Reduced adiponectin signaling due to weight gain results in nonalcoholic steatohepatitis through impaired mitochondrial biogenesis

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What is the role of adiponectin in obesity related non-alcoholic fatty liver disease?

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Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis

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The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease

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Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition

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Lipotoxicity and steatohepatitis in an overfed mouse model for non-alcoholic fatty liver disease

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Nonalcoholic steatohepatitis

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Hepatic Free Cholesterol Accumulates in Obese, Diabetic Mice and Causes Nonalcoholic Steatohepatitis

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Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet

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Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis

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Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1

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(2010) Elizabeth M. Brunt   Nature Reviews Gastroenterology & Hepatology

Protective roles of adiponectin in obesity-related fatty liver diseases: mechanisms and therapeutic implications

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Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization

(2009) Juichi Fukushima et al.   HEPATOLOGY RESEARCH

Adiponectin knockout mice on high fat diet develop fibrosing steatohepatitis

(2009) Takeharu Asano et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Roles of adipose restriction and metabolic factors in progression of steatosis to steatohepatitis in obese, diabetic mice

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Effect of dietary fat to produce non-alcoholic fatty liver in the rat

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Leptin Contributes to the Adaptive Responses of Mice to High-Fat Diet Intake through Suppressing the Lipogenic Pathway

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Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice

(2008) Kengo Tomita et al.   HEPATOLOGY

Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury

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A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet

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