Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLDS-mediated axon protection independent of axonal mitochondria

NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins

(2013) Alejandro Ocampo et al.   HUMAN MOLECULAR GENETICS

A Novel Drosophila Model of Nerve Injury Reveals an Essential Role of Nmnat in Maintaining Axonal Integrity

(2012) Yanshan Fang et al.   CURRENT BIOLOGY

WldS Prevents Axon Degeneration through Increased Mitochondrial Flux and Enhanced Mitochondrial Ca2+ Buffering

(2012) Michelle A. Avery et al.   CURRENT BIOLOGY

Axon degeneration: Molecular mechanisms of a self-destruction pathway

(2012) Jack T. Wang et al.   JOURNAL OF CELL BIOLOGY

Mitochondria as a central sensor for axonal degenerative stimuli

(2012) Felipe A. Court et al.   TRENDS IN NEUROSCIENCES

NMNAT suppresses Tau-induced neurodegeneration by promoting clearance of hyperphosphorylated Tau oligomers in a Drosophila model of tauopathy

(2011) Yousuf O. Ali et al.   HUMAN MOLECULAR GENETICS

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Mitochondria: The Next (Neurode)Generation

(2011) Eric A. Schon et al.   NEURON

Patterning Axon Targeting of Olfactory Receptor Neurons by Coupled Hedgehog Signaling at Two Distinct Steps

(2010) Ya-Hui Chou et al.   CELL

Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury

(2010) Xin Xiong et al.   JOURNAL OF CELL BIOLOGY

Mechanisms of acute axonal degeneration in the optic nerve in vivo

(2010) J. Knoferle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial trafficking and morphology in neuronal injury

(2009) Gordon L. Rintoul et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Stimulation of glutamate receptors in cultured hippocampal neurons causes Ca2+-dependent mitochondrial contraction

(2009) Tatiana Brustovetsky et al.   CELL CALCIUM

Patterning and organization of motor neuron dendrites in the Drosophila larva

(2009) Michael D. Kim et al.   DEVELOPMENTAL BIOLOGY

New insights into mitochondrial structure during cell death

(2009) Guy Perkins et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

WldSrequires Nmnat1 enzymatic activity and N16–VCP interactions to suppress Wallerian degeneration

(2009) Michelle A. Avery et al.   JOURNAL OF CELL BIOLOGY

Non-Nuclear WldS Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo

(2009) B. Beirowski et al.   JOURNAL OF NEUROSCIENCE

Nicotinamide Mononucleotide Adenylyltransferase Expression in Mitochondrial Matrix Delays Wallerian Degeneration

(2009) N. Yahata et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

Nicotinamide Mononucleotide Adenylyl Transferase-Mediated Axonal Protection Requires Enzymatic Activity But Not Increased Levels of Neuronal Nicotinamide Adenine Dinucleotide

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

Acute energy restriction triggers Wallerian degeneration in mouse

(2008) Susana Alvarez et al.   EXPERIMENTAL NEUROLOGY

Revealing the anti-HRP epitope in Drosophila and Caenorhabditis

(2008) Katharina Paschinger et al.   GLYCOCONJUGATE JOURNAL

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration

(2008) R. Grace Zhai et al.   NATURE

Mitochondrial fragmentation in neurodegeneration

(2008) Andrew B. Knott et al.   NATURE REVIEWS NEUROSCIENCE