A Genetic Variant in the Seed Region of miR-4513 Shows Pleiotropic Effects on Lipid and Glucose Homeostasis, Blood Pressure, and Coronary Artery Disease

ThemiR-19a/bfamily positively regulates cardiomyocyte hypertrophy by targeting atrogin-1 and MuRF-1

(2013) Dong Woo Song et al.   BIOCHEMICAL JOURNAL

microRNAs regulate adipocyte differentiation

(2013) Lin Chen et al.   CELL BIOLOGY INTERNATIONAL

Differential MicroRNA Expression Profiles in Peripheral Arterial Disease

(2013) Philip W. Stather et al.   Circulation-Cardiovascular Genetics

The Rotterdam Study: 2014 objectives and design update

(2013) Albert Hofman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Single-nucleotide polymorphisms inside microRNA target sites influence the susceptibility to type 2 diabetes

(2013) Xu Zhao et al.   JOURNAL OF HUMAN GENETICS

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site

(2012) Kris Richardson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Human 3′ miR-499 Mutation Alters Cardiac mRNA Targeting and Function

(2012) Gerald W. Dorn et al.   CIRCULATION RESEARCH

microRNAs in cancer management

(2012) Yi W Kong et al.   LANCET ONCOLOGY

The association of miR-146a rs2910164 and miR-196a2 rs11614913 polymorphisms with cancer risk: a meta-analysis of 32 studies

(2012) Jianbo Wang et al.   MUTAGENESIS

Functional screening identifies miRNAs inducing cardiac regeneration

(2012) Ana Eulalio et al.   NATURE

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

(2012) Robert A Scott et al.   NATURE GENETICS

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

(2012) Alisa K Manning et al.   NATURE GENETICS

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

(2012) Eva van Rooij et al.   NATURE REVIEWS DRUG DISCOVERY

Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs

(2012) Jingmin Shu et al.   RNA Biology

MicroRNAs: a new ray of hope for diabetes mellitus

(2012) Munish Kumar et al.   Protein & Cell

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

Circulating MicroRNAs

(2011) Stephan Fichtlscherer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice

(2011) A. Meenhuis et al.   BLOOD

Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study)

(2011) Jens K Hertel et al.   BMC Medical Genetics

miRvar: A comprehensive database for genomic variations in microRNAs

(2011) Deeksha Bhartiya et al.   HUMAN MUTATION

Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis

(2011) Jing Gong et al.   HUMAN MUTATION

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

(2011) Louise V Wain et al.   NATURE GENETICS

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs

(2010) D. D. Jima et al.   BLOOD

Association of obesity risk SNPs in PCSK1with insulin sensitivity and proinsulin conversion

(2010) Martin Heni et al.   BMC Medical Genetics

Circulating MicroRNA-208b and MicroRNA-499 Reflect Myocardial Damage in Cardiovascular Disease

(2010) Maarten F. Corsten et al.   Circulation-Cardiovascular Genetics

MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets

(2010) Maxim Barenboim et al.   HUMAN MUTATION

Cohort Profile: The Study of Health in Pomerania

(2010) H. Volzke et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

(2010) Iris M Heid et al.   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

(2010) Richa Saxena et al.   NATURE GENETICS

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

A Genome-Wide Association Study Identifies a Novel Major Locus for Glycemic Control in Type 1 Diabetes, as Measured by Both A1C and Glucose

(2009) A. D. Paterson et al.   DIABETES

Gene-Gene Interactions Among Genetic Variants from Obesity Candidate Genes for Nonobese and Obese Populations in Type 2 Diabetes

(2009) Eugene Lin et al.   Genetic Testing and Molecular Biomarkers

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss

(2009) Ángeles Mencía et al.   NATURE GENETICS

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

(2009) Tomoko Kawamata et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates

(2009) Samuel Hiard et al.   NUCLEIC ACIDS RESEARCH

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

(2008) A. D. Johnson et al.   BIOINFORMATICS

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

(2008) Manuel A R Ferreira et al.   NATURE GENETICS