Identification of FHL1 as a therapeutic target for Duchenne muscular dystrophy

Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics

(2013) A. Amirouche et al.   HUMAN MOLECULAR GENETICS

Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice

(2013) Andrea A. Domenighetti et al.   HUMAN MOLECULAR GENETICS

Emerging drugs for Duchenne muscular dystrophy

(2012) Vinod Malik et al.   EXPERT OPINION ON EMERGING DRUGS

Evidence for FHL1 as a novel disease gene for isolated hypertrophic cardiomyopathy

(2012) Felix W. Friedrich et al.   HUMAN MOLECULAR GENETICS

IGF-1 induces IP3-dependent calcium signal involved in the regulation of myostatin gene expression mediated by NFAT during myoblast differentiation

(2012) Juan A. Valdés et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

(2012) Stefan M. Gehrig et al.   NATURE

Sphingosine-1-Phosphate Enhances Satellite Cell Activation in Dystrophic Muscles through a S1PR2/STAT3 Signaling Pathway

(2012) Kenneth C. Loh et al.   PLoS One

Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice

(2011) M. H. Kim et al.   HUMAN MOLECULAR GENETICS

Inherited neuromuscular disorders: Pathway to diagnosis

(2011) Manoj P Menezes et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Four and a half LIM protein 1 gene mutations cause four distinct human myopathies: A comprehensive review of the clinical, histological and pathological features

(2011) Belinda S. Cowling et al.   NEUROMUSCULAR DISORDERS

Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype

(2010) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice

(2010) A. R. Amenta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making Fast-Twitch Dystrophic Muscles Bigger Protects Them from Contraction Injury and Attenuates the Dystrophic Pathology

(2009) Stefan M. Gehrig et al.   AMERICAN JOURNAL OF PATHOLOGY

Stimulation of calcineurin Aα activity attenuates muscle pathophysiology in mdx dystrophic mice

(2008) Nicole Stupka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Akt activation prevents the force drop induced by eccentric contractions in dystrophin-deficient skeletal muscle

(2008) Bert Blaauw et al.   HUMAN MOLECULAR GENETICS

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

Sarcospan reduces dystrophic pathology: stabilization of the utrophin–glycoprotein complex

(2008) Angela K. Peter et al.   JOURNAL OF CELL BIOLOGY

Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy

(2008) Belinda S. Cowling et al.   JOURNAL OF CELL BIOLOGY

Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy

(2008) Miranda D. Grounds et al.   NEUROBIOLOGY OF DISEASE

Reduced muscle necrosis and long-term benefits in dystrophic mdx mice after cV1q (blockade of TNF) treatment

(2008) Hannah G. Radley et al.   NEUROMUSCULAR DISORDERS