Article
Multidisciplinary Sciences
Monal Yu-Hsuan Chang, Yan-De Liou, Jou-Hsuan Huang, Chia-Hung Su, Shu-Chien Huang, Ming-Tai Lin, Shyh-Jye Chen
Summary: This study aims to introduce the image characteristics of double-chambered right ventricle on cardiac computed tomography and establish a diagnostic criterion. The right ventricular constrictive ratio was found to be a valuable asset for the preoperative diagnosis of double-chambered right ventricle.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Masuelli Sofia, Real Sebastian, Campoy Emanuel, Maria Teresita Branham, Diego Matias Marzese, Salomon Matthew, Gerardo De Blas, Arias Rodolfo, Levin Michael, Roque Maria
Summary: This study discovered differential DNA methylation and bioelectric differences between left-sided and right-sided breast tumors, which were associated with tumor proliferation. These findings provide new targets for future breast cancer therapeutic approaches.
MOLECULAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tilman Emrich, Veronica Bordonaro, U. Joseph Schoepf, Aniela Petrescu, Gabrielle Young, Moritz Halfmann, Theresia Schoeler, Josua Decker, Ibukun Abidoye, Anna Lena Emrich, Karl-Friedrich Kreitner, Kai Helge Schmidt, Akos Varga-Szemes, Aurelio Secinaro
Summary: The study aimed to test the feasibility of T2 mapping for detecting left-to-right shunts. Results indicated that the T2 ratio can serve as an imaging biomarker capable of detecting or ruling out left-to-right shunts.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Neurosciences
Leah T. Johnstone, Emma M. Karlsson, David P. Carey
Summary: Neuroscientific techniques show that left-handers have more unusual cerebral asymmetries for language compared to right-handers, with left-handers demonstrating less lateralization for language, faces, and bodies when they have typical cerebral asymmetries.
Article
Biochemistry & Molecular Biology
Jianguo Wang, Sidi Ma, Peijie Yu, Xionglei He
Summary: The human brain exhibits anatomical symmetry, but also possesses fine-scale structural asymmetries that contribute to distinct functional divisions. Previous studies suggested that these asymmetric structures are primate specific or unique to humans, indicating recent evolution of genes responsible for human brain asymmetry. In our study, we identified over 1,500 traits associated with human brain asymmetry and discovered approximately 200 genes that are predominantly upregulated in brain tissues. Surprisingly, these genes are evolutionarily ancient and show brain-specific upregulation in humans, indicating the role of ancient genes in shaping the structural asymmetry of the human brain over time.
MOLECULAR BIOLOGY AND EVOLUTION
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mari Nieves Velasco Forte, Sebastien Roujol, Bram Ruijsink, Israel Valverde, Phuoc Duong, Nick Byrne, Sascha Krueger, Steffen Weiss, Yousef Arar, Surendranath R. Veeram Reddy, Tobias Schaeffter, Tarique Hussain, Reza Razavi, Kuberan Pushparajah
Summary: The study aimed to evaluate the feasibility of MRI-guided catheterization in young patients with CHD using advanced visualization passive tracking techniques. The results indicated that MRI-guided catheterizations were carried out safely and is feasible in children and adults with CHD. The pSAT sequence offered robust and simultaneous high contrast visualization of the catheter and cardiac anatomy.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Article
Multidisciplinary Sciences
Xin-Xin Fu, Ding-Hao Zhuo, Ying-Jie Zhang, Yun-Fei Li, Xiang Liu, Yan-Yi Xing, Ying Huang, Yi-Fan Wang, Tao Cheng, Dan Wang, Si-Han Chen, Yi-Jian Chen, Guan-Nan Jiang, Fu- Lu, Yu Feng, Xiao Huang, Jun Ma, Wei Liu, Ge Bai, Peng-Fei Xu
Summary: The emergence of left-right (LR) asymmetry in a patterning field along the anterior-posterior axis is still an unresolved problem in developmental biology. This study identifies Follistatin (Fst) as a regulator that restricts the propagation of Nodal ortholog Southpaw (Spaw) in the right lateral plate mesoderm (LPM) and facilitates the establishment of a robust LR asymmetric Nodal patterning. Furthermore, Fst inhibits the Activin-Nodal signaling pathway in the forebrain, contributing to the orderly propagation of asymmetric Nodal activation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Psychology, Biological
Zhiqiang Sha, Dick Schijven, Amaia Carrion-Castillo, Marc Joliot, Bernard Mazoyer, Simon E. Fisher, Fabrice Crivello, Clyde Francks
Summary: Genes associated with brain asymmetry are linked to microtubule-related genes and embryonic brain expression, and have overlap with genetic variants related to autism, educational attainment, and schizophrenia. Left-right hemispheric asymmetry is crucial for healthy brain organization and language functions, but the mechanism behind establishing the human brain's left-right axis remains unidentified.
NATURE HUMAN BEHAVIOUR
(2021)
Article
Cardiac & Cardiovascular Systems
Zarmiga Karunanithi, Mads Jonsson Andersen, Soren Mellemkjaer, Mathias Alstrup, Farhad Waziri, Tor Skibsted Clemmensen, Vibeke Elisabeth Hjortdal, Steen Hvitfeldt Poulsen
Summary: Patients with corrected ASD showed impaired systolic function in both left and right ventricles during exercise, while resting systolic function parameters were normal. Subclinical myocardial dysfunction during exercise may be associated with long-term morbidities in this patient group.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2022)
Article
Acoustics
Greggory R. DeVore, Yalda Afshar, Danielle Harake, Gary Satou, Mark Sklansky
Summary: This study examines fetuses with TOF and evaluates the ventricular contractility and function using speckle-tracking analysis. The results show that LV contractility and function are significantly abnormal in fetuses with TOF, while RV contractility is mostly normal.
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Article
Developmental Biology
Brent H. Wyatt, Nirav M. Amin, Kristen Bagley, Dustin Wcisel, Michael K. Dush, Jeffrey A. Yoder, Nanette M. Nascone-Yoder
Summary: This study reveals the role of single-minded 2 gene in regulating left-right symmetry in the development of frog embryo stomach, further illustrating the importance of laterality factors in morphogenesis.
Article
Cell Biology
Eriko Kajikawa, Toru Miki, Masayoshi Takeda, Hiroshi Kiyonari, Hiroshi Hamada
Summary: The evolutionary diversity of brain left-right asymmetry was examined by studying reptile embryos. The Chinese softshell turtle and the red-eared slider turtle showed left-sided expression of certain genes in the developing forebrain, while this asymmetry was not detected in the Madagascar ground gecko. These findings suggest that brain left-right asymmetry varies even among reptiles.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Teije C. Middelkoop, Julia Garcia-Baucells, Porfirio Quintero-Cadena, Lokesh G. Pimpale, Shahrzad Yazdi, Paul W. Sternberg, Peter Gross, Stephan W. Grill
Summary: This study demonstrates that the active torque generation dependent on CYK-1/Formin plays a crucial role in chiral symmetry breaking of actomyosin flows, driving left-right symmetry breaking in the nematode worm. The activity of Non-Muscle Myosin II, on the other hand, promotes cortical actomyosin flows but is not essential for chiral symmetry breaking.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Naiara Demnitz, Kathrine Skak Madsen, Line K. Johnsen, Michael Kjaer, Carl-Johan Boraxbekk, Hartwig R. Siebner
Summary: The study found that older adults show similar trends of asymmetry in the white matter microstructure of the corticospinal tract and dexterity as adolescents, but to a lesser degree. However, unlike adolescents, there was no evidence of a linear relationship between CST microstructure asymmetry and dexterity in older adults.
Article
Management
Laszlo Csato
Summary: This paper compares the performance of the eigenvalue method and the row geometric mean as two weighting procedures. Through numerical experiments, it is found that the priorities derived from the two eigenvectors in the eigenvalue method do not always agree, while the row geometric mean serves as a compromise between them.
EUROPEAN JOURNAL OF OPERATIONAL RESEARCH
(2024)