First- and second-shell metal binding residues in human proteins are disproportionately associated with disease-related SNPs

Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme

(2010) Jee-Loon Foo et al.   BIOCHEMICAL JOURNAL

Mutation@A Glance: An Integrative Web Application for Analysing Mutations from Human Genetic Diseases

(2010) A. Hijikata et al.   DNA RESEARCH

Using SIFT and PolyPhen to Predict Loss-of-Function and Gain-of-Function Mutations

(2010) Sarah E. Flanagan et al.   Genetic Testing and Molecular Biomarkers

Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

(2010) Sungsam Gong et al.   PLoS One

Conformational changes associated with the binding of zinc acetate at the putative active site ofXcTcmJ, a cupin fromXanthomonas campestrispv.campestris

(2009) Herbert L. Axelrod et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Next generation tools for the annotation of human SNPs

(2009) Rachel Karchin   BRIEFINGS IN BIOINFORMATICS

Advances in translational bioinformatics: computational approaches for the hunting of disease genes

(2009) M. G. Kann   BRIEFINGS IN BIOINFORMATICS

Functional annotations improve the predictive score of human disease-related mutations in proteins

(2009) Remo Calabrese et al.   HUMAN MUTATION

Cancer-associated mutations are preferentially distributed in protein kinase functional sites

(2009) Jose M. G. Izarzugaza et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Small-Molecule Activators of a Proenzyme

(2009) D. W. Wolan et al.   SCIENCE

Approaches and Resources for Prediction of the Effects of Non-Synonymous Single Nucleotide Polymorphism on Protein Function and Interactions

(2008) S. Teng et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Stability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligand

(2008) S. Gordo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of 3D metal binding sites from translated gene sequences based on remote-homology templates

(2008) Ronen Levy et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Evolution of binding sites for zinc and calcium ions playing structural roles

(2007) James W. Torrance et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS