HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α
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Title
HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α
Authors
Keywords
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Journal
LEUKEMIA
Volume 29, Issue 6, Pages 1366-1378
Publisher
Springer Nature
Online
2015-01-12
DOI
10.1038/leu.2015.8
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Related references
Note: Only part of the references are listed.- Pharmacologic increase in HIF1 enhances hematopoietic stem and progenitor homing and engraftment
- (2013) J. M. Speth et al. BLOOD
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- (2013) F. Torossian et al. BLOOD
- CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
- (2013) Adam Greenbaum et al. NATURE
- Targeting the Hypoxia-Sensing Pathway in Clinical Hematology
- (2013) Catherine E. Forristal et al. Stem Cells Translational Medicine
- Retrospective comparison of filgrastim plus plerixafor to other regimens for remobilization after primary mobilization failure: Clinical and economic outcomes
- (2012) Janelle B. Perkins et al. AMERICAN JOURNAL OF HEMATOLOGY
- HIF-1 deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency
- (2012) J. Du et al. BLOOD
- Pharmacologic stabilization of HIF-1 increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation
- (2012) C. E. Forristal et al. BLOOD
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- Predictive factors for poor peripheral blood stem cell mobilization and peak CD34+cell count to guide pre-emptive or immediate rescue mobilization.
- (2012) Juan-Manuel Sancho et al. CYTOTHERAPY
- B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2
- (2012) I. G. Winkler et al. HAEMATOLOGICA
- Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation
- (2012) I G Winkler et al. LEUKEMIA
- How I treat patients who mobilize hematopoietic stem cells poorly
- (2011) L. B. To et al. BLOOD
- Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
- (2010) I. G. Winkler et al. BLOOD
- Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
- (2010) Keiyo Takubo et al. Cell Stem Cell
- Hypoxia mediates low cell-cycle activity and increases the proportion of long-term–reconstituting hematopoietic stem cells during in vitro culture
- (2010) Pernilla Eliasson et al. EXPERIMENTAL HEMATOLOGY
- Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) Regulates Hematopoiesis and Bone Formation In Vivo
- (2010) Yi Shen et al. PLoS One
- CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
- (2009) A. Levoye et al. BLOOD
- Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma
- (2009) John F. DiPersio et al. JOURNAL OF CLINICAL ONCOLOGY
- Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model
- (2009) W. M. Bernhardt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Trafficking Mechanisms of Multipotent Mesenchymal Stem Cells Derived from Human Bone Marrow and Placenta
- (2008) Gary Brooke et al. STEM CELLS AND DEVELOPMENT
- Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition
- (2007) Andreas Robinson et al. GASTROENTEROLOGY
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