Constitutive Notch2 signaling induces hepatic tumors in mice

Expression features of SOX9 associate with tumor progression and poor prognosis of hepatocellular carcinoma

(2012) Xiaodong Guo et al.   Diagnostic Pathology

Disruption of Notch1 Induces Vascular Remodeling, Intussusceptive Angiogenesis, and Angiosarcomas in Livers of Mice

(2012) Michael T. Dill et al.   GASTROENTEROLOGY

Phenotypic fidelity (or not?) of epithelial cells in the liver

(2012) George K. Michalopoulos   HEPATOLOGY

A Modified RMCE-Compatible Rosa26 Locus for the Expression of Transgenes from Exogenous Promoters

(2012) Jan S. Tchorz et al.   PLoS One

Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry

(2012) J S Tchorz et al.   Cell Death & Disease

AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2,

(2011) Coral Ho et al.   HEPATOLOGY

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway

(2011) Patrick Viatour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Notch in T-ALL: new players in a complex disease

(2011) Ute Koch et al.   TRENDS IN IMMUNOLOGY

Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice

(2010) Kristina Aleksic et al.   HEPATOLOGY

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

Central Role of c-Myc during Malignant Conversion in Human Hepatocarcinogenesis

(2009) P. Kaposi-Novak et al.   CANCER RESEARCH

Identification of Potential Driver Genes in Human Liver Carcinoma by Genomewide Screening

(2009) H. G. Woo et al.   CANCER RESEARCH

Notch signaling controls liver development by regulating biliary differentiation

(2009) Y. Zong et al.   DEVELOPMENT

Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice

(2009) Erin E. Sparks et al.   HEPATOLOGY

Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice

(2009) Jan S. Tchorz et al.   HEPATOLOGY

Clinical Significance of Cell Cycle–and Apoptosis-Related Markers in Biliary Tract Cancer

(2008) Eva Karamitopoulou et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Cholangiocarcinoma

(2008) Boris R.A. Blechacz et al.   Clinics in Liver Disease

Notch signaling in bile duct development: New insights raise new questions

(2008) Frederic P. Lemaigre   HEPATOLOGY

Cholangiocarcinoma: Advances in pathogenesis, diagnosis, and treatment

(2008) Boris Blechacz et al.   HEPATOLOGY

Liver-specific inactivation ofNotch2, but notNotch1, compromises intrahepatic bile duct development in mice

(2008) Fabian Geisler et al.   HEPATOLOGY

Tumor-specific marker genes for intrahepatic cholangiocarcinoma: Utility and mechanistic insight

(2008) Boris Blechacz et al.   JOURNAL OF HEPATOLOGY