Defining the action spectrum of potential PGC-1α activators on a mitochondrial and cellular level in vivo

Lysine acetylation: enzymes, bromodomains and links to different diseases: Figure 1.

(2014) Linya You et al.   Essays in Biochemistry

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

(2013) Sara Cogliati et al.   CELL

AICAR inhibits oxygen consumption by intact skeletal muscle cells in culture

(2013) Espen E. Spangenburg et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease - A historical prospective

(2013) Hemda Schmilovitz-Weiss et al.   Lipids in Health and Disease

Regulation of mitochondrial biogenesis and PGC-1α under cellular stress

(2013) Tina Wenz   MITOCHONDRION

Nutrient Sensing, Metabolism, and Cell Growth Control

(2013) Hai-Xin Yuan et al.   MOLECULAR CELL

Peroxisome Proliferator-Activated Receptor (PPAR) γ and PPARα Agonists Modulate Mitochondrial Fusion-Fission Dynamics: Relevance to Reactive Oxygen Species (ROS)-Related Neurodegenerative Disorders?

(2013) Juan M. Zolezzi et al.   PLoS One

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

(2013) E. Lapuente-Brun et al.   SCIENCE

Effects of Resveratrol and SIRT1 on PGC-1α Activity and Mitochondrial Biogenesis: A Reevaluation

(2013) Kazuhiko Higashida et al.   PLOS BIOLOGY

Chronic Metformin Associated Cardioprotection Against Infarction: Not Just a Glucose Lowering Phenomenon

(2012) Hannah J. Whittington et al.   CARDIOVASCULAR DRUGS AND THERAPY

Supersizing the Mitochondrial Respiratory Chain

(2012) Eric A. Shoubridge   Cell Metabolism

Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice

(2012) Magali Dumont et al.   HUMAN MOLECULAR GENETICS

Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse

(2012) Lloye M. Dillon et al.   HUMAN MOLECULAR GENETICS

Mitochondrial Protein Acylation and Intermediary Metabolism: Regulation by Sirtuins and Implications for Metabolic Disease

(2012) John C. Newman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RETRACTED: Bezafibrate improves mitochondrial function in the CNS of a mouse model of mitochondrial encephalopathy

(2012) Natalie Noe et al.   MITOCHONDRION

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Increase in Muscle Mitochondrial Biogenesis Does Not Prevent Muscle Loss but Increased Tumor Size in a Mouse Model of Acute Cancer-Induced Cachexia

(2012) Xiao Wang et al.   PLoS One

Long-Term Bezafibrate Treatment Improves Skin and Spleen Phenotypes of the mtDNA Mutator Mouse

(2012) Lloye M. Dillon et al.   PLoS One

Transcriptional integration of mitochondrial biogenesis

(2012) Richard C. Scarpulla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding

(2012) Sudhakaran Prabakaran et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Nucleus-encoded regulators of mitochondrial function: Integration of respiratory chain expression, nutrient sensing and metabolic stress

(2011) Richard C. Scarpulla   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis

(2011) Carlo Viscomi et al.   Cell Metabolism

Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease

(2011) Ashu Johri et al.   HUMAN MOLECULAR GENETICS

Effect of bezafibrate treatment on late-onset mitochondrial myopathy in mice

(2011) Shuichi Yatsuga et al.   HUMAN MOLECULAR GENETICS

Increases in mitochondrial biogenesis impair carcinogenesis at multiple levels

(2011) Xiao Wang et al.   Molecular Oncology

Screening for Active Small Molecules in Mitochondrial Complex I Deficient Patient's Fibroblasts, Reveals AICAR as the Most Beneficial Compound

(2011) Anna Golubitzky et al.   PLoS One

Mitochondrial shape changes: orchestrating cell pathophysiology

(2010) Silvia Campello et al.   EMBO REPORTS

A metabolic shift induced by a PPAR panagonist markedly reduces the effects of pathogenic mitochondrial tRNA mutations

(2010) Tina Wenz et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PGC-1α/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders

(2009) Sarika Srivastava et al.   HUMAN MOLECULAR GENETICS

PGC-1α activation as a therapeutic approach in mitochondrial disease

(2009) Tina Wenz   IUBMB LIFE

Endurance exercise is protective for mice with mitochondrial myopathy

(2009) Tina Wenz et al.   JOURNAL OF APPLIED PHYSIOLOGY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Disorders in the Nervous System

(2008) Salvatore DiMauro et al.   Annual Review of Neuroscience

RETRACTED: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype

(2008) Tina Wenz et al.   Cell Metabolism

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research

(2008) Yuen-Ting Cheung et al.   NEUROTOXICOLOGY

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS