Application of GFP imaging in cancer

Invading cancer cells are predominantly in G0/G1resulting in chemoresistance demonstrated by real-time FUCCI imaging

(2014) Shuya Yano et al.   CELL CYCLE

Spatial–temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness

(2014) Shuya Yano et al.   CELL CYCLE

Leptin Receptor Makes Its Mark on MSCs

(2014) Yumi Matsuzaki et al.   Cell Stem Cell

3-Dimensional Tissue Is Formed From Cancer Cells In Vitro on Gelfoam®, But Not on MatrigelTM

(2014) Yasunori Tome et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer

(2014) Weg M. Ongkeko et al.   PLoS One

Fluorescence-Guided Surgery in Combination with UVC Irradiation Cures Metastatic Human Pancreatic Cancer in Orthotopic Mouse Models

(2014) Yukihiko Hiroshima et al.   PLoS One

Novel Modeling of Cancer Cell Signaling Pathways Enables Systematic Drug Repositioning for Distinct Breast Cancer Metastases

(2013) H. Zhao et al.   CANCER RESEARCH

A Genetically Engineered Oncolytic Adenovirus Decoys and Lethally Traps Quiescent Cancer Stem-like Cells in S/G2/M Phases

(2013) S. Yano et al.   CLINICAL CANCER RESEARCH

The proinflammatory peptide substance P promotes blood-brain barrier breaching by breast cancer cells through changes in microvascular endothelial cell tight junctions

(2013) Pedro L. Rodriguez et al.   INTERNATIONAL JOURNAL OF CANCER

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Hand-held high-resolution fluorescence imaging system for fluorescence-guided surgery of patient and cell-line pancreatic tumors growing orthotopically in nude mice

(2013) Yukihiko Hiroshima et al.   JOURNAL OF SURGICAL RESEARCH

Functional role of endothelial adhesion molecules in the early stages of brain metastasis

(2013) Manuel Sarmiento Soto et al.   NEURO-ONCOLOGY

In Vivo Fluorescence Imaging Reveals the Promotion of Mammary Tumorigenesis by Mesenchymal Stromal Cells

(2013) Chien-Chih Ke et al.   PLoS One

Illuminating Cancer Systems with Genetically Engineered Mouse Models and Coupled Luciferase Reporters In Vivo

(2013) Brandon Kocher et al.   Cancer Discovery

Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models

(2012) Atsushi Suetsugu et al.   ADVANCED DRUG DELIVERY REVIEWS

Bioluminescent system for dynamic imaging of cell and animal behavior

(2012) Chikako Hara-Miyauchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens

(2012) Atsushi Suetsugu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Imaging the efficacy of UVC irradiation on superficial brain tumors and metastasis in live mice at the subcellular level

(2012) Masashi Momiyama et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Intravital Microscopy Through an Abdominal Imaging Window Reveals a Pre-Micrometastasis Stage During Liver Metastasis

(2012) L. Ritsma et al.   Science Translational Medicine

The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models

(2011) Hong Zhao et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumor-selective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection

(2011) Hiroyuki Kishimoto et al.   CELL CYCLE

Isolation and Characterization of a Metastatic Hybrid Cell Line Generated by ER Negative and ER Positive Breast Cancer Cells in Mouse Bone Marrow

(2011) Keya De Mukhopadhyay et al.   PLoS One

Transdifferentiation of glioblastoma cells into vascular endothelial cells

(2011) Y. Soda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glowing Tumors Make for Better Detection and Resection

(2011) M. Bouvet et al.   Science Translational Medicine

Simultaneous color-coded imaging to distinguish cancer “stem-like” and non-stem cells in the same tumor

(2010) Atsushi Suetsugu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Imaging the recruitment of cancer-associated fibroblasts by liver-metastatic colon cancer

(2010) Atsushi Suetsugu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Metronomic Gemcitabine in Combination with Sunitinib Inhibits Multisite Metastasis and Increases Survival in an Orthotopic Model of Pancreatic Cancer

(2010) H. S. Tran Cao et al.   MOLECULAR CANCER THERAPEUTICS

Fluorescent Proteins and Their Applications in Imaging Living Cells and Tissues

(2010) Dmitriy M. Chudakov et al.   PHYSIOLOGICAL REVIEWS

Malignant cells facilitate lung metastasis by bringing their own soil

(2010) D. G. Duda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of gastric carcinoma-associated MG7-Ag by serum immuno-PCR assay in a high-risk Chinese population, with implication for screening

(2009) Lian Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

In vivo gene transfer between interacting human osteosarcoma cell lines is associated with acquisition of enhanced metastatic potential

(2009) Yasunori Tome et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A simple biological imaging system for detecting viable human circulating tumor cells

(2009) Toru Kojima et al.   JOURNAL OF CLINICAL INVESTIGATION

Real-time imaging reveals the single steps of brain metastasis formation

(2009) Yvonne Kienast et al.   NATURE MEDICINE

In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation

(2009) H. Kishimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Cancer Metastasis by Cyclophosphamide Pretreatment of Host Mice: An Opposite Effect of Chemotherapy

(2008) K. Yamauchi et al.   CANCER RESEARCH

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

A color-coded orthotopic nude-mouse treatment model of brain-metastatic paralyzing spinal cord cancer that induces angiogenesis and neurogenesis

(2008) K.  Hayashi et al.   CELL PROLIFERATION

A transgenic red fluorescent protein-expressing nude mouse for color-coded imaging of the tumor microenvironment

(2008) Meng Yang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY