipolar disorder

(2009) O. Malkesman et al.   Disease Models & Mechanisms

Ageing abolishes the effects of fluoxetine on neurogenesis

(2009) S Couillard-Despres et al.   MOLECULAR PSYCHIATRY

Ambiguous-Cue Interpretation is Biased Under Stress- and Depression-Like States in Rats

(2009) Thomas Enkel et al.   NEUROPSYCHOPHARMACOLOGY

A Hypomorphic Vasopressin Allele Prevents Anxiety-Related Behavior

(2009) Mirjam Bunck et al.   PLoS One

Depression during pregnancy and postpartum: Contribution of stress and ovarian hormones

(2009) S. Brummelte et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Simultaneous anhedonia and exaggerated locomotor activation in an animal model of depression

(2009) Thomas Romeas et al.   PSYCHOPHARMACOLOGY

Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes

(2008) E Keen-Rhinehart et al.   MOLECULAR PSYCHIATRY

An Animal Model of a Behavioral Intervention for Depression

(2008) Daniela D. Pollak et al.   NEURON

Glutamate receptors as targets of protein kinase C in the pathophysiology and treatment of animal models of Mania

(2008) Steven T. Szabo et al.   NEUROPHARMACOLOGY

Removing Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models

(2008) Athina Markou et al.   NEUROPSYCHOPHARMACOLOGY

The inflammatory response to social defeat is increased in older mice

(2007) Steven G. Kinsey et al.   PHYSIOLOGY & BEHAVIOR