Evidence for FHL1 as a novel disease gene for isolated hypertrophic cardiomyopathy

Defective proteolytic systems in Mybpc3-targeted mice with cardiac hypertrophy

(2011) Saskia Schlossarek et al.   BASIC RESEARCH IN CARDIOLOGY

Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function

(2011) Sabine J. van Dijk et al.   Circulation-Heart Failure

The ubiquitin–proteasome system in cardiomyopathies

(2011) Saskia Schlossarek et al.   CURRENT OPINION IN CARDIOLOGY

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities

(2011) Saskia Schlossarek et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy

(2011) Bernard J. Gersh et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Four and a half LIM protein 1 gene mutations cause four distinct human myopathies: A comprehensive review of the clinical, histological and pathological features

(2011) Belinda S. Cowling et al.   NEUROMUSCULAR DISORDERS

Human Engineered Heart Tissue as a Versatile Tool in Basic Research and Preclinical Toxicology

(2011) Sebastian Schaaf et al.   PLoS One

Proteasome functional insufficiency activates the calcineurin–NFAT pathway in cardiomyocytes and promotes maladaptive remodelling of stressed mouse hearts

(2010) Mingxin Tang et al.   CARDIOVASCULAR RESEARCH

Ubiquitin Proteasome Dysfunction in Human Hypertrophic and Dilated Cardiomyopathies

(2010) Jaime M. Predmore et al.   CIRCULATION

Development of a Drug Screening Platform Based on Engineered Heart Tissue

(2010) Arne Hansen et al.   CIRCULATION RESEARCH

A novel mutation in FHL1 in a family with X-linked scapuloperoneal myopathy: Phenotypic spectrum and structural study of FHL1 mutations

(2010) Dong-Hui Chen et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Familial Reducing Body Myopathy with Cytoplasmic Bodies and Rigid Spine Revisited: Identification of a Second LIM Domain Mutation in FHL1

(2010) J. Schessl et al.   NEUROPEDIATRICS

Mutations of the FHL1 Gene Cause Emery-Dreifuss Muscular Dystrophy

(2009) Lucie Gueneau et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Contractures and hypertrophic cardiomyopathy in a novel FHL1 mutation

(2009) Hans Knoblauch et al.   ANNALS OF NEUROLOGY

Clinical, histological and genetic characterization of reducing body myopathy caused by mutations in FHL1

(2009) Joachim Schessl et al.   BRAIN

The ubiquitin-proteasome system in cardiac proteinopathy: a quality control perspective

(2009) H. Su et al.   CARDIOVASCULAR RESEARCH

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

(2009) Giulia Mearini et al.   CARDIOVASCULAR RESEARCH

Cardiac Myosin-Binding Protein C Mutations and Hypertrophic Cardiomyopathy

(2009) Sabine J. van Dijk et al.   CIRCULATION

Novel LAMP-2 Mutation in a Family With Danon Disease Presenting With Hypertrophic Cardiomyopathy

(2009) Nobuhiro Dougu et al.   CIRCULATION JOURNAL

Nonsense-Mediated mRNA Decay and Ubiquitin–Proteasome System Regulate Cardiac Myosin-Binding Protein C Mutant Levels in Cardiomyopathic Mice

(2009) Nicolas Vignier et al.   CIRCULATION RESEARCH

A new polymorphism in human calmodulin III gene promoter is a potential modifier gene for familial hypertrophic cardiomyopathy

(2009) F. W. Friedrich et al.   EUROPEAN HEART JOURNAL

Distinct Sarcomeric Substrates Are Responsible for Protein Kinase D-mediated Regulation of Cardiac Myofilament Ca2+Sensitivity and Cross-bridge Cycling

(2009) Sonya C. Bardswell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOVEL FHL1 MUTATIONS IN FATAL AND BENIGN REDUCING BODY MYOPATHY

(2009) S. Shalaby et al.   NEUROLOGY

Consequences of mutations within the C terminus of the FHL1 gene

(2009) B. Schoser et al.   NEUROLOGY

X-Linked Dominant Scapuloperoneal Myopathy Is Due to a Mutation in the Gene Encoding Four-and-a-Half-LIM Protein 1

(2008) Catarina M. Quinzii et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An X-Linked Myopathy with Postural Muscle Atrophy and Generalized Hypertrophy, Termed XMPMA, Is Caused by Mutations in FHL1

(2008) Christian Windpassinger et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The ubiquitin–proteasome system in cardiac dysfunction

(2008) Giulia Mearini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Four and a half LIM protein 1: a partner for KCNA5 in human atrium

(2008) Z. Yang et al.   CARDIOVASCULAR RESEARCH

Fhl-1, a New Key Protein in Pulmonary Hypertension

(2008) Grazyna Kwapiszewska et al.   CIRCULATION

Augmentation of AAV-mediated cardiac gene transfer after systemic administration in adult rats

(2008) O J Müller et al.   GENE THERAPY

Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy

(2008) Belinda S. Cowling et al.   JOURNAL OF CELL BIOLOGY

An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice

(2008) Farah Sheikh et al.   JOURNAL OF CLINICAL INVESTIGATION

Ubiquitin-Proteasome System Impairment Caused by a Missense Cardiac Myosin-binding Protein C Mutation and Associated with Cardiac Dysfunction in Hypertrophic Cardiomyopathy

(2008) Udin Bahrudin et al.   JOURNAL OF MOLECULAR BIOLOGY

Rigid spine syndrome caused by a novel mutation in four-and-a-half LIM domain 1 gene (FHL1)

(2008) Sherine Shalaby et al.   NEUROMUSCULAR DISORDERS