The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of  -synuclein, and enhances its secretion and nuclear localization in cells

Alpha-synuclein mRNA expression in oligodendrocytes in MSA

(2014) Yasmine T. Asi et al.   GLIA

α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy?

(2013) Aoife P. Kiely et al.   ACTA NEUROPATHOLOGICA

G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome

(2013) Suzanne Lesage et al.   ANNALS OF NEUROLOGY

The Parkinson’s Disease-Associated H50Q Mutation Accelerates α-Synuclein Aggregation in Vitro

(2013) Dhiman Ghosh et al.   BIOCHEMISTRY

Nuclear translocation of alpha-synuclein increases susceptibility of MES23.5 cells to oxidative stress

(2013) Ming Zhou et al.   BRAIN RESEARCH

Alpha-synuclein transfers from neurons to oligodendrocytes

(2013) Juan F. Reyes et al.   GLIA

Assessing the Subcellular Dynamics of Alpha-synuclein Using Photoactivation Microscopy

(2013) Susana Gonçalves et al.   MOLECULAR NEUROBIOLOGY

Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease

(2013) Silke Appel-Cresswell et al.   MOVEMENT DISORDERS

The Function of α-Synuclein

(2013) Jacob T. Bendor et al.   NEURON

Polo-like kinase 2 regulates selective autophagic  -synuclein clearance and suppresses its toxicity in vivo

(2013) A. Oueslati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Yeast Reveal a "Druggable" Rsp5/Nedd4 Network that Ameliorates  -Synuclein Toxicity in Neurons

(2013) D. F. Tardiff et al.   SCIENCE

Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson’s disease

(2012) Almas Siddiqui et al.   FREE RADICAL BIOLOGY AND MEDICINE

Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease

(2011) Ivana Devic et al.   BRAIN

E46K Human α-Synuclein Transgenic Mice Develop Lewy-like and Tau Pathology Associated with Age-dependent, Detrimental Motor Impairment

(2011) Kristel L. Emmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequence correction of random coil chemical shifts: correlation between neighbor correction factors and changes in the Ramachandran distribution

(2011) Magnus Kjaergaard et al.   JOURNAL OF BIOMOLECULAR NMR

Authentically Phosphorylated  -Synuclein at Ser129 Accelerates Neurodegeneration in a Rat Model of Familial Parkinson's Disease

(2011) H. Sato et al.   JOURNAL OF NEUROSCIENCE

Determining nuclear localization of alpha-synuclein in mouse brains

(2011) Z. Huang et al.   NEUROSCIENCE

The N-Terminus of the Intrinsically Disordered Protein α-Synuclein Triggers Membrane Binding and Helix Folding

(2010) Tim Bartels et al.   BIOPHYSICAL JOURNAL

The Lipid-binding Domain of Wild Type and Mutant α-Synuclein

(2010) Elka R. Georgieva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alpha-synuclein immunoreactivity in minor salivary gland biopsies of Parkinson's disease patients

(2010) Maria Graciela Cersósimo et al.   MOVEMENT DISORDERS

Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation

(2010) V. L. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson’s Disease Revealed by Solution NMR Spectroscopy

(2009) Christina R. Bodner et al.   BIOCHEMISTRY

Expression and Subcellular Location of Alpha-Synuclein During Mouse-Embryonic Development

(2009) Shan-chuan Zhong et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Phosphorylation of Synucleins by Members of the Polo-like Kinase Family

(2009) Martial K. Mbefo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy

(2009) Christina R. Bodner et al.   JOURNAL OF MOLECULAR BIOLOGY

α-Synuclein and neuronal cell death

(2009) Mark R Cookson   Molecular Neurodegeneration

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

(2009) Esti Yeger-Lotem et al.   NATURE GENETICS

A bright and photostable photoconvertible fluorescent protein

(2009) Sean A McKinney et al.   NATURE METHODS

Nuclear and neuritic distribution of serine-129 phosphorylated α-synuclein in transgenic mice

(2009) H. Schell et al.   NEUROSCIENCE

Alterations in corticostriatal synaptic plasticity in mice overexpressing human α-synuclein

(2009) J.B. Watson et al.   NEUROSCIENCE

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clearance and deposition of extracellular α-synuclein aggregates in microglia

(2008) He-Jin Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Semi-quantitative analysis of α-synuclein in subcellular pools of rat brain neurons: An immunogold electron microscopic study using a C-terminal specific monoclonal antibody

(2008) Ling Zhang et al.   BRAIN RESEARCH

Spin-Label EPR on α-Synuclein Reveals Differences in the Membrane Binding Affinity of the Two Antiparallel Helices

(2008) Malte Drescher et al.   CHEMBIOCHEM

Aggregates Assembled From Overexpression of Wild-Type α-Synuclein are not Toxic to Human Neuronal Cells

(2008) Li-wen Ko et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Membrane-Bound α-Synuclein Forms an Extended Helix: Long-Distance Pulsed ESR Measurements Using Vesicles, Bicelles, and Rodlike Micelles

(2008) Elka R. Georgieva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-produced α-synuclein oligomers are targeted to, and impair, the 26S proteasome

(2008) Evangelia Emmanouilidou et al.   NEUROBIOLOGY OF AGING

Immunolocalization of alpha-synuclein in the rat spinal cord by two novel monoclonal antibodies

(2008) G. Vivacqua et al.   NEUROSCIENCE

Structure of membrane-bound  -synuclein from site-directed spin labeling and computational refinement

(2008) C. C. Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice

(2006) Masaki Wakamatsu et al.   NEUROBIOLOGY OF AGING