Thaumatococcus daniellii Seed Improves Lipid Profile in Male Wistar Rats

Authors

Franklyn Iheagwam¹ , Shalom Chinedu¹ , Opeyemi Emiloju¹ , Chisom Anichebem¹ , Ositadinma Okolie¹

1. Covenant University

Conference / event

Experimental Biology, April 2017 (Chicago, IL, United States)

Poster summary

The effect of Thaumatococcus daniellii seed ethanol extract on lipid profile in male Wistar rats was assessed using standard methods. The extract decreased cholesterol, triglyceride, low-density cholesterol and increased high-density cholesterolin in the brain, heart, testes and plasma of the experimental animals. Hence Thaumatococcus daniellii seed may be further exploited for its hypolipidemic properties in management and treatment of diseases associated with obesity.

Keywords

Thaumatococcus daniellii, Oxidative stress, Superoxide dismutase

Research areas

Agriculture, Pharmacy and Pharmacology, Biochemistry, Toxicology, Biological Sciences

References

1. Ekpo, I.A., Agbor, R.B., Okpako, E.C., Osuagwu, A. N., Ekanem, B.E. and Otu, P.A. (2012). Effect of crude oil and simulated acid rain on the growth and physiology of Thaumatococcus daniellii. Journal of Biodiversity and Environmental Sciences 2(9): 21-25.
2. Onwueme, I.C., Onochie, B.E. and Safowora, E.A. (1979). Cultivation of Thaumatococcus daniellii - the sweetener. World Crops 31: 321-325.
3. Pourghassem-Gargari, B., Ebrahimzadeh-Attary, V., Rafraf, M. and Gorbani, A. (2009). Effect of dietary supplementation with Nigella sativa L. on serum lipid profile, lipid peroxidation and antioxidant defense system in hyperlipidemic rabbits. Journal of Medicinal Plants Research 3(10): 815-821.
4. Rajib, D.N., Sohel, R., Areeful, H., Pobittro, S., Elias, M. and Mrityunjoy, B. (2015). Extraction of Borassus flabilifer root and biochemical effects on experimental mouse model lipid profile. American Journal of Life Sciences 3(1): 6-10
5. Roy, P., Thahimon, P.A, Carla, B., Nath, M.R. and Priyamol, M.V. (2014). Antihyperlipidemic activity of hydroalcoholic extract of Lawsonia inermis L. root in triton WR-1339 induced hyperlipidemic rat. World Journal of Pharmacy and Pharmaceutical Sciences 4(1):1359-1368.

Funding

No data provided

Supplemental files

No data provided

Additional information

Competing interests

None declared.

Data availability statement

Data sharing not applicable to this poster as no datasets were generated or analyzed during the current study.

Creative Commons license

Copyright © 2022 Iheagwam et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.