Journal
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
Volume 15, Issue 6, Pages 1415-1424Publisher
IEEE COMPUTER SOC
DOI: 10.1109/TVCG.2009.177
Keywords
Particle Systems; Crease Features; Ridge and Valley Detection; Lung CT; Diffusion Tensor MRI
Categories
Funding
- NCRR NIH HHS [U41 RR019703-01A2, P41 RR013218, P41 RR013218-12S1, U41 RR019703, P41-RR13218] Funding Source: Medline
- NHLBI NIH HHS [5U01 HL089856-02, U01 HL089856-02, U01 HL089856] Funding Source: Medline
- NIMH NIH HHS [R01-MH074794, R01 MH074794, R01 MH074794-01A2] Funding Source: Medline
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Particle systems have gained importance as a methodology for sampling implicit surfaces and segmented objects to improve mesh generation and shape analysis. We propose that particle systems have a significantly more general role in sampling structure from unsegmented data. We describe a particle system that computes samplings of crease features (i.e. ridges and valleys, as lines or surfaces) that effectively represent many anatomical structures in scanned medical data. Because structure naturally exists at a range of sizes relative to the image resolution, computer vision has developed the theory of scale-space, which considers an n-D image as an (n + 1)-D stack of images at different blurring levels. Our scale-space particles move through continuous four-dimensional scale-space according to spatial constraints imposed by the crease features, a particle-image energy that draws particles towards scales of maximal feature strength, and an inter-particle energy that controls sampling density in space and scale. To make scale-space practical for large three-dimensional data, we present a spline-based interpolation across scale from a small number of pre-computed blurrings at optimally selected scales. The configuration of the particle system is visualized with tensor glyphs that display information about the local Hessian of the image, and the scale of the particle. We use scale-space particles to sample the complex three-dimensional branching structure of airways in lung CT, and the major white matter structures in brain DTI.
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