Journal
MATERIALS LETTERS
Volume 141, Issue -, Pages 55-58Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2014.10.144
Keywords
Natural polymer; Polyhydroxyalkanoate; Low crystalline; Elastic properties; Thin films; Biomaterial
Funding
- HIR-MoE Grant [UM.C/625/1/HIR/ MOHE/MED/04, E000003-20001]
- [FP025/2010B]
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In the present study, we developed an unmodified/raw Medium chain length -PHA (MCL-PHA) polyhydroxyalkanoate (PHA), natural microbial polyester by using cost-effective saponified palm kernel oil (SPKO) technique. The functional groups, elemental composition, phase purity, water contact angle, and in vitro human-derived mesenchymal stromal cell attachment were examined. FTIR confirmed the presence of functional groups corresponding to alkyl halide, alkyne, hydroxyl group, and alkane groups, while XRD and EDX results revealed its phase purity and presence of elements such as carbon and oxygen respectively. SEM and confocal microscope analyses revealed that the bin-material supports cell attachment and this was further confirmed through cell viability assay. In conclusion, the characterization and compatibility studies revealed that this novel scaffold could be a potential candidate for possible tissue engineering applications. (C) 2014 Published by Elsevier B.V.
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