Malonic aciduria

Grant Name
Malonic aciduria
Funder
National Organization for Rare Disorders
Country or Region
United States
Research Field
Medicine, Neurology (clinical)
Biochemistry, Genetics and Molecular Biology, Molecular Medicine
Grant Size
Up to 50,000 USD
Contact Info
research@rarediseases.org
Eligibility
Mid-Career and Experienced Researchers
Description
NORD, with funding from The Hope Fund, is accepting applications for a total of $50,000, for scientific and/or clinical research studies related to malonyl-CoA decarboxylase deficiency, a rare metabolic condition that prevents the body from converting certain fats to energy. The signs and symptoms of this disorder are variable, but may include delayed development in childhood, hypotonia, seizures, diarrhea, vomiting, metabolic acidosis, hypoglycemia, ketosis, abnormal urinary compounds, lactic academia and hypertrophic cardiomyopathy. This condition is caused by mutations in the malonyl-CoA decarboxylase gene (MLYCD) gene, and is inherited as an autosomal recessive trait. The MCD enzyme is involved in the degradation of malonyl-CoA and it appears that inhibition of fatty acid synthesis as a result of malonyl-CoA accumulation is responsible for at least some of the clinical manifestations of the disorder. This condition is known as malonic aciduria, malonic acidemia, malonyl-coenzyme A decarboxylase deficiency, and MCD deficiency.

Funding resources

Purdue Grant Writing Lab: Introduction to Grant Writing Open Link
University of Wisconsin Writing Center: Planning and Writing a Grant Proposal Open Link

Quick share


Add deadline to calendar

Unable to add to calendar. No application deadline.

Have a funding opportunity that you want to list here?

Submit the grant details to support@peeref.com for review and listing.


Find Funding. Review Successful Grants.

Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.

Explore

Add your recorded webinar

Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.

Upload Now