Desmosterol in human nonalcoholic steatohepatitis

Increased Hepatic Synthesis and Dysregulation of Cholesterol Metabolism Is Associated with the Severity of Nonalcoholic Fatty Liver Disease

(2012) Hae-Ki Min et al.   Cell Metabolism

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

(2012) Naga Chalasani et al.   GASTROENTEROLOGY

Lipid Metabolite Profiling Identifies Desmosterol Metabolism as a New Antiviral Target for Hepatitis C Virus

(2012) Mary A. Rodgers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Effects of 34 Risk Loci for Type 2 Diabetes or Hyperglycemia on Lipoprotein Subclasses and Their Composition in 6,580 Nondiabetic Finnish Men

(2011) A. Stancakova et al.   DIABETES

Hepatic Free Cholesterol Accumulates in Obese, Diabetic Mice and Causes Nonalcoholic Steatohepatitis

(2011) Derrick M. Van Rooyen et al.   GASTROENTEROLOGY

Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans

(2011) Jussi Pihlajamäki et al.   JOURNAL OF HEPATOLOGY

The role of serum non-cholesterol sterols as surrogate markers of absolute cholesterol synthesis and absorption

(2011) T.A. Miettinen et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Liver Fat in the Pathogenesis of Insulin Resistance and Type 2 Diabetes

(2010) Hannele Yki-Järvinen   DIGESTIVE DISEASES

Cholesterol synthesis is increased and absorption decreased in non-alcoholic fatty liver disease independent of obesity

(2010) Piia Simonen et al.   JOURNAL OF HEPATOLOGY

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study

(2010) Helena Gylling et al.   JOURNAL OF LIPID RESEARCH

Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Δ24-reductase-deficient cell line

(2009) Sara Rodríguez-Acebes et al.   BIOCHEMICAL JOURNAL

Decreased survival of subjects with elevated liver function tests during a 28-year follow-up

(2009) Cecilia Söderberg et al.   HEPATOLOGY

Hepatitis C Virus Impairs p53 via Persistent Overexpression of 3β-Hydroxysterol Δ24-Reductase

(2009) Tomohiro Nishimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH

(2009) Francisco Caballero et al.   JOURNAL OF HEPATOLOGY

Non-alcoholic fatty liver disease from pathogenesis to management: an update

(2009) G. Musso et al.   Obesity Reviews

3β-Hydroxysteroid-Δ24 Reductase Is a Hydrogen Peroxide Scavenger, Protecting Cells from Oxidative Stress-Induced Apoptosis

(2008) Xiuli Lu et al.   ENDOCRINOLOGY

Liver, Muscle, and Adipose Tissue Insulin Action Is Directly Related to Intrahepatic Triglyceride Content in Obese Subjects

(2008) Kevin M. Korenblat et al.   GASTROENTEROLOGY

Dysmetabolic changes associated with HCV: a distinct syndrome?

(2008) Amedeo Lonardo et al.   Internal and Emergency Medicine

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes

(2007) Piia Simonen et al.   ATHEROSCLEROSIS