Review
Orthopedics
Dean Owyang, Ali Bakhsh, David Brewer, Oliver R. Boughton, Justin P. Cobb
Summary: This systematic review assessed the prevalence, extent, and quality of patient and public involvement (PPI) in orthopaedic surgery RCTs, revealing that there is room for improvement in both the quantity and quality of PPI reporting. Factors contributing to inadequate PPI reporting include a lack of systematic uptake of PPI guidelines and a lack of compulsory PPI reporting from publishing bodies.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Hospitality, Leisure, Sport & Tourism
David Tod, Andrew Booth, Brett Smith
Summary: This article aims to define critical appraisal, discuss its benefits, address conceptual issues affecting the adequacy of appraisal, and provide procedures for reviewers to conduct critical appraisals. Critical appraisal involves assessing a study's trustworthiness or methodological rigor to determine the confidence in its findings. Reviewers need to differentiate between quality and bias, understand total quality scores, weigh the pros and cons of standardized checklists, consider the experimental hierarchy of evidence, distinguish between appraisal tools and reporting standards, and handle the challenges of appraising qualitative research.
INTERNATIONAL REVIEW OF SPORT AND EXERCISE PSYCHOLOGY
(2022)
Article
Multidisciplinary Sciences
Sami Ullah Bhat, Shahid Ahmad Dar, Aadil Hamid
Summary: This paper examines the water quality of springs in Kashmir valley and finds that while some springs have poor water quality, a significant proportion of them are suitable for drinking purposes. The study provides insights for relevant departments and suggests that springs have the potential to meet the rising demand for drinking water, calling for their protection and management.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Sofia Tejada, Sergio Ramirez-Estrada, Alexandre M. Tejo, Carlos G. Forero, Xavier Pomares, Miguel Gallego, Joan B. Soriano, James D. Chalmers, Jordi Rello
Summary: This study evaluated the quality of evidence supporting recommendations in international guidelines on bronchiectasis in adults, and found that newer guidelines had higher quality ratings. However, more high-quality evidence is still needed. The assessment identified four guidelines that were recommended for use, with the highest scores in the domains of scope and purpose.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Francesco Cavallieri, Valentina Fioravanti, Francesco Bove, Eleonora Del Prete, Sara Meoni, Sara Grisanti, Marialuisa Zedde, Rosario Pascarella, Elena Moro, Franco Valzania
Summary: This review summarizes the clinical, biological, and neuroimaging features of COVID-19-related parkinsonism and discusses the possible pathophysiological mechanisms. The appearance of parkinsonism during or immediately after COVID-19 infection is a very rare event. Different mechanisms, including vascular damage and neuroinflammation, may play a role, and further long-term observational studies are needed to evaluate the association between COVID-19 infection and the development of Parkinson's Disease.
Letter
Oncology
Bernhard Horsthemke
Summary: Modern epigenetics has rapidly developed in the past 40 years, but has also been accompanied by misconceptions and methodological shortcomings. One misconception is that chromatin modifications are an independent layer of gene regulation directly responsive to the environment, while in reality, environmental factors mainly affect gene expression through transcription factors and signaling cascades. Methodological shortcomings, such as insufficient consideration of genetic variation and cell mixture distribution, also need to be addressed.
CLINICAL EPIGENETICS
(2022)
Article
Plant Sciences
Hui Zhou, Hongmei Zhu, Yongliang Jia
Summary: This study critically appraised the quality of randomized controlled trials (RCTs) investigating the efficacy and safety of traditional Chinese medicines (TCM) for COVID-19. The overall quality of the included RCTs was found to be substandard, especially for those published in Chinese journals. Further improvements are needed to enhance the reliability and accuracy of future studies.
Article
Gerontology
Kalisha Bonds, MinKyoung Song, Carol J. Whitlatch, Karen S. Lyons, Jeffrey A. Kaye, Christopher S. Lee
Summary: The study found a relationship between appraisal of decision-making involvement and quality of life in African American dementia dyads, identifying three distinct patterns. PLWDs in the Congruent, PLWD High Involvement pattern were younger and had less cognitive impairment, while those in Incongruent patterns showed significant differences in quality of life. Further strategies may be needed to improve the quality of life for PLWDs in different appraisal patterns.
Article
Health Care Sciences & Services
Marc Raynaud, Huanxi Zhang, Kevin Louis, Valentin Goutaudier, Jiali Wang, Quentin Dubourg, Yongcheng Wei, Zeynep Demir, Charlotte Debiais, Olivier Aubert, Yassine Bouatou, Carmen Lefaucheur, Patricia Jabre, Longshan Liu, Changxi Wang, Xavier Jouven, Peter Reese, Jean-Philippe Empana, Alexandre Loupy
Summary: This study reviewed and categorized a large number of medical research related to COVID-19, finding that the majority of research consists of publications without original data, while peer-reviewed original articles with data showed a high risk of bias and included a limited number of patients.
BMC MEDICAL RESEARCH METHODOLOGY
(2021)
Article
Medicine, General & Internal
Yosuke Hatakeyama, Kanako Seto, Ryo Onishi, Koki Hirata, Kunichika Matsumoto, Yinghui Wu, Tomonori Hasegawa
Summary: This study aims to evaluate whether involving methodological experts can improve the quality of clinical practice guidelines (CPGs) after adjusting for other factors. The quality of Japanese CPGs published from 2011 to 2019 was assessed using the AGREE II instrument, and a questionnaire survey targeting CPG development groups was conducted. The results showed a significant association between the involvement of methodological experts and the quality of CPGs.
Article
Engineering, Industrial
Hanna Koskinen, Jari Laarni, Joakim Bergroth
Summary: This paper discusses the importance of expert users' involvement and opinions in the design of complex systems through analyzing a real-life example. The interaction between users and designers is often built around concrete design artifacts and takes place in the later phases of design. However, user involvement often lacks depth and rigor, which hinders critical reflection on work activity and envisioning the overall vision for future work.
INTERNATIONAL JOURNAL OF INDUSTRIAL ERGONOMICS
(2022)
Article
Green & Sustainable Science & Technology
Samuele Lo Piano, Lorenzo Benini
Summary: This study provides a review of approaches for uncertainty appraisal in the life cycle assessment literature. The findings suggest that uncertainty is only appraised in a few studies, with a focus on the life cycle inventory phase. The phases of goal and scope definition and life cycle impact assessment receive less attention. In addition, the study identifies the need for improvement in the appraisal of epistemic uncertainty and the correct definition of probability distribution of uncertain factors.
JOURNAL OF INDUSTRIAL ECOLOGY
(2022)
Article
Pediatrics
Kamal Kumar Singhal, Joseph L. Mathew, Jeanne M. Dsouza, Surbhi Agrawal, Ipsa Kutlehrria, Meenu Singh
Summary: This study aimed to assess the methodological quality of pediatric guidelines for COVID-19 management in India. The study found that the available guidelines have low methodological quality, particularly in terms of methodological rigor. There was diversity in the quality of different aspects of the guidelines. There were no significant differences in the quality of Indian vs. foreign guidelines, updated vs. original versions, and guidelines developed earlier vs. later in the pandemic.
INDIAN JOURNAL OF PEDIATRICS
(2022)
Review
Oncology
Davide De Cicco, Gianpaolo Tartaro, Fortunato Ciardiello, Morena Fasano, Raffaele Rauso, Francesca Fiore, Chiara Spuntarelli, Antonio Troiano, Giorgio Lo Giudice, Giuseppe Colella
Summary: The study reviewed the literature to identify sources of bias encountered in correlating HRQOL with patient-specific or disease/treatment-specific aspects. Recommendations were provided to enhance future study evidence.
Article
Health Care Sciences & Services
Ruzica Bojcic, Mate Todoric, Livia Puljak
Summary: This study analyzed the usage of AMSTAR and AMSTAR 2 in articles published from 2018 to 2020 and explored the reasons and barriers for not using AMSTAR 2. The results showed that even though AMSTAR 2 is an updated version, 44% of the authors still used the old version. However, the use of AMSTAR has been declining over the years.
BMC MEDICAL RESEARCH METHODOLOGY
(2022)
Article
Computer Science, Information Systems
Fanny Sampurno, Christoph Kowalski, Sarah E. Connor, Anissa Nguyen, Angels Pont Acuna, Chi-Fai Ng, Claire Foster, Gunter Feick, Olatz Garin Boronat, Sebastian Dieng, Silvana Brglevska, Stephanie Ferrante, Steven Leung, Paul Villanti, Caroline M. Moore, Ian D. Graham, Jeremy L. Millar, Mark S. Litwin, Nathan Papa
Summary: The TrueNTH Global Registry (TNGR) aims to improve patient outcomes for localized prostate cancer by collating data from healthcare institutions across multiple countries. A systematic evaluation of supporting documents and consultations with local institutions resulted in four areas of improvement.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2022)
Article
Health Care Sciences & Services
Eloise Radcliffe, Aysha Khan, David Wright, Richard Berman, Sara Demain, Claire Foster, Susan Restorick-Banks, Alison Richardson, Richard Wagland, Lynn Calman
Summary: The COVID-19 pandemic has intensified uncertainty and anxiety for people living with treatable but not curable cancer, leading to emotional impact due to lack of face-to-face contact and increased responsibilities for carers. The study highlights the challenges and lost opportunities faced by patients and carers, with implications for those living with other life-limiting conditions.
PALLIATIVE MEDICINE
(2022)
Article
Oncology
Lucy King, Sara Matthews, Claire Foster, Rachel Starkings, Patricia Holch, Kate Absolom, Stephanie Archer
Summary: This article explores the experiences of UK postgraduate research students during COVID-19. Through an online survey and qualitative data analysis, it was found that COVID-19 provided opportunities for students to develop online skills, resilience, and adaptability. However, students also faced practical difficulties, social isolation, unhealthy work/life balance, and concerns about future careers. To safeguard the future of postgraduate research students, BPOS and relevant institutions need to continue providing adequate support and development opportunities.
Article
Oncology
Bernd Kasper, Kathrin Schuster, Roger Wilson, Sorrel Bickley, Jean-Yves Blay, Denise Reinke, Markus Wartenberg, Rick Haas
Summary: This article discusses the joint efforts of Sarcoma Patients EuroNet (SPAEN) and Connective Tissue Oncology Society (CTOS) in addressing the gaps and challenges in global sarcoma care and management. The resulting position paper highlights the main findings and suggests possible future steps.
Article
Multidisciplinary Sciences
Ivaylo Vassilev, Sharon Xiaowen Lin, Lynn Calman, Josh Turner, Jane Frankland, David Wright, Claire Foster
Summary: It is important to understand the factors and processes that enable and sustain social network support for breast cancer survivors. This study found that friends and close family members provided the highest level of support, and women without higher education who did not have a partner were overall least well supported.
Article
Clinical Neurology
S. Wheelwright, R. Maunsell, S. Taylor, N. Drinkwater, C. Erridge, C. Foster, M. Hardcastle, A. Hogden, I. Lawson, D. Lisiecka, C. Mcdermott, K. E. Morrison, C. Muir, A. Recio-Saucedo, S. White
Summary: A web-based patient decision aid (PDA) was developed and tested to support people with motor neurone disease (plwMND) considering gastrostomy tube placement. The PDA went through iterative improvement based on user feedback and evaluation by plwMND and healthcare professionals (HCPs). The results showed that the PDA was well-received by users and considered valuable for the decision-making process.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
(2023)
Article
Social Sciences, Interdisciplinary
Kate Morton, Lynn Calman, Chloe Grimmett, David Wright, Helen White, Julie Young, Eloise Radcliffe, Claire Foster
Summary: The Centre for Psychosocial Research in Cancer conducts research and service evaluations to support cancer patients' well-being and quality of life. This paper reflects on how they adapted their research management and methods during the COVID-19 pandemic, and the implications for ongoing research practice. Four case studies are used to consider the benefits and challenges of adapting to remote approaches to research and evaluation delivery.
INTERNATIONAL JOURNAL OF SOCIAL RESEARCH METHODOLOGY
(2023)
Article
Gastroenterology & Hepatology
Dimitrios A. Koutoukidis, Susan A. Jebb, Claire Foster, Pete Wheatstone, Alison Horne, T. Martyn Hill, Amy Taylor, Alba Realpe, Felix Achana, Simon J. A. Buczacki
Summary: The aim of this trial is to assess the feasibility of intentional weight loss before colorectal cancer surgery and determine whether to proceed with a definitive trial.
COLORECTAL DISEASE
(2023)
Article
Health Care Sciences & Services
Kelly Kohut, Kate Morton, Karen Hurley, Lesley Turner, Caroline Dale, Susan Eastbrook, Rochelle Gold, Kate Henwood, Sonia Patton, Reshma Punjabi, Helen White, Charlene Young, Julie Young, Elizabeth Bancroft, Lily Barnett, Sarah Cable, Gaya Connolly, Beth Coad, Andrea Forman, Helen Hanson, Grace Kavanaugh, Katherine Sahan, Katie Snape, Bethany Torr, Rosalind Way, Elizabeth Winchester, Alice Youngs, Diana Eccles, Claire Foster
Summary: This study involved a workshop to co-design a patient decision aid (PtDA) with the target users, discussing the theoretical underpinning and logic model. The results highlighted the personal nature of decision-making and the importance of tailoring PtDA to individual needs. The study emphasized the need for an inductive, flexible framework approach to program theory. Patient involvement was crucial for meaningful co-design of PtDA.
HEALTH EXPECTATIONS
(2023)
Article
Oncology
Jazzine Smith, Rosie Essery, Lucy Yardley, Alison Richardson, Joanna Slodkowska-Barabasz, Cassandra Chavlet, Claire Foster, Eila Watson, Chloe Grimmett, Adam W. A. Geraghty, Paul Little, Geoffrey Sharman, Tamsin Burford, Roger Bacon, Lesley Turner, Katherine Bradbury
Summary: This study investigated the experiences of cancer survivors using the digital intervention Renewed. It found that even with limited use, Renewed can support healthy behavior changes among cancer survivors. Interventions targeting individuals who lack social support may be beneficial.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Oncology
Chloe Grimmett, Teresa Corbett, Katherine Bradbury, Kate Morton, Carl R. May, Bernardine M. Pinto, Claire Foster
Summary: This paper presents a conceptual framework for the maintenance of physical activity (PA) and its application to future interventions. The framework was developed based on systematic literature reviews and qualitative interviews with cancer patients. It includes determinants of long-term PA that are linked to behavior change techniques (BCTs) and proposed mechanisms of action (MoA).
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Public, Environmental & Occupational Health
Linda Serwaa Agyemang, Richard Wagland, Claire Foster, Chris McLean, Deborah Fenlon
Summary: This study aimed to explore the factors contributing to breast cancer disclosure among Ghanaian women. The findings revealed that women in Ghana were hesitant to disclose their diagnosis due to stigma and fears. However, they still chose to disclose to close relatives and friends for emotional and financial support.
Review
Health Care Sciences & Services
Kelly Kohut, Kate Morton, Lesley Turner, Jonathan Shepherd, Vicky Fenerty, Lois Woods, Chloe Grimmett, Diana M. Eccles, Claire Foster
Summary: This review aimed to explore the experience of patients using decision support resources in the context of genetic cancer susceptibility and the impact on decision-making outcomes. The study found that patients were satisfied with the various modes of resource delivery and personal tailoring. The impact on cognitive, emotional, and behavioural outcomes varied, but was mainly positive, suggesting the potential usefulness of these resources.
FRONTIERS IN HEALTH SERVICES
(2023)
Article
Health Care Sciences & Services
Kate Morton, Kelly Kohut, Lesley Turner, Sian J. Smith, Emma Crosbie, Neil Ryan, Chloe M. Grimmett, Diana Eccles, Claire Foster
Summary: This article presents a decision aid template for individuals with a genetic predisposition to cancer, developed through a co-design process. The template includes five core components and can be adapted for different predispositions. It aims to support informed decision-making and facilitate discussion with clinicians.
FRONTIERS IN DIGITAL HEALTH
(2022)
Article
Health Care Sciences & Services
David O'Connor, Jane Frankland, Jo Watts, Hazel Brodie, Kevin Hamer, Claire Foster, Alison Richardson
Summary: A patient portal developed for remote monitoring and supported self-management follow-up care for men with prostate cancer was found to be acceptable and easy to use by a large proportion of participants. Non-use of the portal was mainly due to lack of access to computing facilities and computer skills. Older individuals were less likely to register to use the portal.
FRONTIERS IN DIGITAL HEALTH
(2022)
Article
Health Care Sciences & Services
Louise Annemoon Jonker, Madelon T. Heijltjes, Judith A. C. Rietjens, Agnes van der Heide, Geeske Hendriksen, Johannes J. M. van Delden, Ghislaine J. M. W. van Thiel
Summary: This study explores the perceptions and experiences of patients and relatives regarding Continuous Deep Sedation (CDS). The findings suggest that patients and relatives consider CDS as a regular palliative care option and prioritize avoiding suffering at the end of life. They also claim a substantial say in the decision-making process.
HEALTH EXPECTATIONS
(2024)