Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA

Structure-Activity Studies on Alpha-Conotoxins

(2012) Markus Muttenthaler et al.   CURRENT PHARMACEUTICAL DESIGN

New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer

(2012) Anna Chikova et al.   LIFE SCIENCES

Naturally-expressed nicotinic acetylcholine receptor subtypes

(2011) Jie Wu et al.   BIOCHEMICAL PHARMACOLOGY

Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain

(2011) Guangrong Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (CaV2.2) calcium channels

(2011) David J Adams et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nicotinic Acetylcholine Receptor-Based Blockade: Applications of Molecular Targets for Cancer Therapy

(2011) C.-H. Wu et al.   CLINICAL CANCER RESEARCH

The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic

(2011) Joseph R. Holtman et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The efferent medial olivocochlear-hair cell synapse

(2011) Ana Belén Elgoyhen et al.   JOURNAL OF PHYSIOLOGY-PARIS

Naturally Occurring Variants of Human Α9 Nicotinic Receptor Differentially Affect Bronchial Cell Proliferation and Transformation

(2011) Anna Chikova et al.   PLoS One

Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells

(2010) Chia-Hwa Lee et al.   BREAST CANCER RESEARCH AND TREATMENT

Subtype-selective conopeptides targeted to nicotinic receptors:Concerted discovery and biomedical applications

(2010) Baldomero M Olivera et al.   Channels

Overexpression and Activation of the α9-Nicotinic Receptor During Tumorigenesis in Human Breast Epithelial Cells

(2010) Chia-Hwa Lee et al.   JNCI-Journal of the National Cancer Institute

Tea polyphenol (−)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells

(2010) Shih-Hsin Tu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain

(2010) Harry Klimis et al.   PAIN

Synthetic α-Conotoxin Mutants as Probes for Studying Nicotinic Acetylcholine Receptors and in the Development of Novel Drug Leads

(2010) Christopher J. Armishaw   Toxins

Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors

(2009) Layla Azam et al.   ACTA PHARMACOLOGICA SINICA

Alpha9 nicotinic acetylcholine receptors and the treatment of pain

(2009) J. Michael McIntosh et al.   BIOCHEMICAL PHARMACOLOGY

Naturally Occurring and Synthetic Peptides Acting on Nicotinic Acetylcholine Receptors

(2009) Igor Kasheverov et al.   CURRENT PHARMACEUTICAL DESIGN

Scanning Mutagenesis of α-Conotoxin Vc1.1 Reveals Residues Crucial for Activity at the α9α10 Nicotinic Acetylcholine Receptor

(2009) Reena Halai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function

(2009) Edson X. Albuquerque et al.   PHYSIOLOGICAL REVIEWS

Molecular modeling of the α9α10 nicotinic acetylcholine receptor subtype

(2008) Edwin G. Pérez et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Conus Venoms - A Rich Source of Peptide-Based Therapeutics

(2008) Tiffany Han et al.   CURRENT PHARMACEUTICAL DESIGN

The three-dimensional structure of the analgesic α-conotoxin, RgIA

(2008) Richard J. Clark et al.   FEBS LETTERS

α-RgIA, a Novel Conotoxin That Blocks the α9α10 nAChR: Structure and Identification of Key Receptor-Binding Residues

(2008) Michael Ellison et al.   JOURNAL OF MOLECULAR BIOLOGY

Diversity of vertebrate nicotinic acetylcholine receptors

(2008) Neil S. Millar et al.   NEUROPHARMACOLOGY