Mtss1 is a critical epigenetically regulated tumor suppressor in CML

Missing-in-Metastasis regulates cell motility and invasion via PTPδ-mediated changes in SRC activity

(2015) Fauzia Chaudhary et al.   BIOCHEMICAL JOURNAL

Downregulation of MTSS1 expression is an independent prognosticator in squamous cell carcinoma of the lung

(2015) G Kayser et al.   BRITISH JOURNAL OF CANCER

EGF induces microRNAs that target suppressors of cell migration: miR-15b targetsMTSS1in breast cancer

(2015) Merav Kedmi et al.   Science Signaling

EGF induces microRNAs that target suppressors of cell migration: miR-15b targetsMTSS1in breast cancer

(2015) Merav Kedmi et al.   Science Signaling

Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia

(2015) Mirle Schemionek et al.   PLoS One

SCFβ-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration

(2015) Jiateng Zhong et al.   Oncotarget

Whole genome expression profiling of blood cells in ovarian cancer patients -Prognostic impact of the CYP1B1, MTSS1, NCALD, and NOP14 genes

(2015) Helena S. Isaksson et al.   Oncotarget

Selectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche

(2014) D. S. Krause et al.   BLOOD

The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells

(2014) K. Rothe et al.   BLOOD

MTSS1 is a metastasis driver in a subset of human melanomas

(2014) Kirsten D. Mertz et al.   Nature Communications

Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

(2013) E. Bolton-Gillespie et al.   BLOOD

Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt- -catenin signaling

(2013) B. Zhang et al.   BLOOD

PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells

(2013) Paolo Neviani et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-135b regulates metastasis suppressor 1 expression and promotes migration and invasion in colorectal cancer

(2013) Weiyun Wu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Suppression of MIM by microRNA-182 activates RhoA and promotes breast cancer metastasis

(2013) R Lei et al.   ONCOGENE

Dimerization is necessary for MIM-mediated membrane deformation and endocytosis

(2012) Meng Cao et al.   BIOCHEMICAL JOURNAL

MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma

(2012) Jian Wang et al.   BMC CANCER

Knock-down of Kaiso induces proliferation and blocks granulocytic differentiation in blast crisis of chronic myeloid leukemia

(2012) Jaime Cofre et al.   Cancer Cell International

The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells

(2012) Haojian Zhang et al.   NATURE GENETICS

Novel imatinib-sensitive PDGFRA-activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease

(2011) C. Elling et al.   BLOOD

CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia

(2011) H. Makishima et al.   BLOOD

Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival

(2011) A. Hamilton et al.   BLOOD

Low BCR-ABL expression levels in hematopoietic precursor cells enable persistence of chronic myeloid leukemia under imatinib

(2011) A. Kumari et al.   BLOOD

Procoagulant activity induced by vascular injury determines contribution of elevated factor VIII to thrombosis and thrombus stability in mice

(2011) K. R. Machlus et al.   BLOOD

Rho Kinase Regulates the Survival and Transformation of Cells Bearing Oncogenic Forms of KIT, FLT3, and BCR-ABL

(2011) Raghuveer Singh Mali et al.   CANCER CELL

IRF8 Regulates Acid Ceramidase Expression to Mediate Apoptosis and Suppresses Myelogeneous Leukemia

(2011) X. Hu et al.   CANCER RESEARCH

BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia

(2011) Christian Hurtz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance

(2011) Fei Xie et al.   Journal of Translational Medicine

Role of stromal microenvironment in nonpharmacological resistance of CML to imatinib through Lyn/CXCR4 interactions in lipid rafts

(2011) Y Tabe et al.   LEUKEMIA

Leukemic spleen cells are more potent than bone marrow-derived cells in a transgenic mouse model of CML

(2011) M Schemionek et al.   LEUKEMIA

Mice deficient in MIM expression are predisposed to lymphomagenesis

(2011) D Yu et al.   ONCOGENE

MTSS1, a novel target of DNA methyltransferase 3B, functions as a tumor suppressor in hepatocellular carcinoma

(2011) H Fan et al.   ONCOGENE

BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells

(2010) M. Schemionek et al.   BLOOD

Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor

(2010) Y. Benita et al.   BLOOD

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

(2010) Amie S. Corbin et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group

(2010) Torsten Haferlach et al.   JOURNAL OF CLINICAL ONCOLOGY

Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells

(2010) D. Kuck et al.   MOLECULAR CANCER THERAPEUTICS

A Comparison of Azacitidine and Decitabine Activities in Acute Myeloid Leukemia Cell Lines

(2010) Paul W. Hollenbach et al.   PLoS One

MOODS: fast search for position weight matrix matches in DNA sequences

(2009) J. Korhonen et al.   BIOINFORMATICS

Finding evolutionarily conserved cis-regulatory modules with a universal set of motifs

(2009) Bartek Wilczynski et al.   BMC BIOINFORMATICS

An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study prephase

(2008) Alexander Kohlmann et al.   BRITISH JOURNAL OF HAEMATOLOGY

Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis

(2008) E K Thomas et al.   LEUKEMIA

Anomalous dynamics of cell migration

(2008) P. Dieterich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA