6-Bromohypaphorine from Marine Nudibranch Mollusk Hermissenda crassicornis is an Agonist of Human α7 Nicotinic Acetylcholine Receptor

Marine Natural Products Acting on the Acetylcholine-Binding Protein and Nicotinic Receptors: From Computer Modeling to Binding Studies and Electrophysiology

(2014) Denis Kudryavtsev et al.   Marine Drugs

Conotoxin Gene Superfamilies

(2014) Samuel Robinson et al.   Marine Drugs

Water-soluble LYNX1 Residues Important for Interaction with Muscle-type and/or Neuronal Nicotinic Receptors

(2013) Ekaterina N. Lyukmanova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA

(2012) Layla Azam et al.   JOURNAL OF NEUROCHEMISTRY

Synthesis and Bioactivity of Secondary Metabolites from Marine Sponges Containing Dibrominated Indolic Systems

(2012) Adriano Mollica et al.   MOLECULES

Assembly of nicotinic and other Cys-loop receptors

(2011) Victor Tsetlin et al.   JOURNAL OF NEUROCHEMISTRY

Bioactive Indole Derivatives from the South Pacific Marine Sponges Rhopaloeides odorabile and Hyrtios sp.

(2011) Arlette Longeon et al.   Marine Drugs

Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization

(2011) Toby Collins et al.   NEUROPHARMACOLOGY

Naturally Occurring and Synthetic Peptides Acting on Nicotinic Acetylcholine Receptors

(2009) Igor Kasheverov et al.   CURRENT PHARMACEUTICAL DESIGN

An Allosteric Modulator of  7 Nicotinic Receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), Causes Conformational Changes in the Extracellular Ligand Binding Domain Similar to Those Caused by Acetylcholine

(2009) S. C. Barron et al.   MOLECULAR PHARMACOLOGY

Hypaphorine, an indole alkaloid from Erythrina velutina, induced sleep on normal mice

(2008) Masaaki Ozawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Drug development from marine natural products

(2008) Tadeusz F. Molinski et al.   NATURE REVIEWS DRUG DISCOVERY

Potentiation of  7 nicotinic acetylcholine receptors via an allosteric transmembrane site

(2008) G. T. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA