Inhibitors - cellular aspects and novel approaches for tolerance

Progress toward inducing immunologic tolerance to factor VIII

(2013) D. W. Scott et al.   BLOOD

Development and Maintenance of Regulatory T cells

(2013) Naganari Ohkura et al.   IMMUNITY

Regulatory T cell epitopes (Tregitopes) in IgG induce tolerance in vivo and lack immunogenicity per se

(2013) Yan Su et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Erratum to: Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine

(2013) Margaret E McCoy et al.   MALARIA JOURNAL

Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes

(2013) Leslie P. Cousens et al.   Journal of Diabetes Research

Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells

(2012) Kwang-Chul Kwon et al.   ADVANCED DRUG DELIVERY REVIEWS

Tregitope update: Mechanism of action parallels IVIg

(2012) Leslie P. Cousens et al.   AUTOIMMUNITY REVIEWS

The gene therapy journey for hemophilia: are we there yet?

(2012) K. A. High   BLOOD

Haematopoietic stem cell transplantation for SCID patients: where do we stand?

(2012) Marina Cavazzana-Calvo et al.   BRITISH JOURNAL OF HAEMATOLOGY

Recent Progress in Gene Therapy for Hemophilia

(2012) Marinee K. Chuah et al.   HUMAN GENE THERAPY

In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity

(2012) Leslie P. Cousens et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

(2012) Daniel R Getts et al.   NATURE BIOTECHNOLOGY

Gene therapy for haemophilia: prospects and challenges to prevent or reverse inhibitor formation

(2011) David W. Scott et al.   BRITISH JOURNAL OF HAEMATOLOGY

Clinical Progress in Gene Therapy: Sustained Partial Correction of the Bleeding Disorder in Patients Suffering from Severe Hemophilia B

(2011) T. VandenDriessche et al.   HUMAN GENE THERAPY

Oral tolerance

(2011) Howard L. Weiner et al.   IMMUNOLOGICAL REVIEWS

Gene therapy for haemophilia: a long and winding road

(2011) K. A. HIGH   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

T-cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site

(2011) E. A. JAMES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

In Vivo Expansion of Regulatory T cells With IL-2/IL-2 mAb Complexes Prevents Anti-factor VIII Immune Responses in Hemophilia A Mice Treated With Factor VIII Plasmid-mediated Gene Therapy

(2011) Chao-Lien Liu et al.   MOLECULAR THERAPY

Long-term Safety and Efficacy Following Systemic Administration of a Self-complementary AAV Vector Encoding Human FIX Pseudotyped With Serotype 5 and 8 Capsid Proteins

(2011) Amit C Nathwani et al.   MOLECULAR THERAPY

A MicroRNA-regulated and GP64-pseudotyped Lentiviral Vector Mediates Stable Expression of FVIII in a Murine Model of Hemophilia A

(2011) Hideto Matsui et al.   MOLECULAR THERAPY

HLA-DR-restricted T-cell responses to factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P

(2010) R. A. ETTINGER et al.   HAEMOPHILIA

Gene Therapy with IgG-HY Fusion Proteins to Reduce Male-Specific T-Cell Reactivity In Vitro

(2010) Miranda P. Dierselhuis et al.   HUMAN GENE THERAPY

B-Cell-Delivered Gene Therapy Induces Functional T Regulatory Cells and Leads to a Loss of Antigen-Specific Effector Cells

(2010) Jonathan Skupsky et al.   MOLECULAR THERAPY

Immunomodulation for inhibitors in hemophilia A: the important role of Treg cells

(2010) Carol H Miao   Expert Review of Hematology

Anti-CD3 antibodies modulate anti-factor VIII immune responses in hemophilia A mice after factor VIII plasmid-mediated gene therapy

(2009) B. Peng et al.   BLOOD

In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance

(2009) A. Annoni et al.   BLOOD

Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"

(2008) A. S. De Groot et al.   BLOOD

Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency—lessons learned from monogenic disorders in mice and men

(2008) Lisa S Westerberg et al.   CURRENT OPINION IN IMMUNOLOGY