Functional analysis of endoglin mutations from hereditary hemorrhagic telangiectasia type 1 patients reveals different mechanisms for endoglin loss of function

Investigation of Endoglin Wild-Type and Missense Mutant Protein Heterodimerisation Using Fluorescence Microscopy Based IF, BiFC and FRET Analyses

(2014) Tassilo Förg et al.   PLoS One

BMP9 Mutations Cause a Vascular-Anomaly Syndrome with Phenotypic Overlap with Hereditary Hemorrhagic Telangiectasia

(2013) Whitney L. Wooderchak-Donahue et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-  signaling pathways

(2013) S. Park et al.   JOURNAL OF CELL SCIENCE

Review: The enigmatic role of endoglin in the placenta

(2013) A.L. Gregory et al.   PLACENTA

Endoglin inhibits ERK-induced c-Myc and cyclin D1 expression to impede endothelial cell proliferation

(2012) Christopher C. Pan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural and Functional Insights into Endoglin Ligand Recognition and Binding

(2012) Aaron Alt et al.   PLoS One

Endoglin Requirement for BMP9 Signaling in Endothelial Cells Reveals New Mechanism of Action for Selective Anti-Endoglin Antibodies

(2012) Olivier Nolan-Stevaux et al.   PLoS One

A novel ENG mutation causing impaired co-translational processing of endoglin associated with hereditary hemorrhagic telangiectasia

(2012) Atsuo Suzuki et al.   THROMBOSIS RESEARCH

Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth

(2011) Roselyne Castonguay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum Quality Control Is Involved in the Mechanism of Endoglin-Mediated Hereditary Haemorrhagic Telangiectasia

(2011) Bassam R. Ali et al.   PLoS One

Functional analysis of the BMP9 response of ALK1 mutants from HHT2 patients: a diagnostic tool for novel ACVRL1 mutations

(2010) N. Ricard et al.   BLOOD

Hereditary haemorrhagic telangiectasia: Pathophysiology, diagnosis and treatment

(2010) Claire L. Shovlin   BLOOD REVIEWS

Update on molecular diagnosis of hereditary hemorrhagic telangiectasia

(2010) Jennifer Richards-Yutz et al.   HUMAN GENETICS

Hereditary hemorrhagic telangiectasia: from molecular biology to patient care

(2010) S. DUPUIS-GIROD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor

(2008) Laurent David et al.   CIRCULATION RESEARCH