Variants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms

The interactive effect of mortality reminders and tobacco craving on smoking topography.

(2013) Jamie Arndt et al.   HEALTH PSYCHOLOGY

Genetic Variants on 15q25.1, Smoking, and Lung Cancer: An Assessment of Mediation and Interaction

(2012) Tyler J. VanderWeele et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Interplay of Genetic Risk Factors (CHRNA5-CHRNA3-CHRNB4) and Cessation Treatments in Smoking Cessation Success

(2012) Li-Shiun Chen et al.   AMERICAN JOURNAL OF PSYCHIATRY

The updated biology of hypoxia-inducible factor

(2012) Samantha N Greer et al.   EMBO JOURNAL

Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6

(2012) A. Joseph Bloom et al.   HUMAN MOLECULAR GENETICS

Smoking topography and outcome expectancies among individuals with schizotypy

(2012) Diana W. Stewart et al.   PSYCHIATRY RESEARCH

Assessment of smoking behaviour in the dental setting. A study comparing self-reported questionnaire data and exhaled carbon monoxide levels

(2011) Marc Frei et al.   Clinical Oral Investigations

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13

(2011) M. H. Cho et al.   HUMAN MOLECULAR GENETICS

Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins

(2011) Kimberly Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relationship Between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 Variation and Smoking Behaviors and Lung Cancer Risk

(2011) Catherine A. Wassenaar et al.   JNCI-Journal of the National Cancer Institute

Dissection of the Phenotypic and Genotypic Associations With Nicotinic Dependence

(2011) Li-Shiun Chen et al.   NICOTINE & TOBACCO RESEARCH

The Reliability of Puff Topography and Subjective Responses During Ad lib Smoking of a Single Cigarette

(2011) K. A. Perkins et al.   NICOTINE & TOBACCO RESEARCH

The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European–Americans

(2011) Joseph Bloom et al.   Pharmacogenetics and Genomics

Genetic Variation in Nicotine Metabolism Predicts the Efficacy of Extended-Duration Transdermal Nicotine Therapy

(2010) C Lerman et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Carbon Monoxide Promotes VEGF Expression by Increasing HIF-1α Protein Level via Two Distinct Mechanisms, Translational Activation and Stabilization of HIF-1α Protein

(2010) Yoon Kyung Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

A Randomized Placebo-Controlled Clinical Trial of 5 Smoking Cessation Pharmacotherapies

(2009) Megan E. Piper et al.   ARCHIVES OF GENERAL PSYCHIATRY

Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase

(2009) Qing Zhang et al.   CANCER CELL

Utility and Relationships of Biomarkers of Smoking in African-American Light Smokers

(2009) M. K. Ho et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

(2009) N. L. Saccone et al.   CANCER RESEARCH

Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing

(2009) James D. Webb et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy

(2009) Rachel M. Freathy et al.   HUMAN MOLECULAR GENETICS

Breath carbon monoxide and semiquantitative saliva cotinine as biomarkers for smoking

(2009) Gina F. Marrone et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways

(2009) A. Siddiq et al.   JOURNAL OF NEUROSCIENCE

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

(2008) Laura Jean Bierut et al.   AMERICAN JOURNAL OF PSYCHIATRY

Smokers with the CHRNA Lung Cancer-Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

(2008) L. Le Marchand et al.   CANCER RESEARCH

Toward Personalized Therapy for Smoking Cessation: A Randomized Placebo-controlled Trial of Bupropion

(2008) F Patterson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

(2008) Julián Aragonés et al.   NATURE GENETICS

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

A randomized controlled clinical trial of bupropion SR and individual smoking cessation counseling

(2008) Danielle McCarthy et al.   NICOTINE & TOBACCO RESEARCH

Nicotine metabolic rate predicts successful smoking cessation with transdermal nicotine: A validation study

(2008) Robert A. Schnoll et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR