Genetic and Functional Analyses ofZIC3Variants in Congenital Heart Disease

The phenotypic spectrum ofZIC3mutations includes isolated d-transposition of the great arteries and double outlet right ventricle

(2013) Lisa C.A. D'Alessandro et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Zic3 is required in the migrating primitive streak for node morphogenesis and left-right patterning

(2013) M. J. Sutherland et al.   HUMAN MOLECULAR GENETICS

An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis

(2012) Ashley E. Cast et al.   DEVELOPMENTAL BIOLOGY

Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left–right patterning and heart development

(2012) Zhengxin Jiang et al.   HUMAN MOLECULAR GENETICS

Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice

(2012) Malgorzata E. Quinn et al.   HUMAN MOLECULAR GENETICS

From VACTERL-H to heterotaxy: Variable expressivity of ZIC3-related disorders

(2011) Brian Chung et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Mutations in ZIC3 and ACVR2B are a common cause of heterotaxy and associated cardiovascular anomalies

(2011) Lijiang Ma et al.   CARDIOLOGY IN THE YOUNG

Identification of a Novel ZIC3 Isoform and Mutation Screening in Patients with Heterotaxy and Congenital Heart Disease

(2011) James E. J. Bedard et al.   PLoS One

Situs Inversus Totalis and a NovelZIC3Mutation in a Family with X-linked Heterotaxy

(2011) Lisa C.A. D'Alessandro et al.   Congenital Heart Disease

Far from solved: A perspective on what we know about early mechanisms of left-right asymmetry

(2010) Laura N. Vandenberg et al.   DEVELOPMENTAL DYNAMICS

Polyalanine expansion in the ZIC3 gene leading to X-linked heterotaxy with VACTERL association: a new polyalanine disorder?

(2010) M. W. Wessels et al.   JOURNAL OF MEDICAL GENETICS

The Pluripotency Regulator Zic3 Is a Direct Activator of the Nanog Promoter in ESCs

(2010) Linda Shushan Lim et al.   STEM CELLS

Disorders of left-right asymmetry: Heterotaxy and situs inversus

(2009) Mardi J. Sutherland et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Familial transposition of the great arteries caused by multiple mutations in laterality genes

(2009) A. De Luca et al.   HEART

Molecular mechanisms underlying polyalanine diseases

(2009) C. Messaed et al.   NEUROBIOLOGY OF DISEASE

CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA

(2008) Kumiko Sakai-Kato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain

(2008) Minoru Hatayama et al.   HUMAN MOLECULAR GENETICS