Advancements and issues in Preclinical Oncology

Category: Research Topics

Keywords: Preclinical , Oncology , Ethical , Issues , Advancements , Latest

Description: This space is to discuss advancements and issues in preclinical oncology including but not limited to topics such as transgenic mouse models, Humanized mice, Graft vs Host Disease, and ethical concerns.

Pinned Content Last updated 3 years ago

Came across this article in Nature a while back "Squeaky clean mice could be ruining research".
It emphasizes the importance of real-world elements in in-vivo research and how the pristine lab mice are perhaps not the best models for human disease.

Links: https://www.nature.com/articles/d41586-018-03916-9

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Humanized mice

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Humanizing mouse genome. Any thoughts regarding graft vs host disease.

Links: https://www.nature.com/articles/s41467-019-09716-7

Archived Board	Archived Date	Discussions
Humanized mice		1

3 members: Owner

Harwinder

Patrick

Wai

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