Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products
出版年份 2013 全文链接
标题
Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products
作者
关键词
-
出版物
FREE RADICAL RESEARCH
Volume 47, Issue sup1, Pages 93-137
出版商
Informa UK Limited
发表日期
2013-04-08
DOI
10.3109/10715762.2013.792926
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Lipoic acid – biological activity and therapeutic potential
- (2014) Anna Gorąca et al. Pharmacological Reports
- Vitamin A (retinol) downregulates the receptor for advanced glycation endproducts (RAGE) by oxidant-dependent activation of p38 MAPK and NF-kB in human lung cancer A549 cells
- (2013) Matheus Augusto de Bittencourt Pasquali et al. CELLULAR SIGNALLING
- Embryonic Overexpression of Receptors for Advanced Glycation End-Products by Alveolar Epithelium Induces an Imbalance between Proliferation and Apoptosis
- (2012) Jeffrey A. Stogsdill et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Transforming dietary peptides in promising lead compounds: the case of bioavailable carnosine analogs
- (2012) Giulio Vistoli et al. AMINO ACIDS
- Redox Control of 20S Proteasome Gating
- (2012) Gustavo M. Silva et al. ANTIOXIDANTS & REDOX SIGNALING
- Attenuation of aortic injury by ursolic acid through RAGE-Nox-NFκB pathway in streptozocin-induced diabetic rats
- (2012) Min Xiang et al. ARCHIVES OF PHARMACAL RESEARCH
- Pioglitazone attenuates progression of aortic valve calcification via down-regulating receptor for advanced glycation end products
- (2012) Fei Li et al. BASIC RESEARCH IN CARDIOLOGY
- Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1
- (2012) Stefanie Grimm et al. BIOCHEMICAL JOURNAL
- Carnosine: New concept for the function of an old molecule
- (2012) A. A. Boldyrev BIOCHEMISTRY-MOSCOW
- RAGE in tissue homeostasis, repair and regeneration
- (2012) Guglielmo Sorci et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Screening System of Blocking Agents of the Receptor for Advanced Glycation Endproducts in Cells Using Fluorescence
- (2012) Dong Ho Jung et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Selenium Downregulates RAGE and NFκB Expression in Diabetic Rats
- (2012) Sneha S. Pillai et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis
- (2012) Rui Liu et al. BMC Medicine
- D-carnosine octylester attenuates atherosclerosis and renal disease in ApoE null mice fed a Western diet through reduction of carbonyl stress and inflammation
- (2012) Stefano Menini et al. BRITISH JOURNAL OF PHARMACOLOGY
- Flavour chemistry of methylglyoxal and glyoxal
- (2012) Yu Wang et al. CHEMICAL SOCIETY REVIEWS
- Formin mDia1 Mediates Vascular Remodeling via Integration of Oxidative and Signal Transduction Pathways
- (2012) Fatouma Touré et al. CIRCULATION RESEARCH
- S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis
- (2012) T. Arumugam et al. CLINICAL CANCER RESEARCH
- Specific Noncovalent Interactions at Protein-Ligand Interface: Implications for Rational Drug Design
- (2012) P. Zhou et al. CURRENT MEDICINAL CHEMISTRY
- Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications
- (2012) R. Nagai et al. DIABETES
- The Effects of Long-Term Oral Benfotiamine Supplementation on Peripheral Nerve Function and Inflammatory Markers in Patients With Type 1 Diabetes: A 24-month, double-blind, randomized, placebo-controlled trial
- (2012) D. A. Fraser et al. DIABETES CARE
- Topical treatment with anti-oxidants and Au nanoparticles promote healing of diabetic wound through receptor for advance glycation end-products
- (2012) Siang-An Chen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Alpha lipoic acid protects heart against myocardial ischemia–reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation
- (2012) Lan He et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Carbonylation of the cytoskeletal protein actin leads to aggregate formation
- (2012) Jose Pedro Castro et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cathepsins D and L reduce the toxicity of advanced glycation end products
- (2012) Stefanie Grimm et al. FREE RADICAL BIOLOGY AND MEDICINE
- Metformin Inhibits Advanced Glycation End Products (AGEs)-induced Renal Tubular Cell Injury by Suppressing Reactive Oxygen Species Generation via Reducing Receptor for AGEs (RAGE) Expression
- (2012) Y. Ishibashi et al. HORMONE AND METABOLIC RESEARCH
- Rehmannia glutinosa Suppresses Inflammatory Responses Elicited by Advanced Glycation End Products
- (2012) Gui-Hyun Baek et al. INFLAMMATION
- Trapping of Methylglyoxal by Curcumin in Cell-Free Systems and in Human Umbilical Vein Endothelial Cells
- (2012) Te-Yu Hu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Receptor for Advanced Glycation End Products (RAGE) Functions as Receptor for Specific Sulfated Glycosaminoglycans, and Anti-RAGE Antibody or Sulfated Glycosaminoglycans Deliveredin VivoInhibit Pulmonary Metastasis of Tumor Cells
- (2012) Shuji Mizumoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Chih-Yu Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2012) Vivek Rai et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2012) Young Taek Han et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2012) Lai Qian et al. JOURNAL OF NEUROLOGY
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- (2012) Wei Wei et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
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- (2012) Marcus Baumann Journal of the American Society of Hypertension
- Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level
- (2012) Yuji Ishibashi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
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- (2012) Sandra Müller-Krebs et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
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- (2012) Taehan Kim et al. REJUVENATION RESEARCH
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- (2012) Ravichandran Ramasamy et al. VASCULAR PHARMACOLOGY
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- (2012) Fang Chen et al. Asian Pacific Journal of Tropical Medicine
- Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics)
- (2011) Tomoaki Uchiki et al. AGING CELL
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- (2011) Francesco Bellia et al. AMINO ACIDS
- Enzymatic deglycation of Amadori products in bacteria: mechanisms, occurrence and physiological functions
- (2011) Veronika Maria Deppe et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
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- (2011) Sae Jeong Yang et al. ATHEROSCLEROSIS
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- (2011) M.K. Song et al. BIOCHEMICAL PHARMACOLOGY
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- (2011) Emilia Gospodarska et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Synthesis and proteasome inhibition of lithocholic acid derivatives
- (2011) Zhao Dang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The role of the proteasome in the generation of MHC class I ligands and immune responses
- (2011) E. J. A. M. Sijts et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Genistein Inhibits Advanced Glycation End Product Formation by Trapping Methylglyoxal
- (2011) Lishuang Lv et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Application of the Hard and Soft, Acids and Bases (HSAB) Theory to Toxicant–Target Interactions
- (2011) Richard M. LoPachin et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Aldose reductase (AKR1B3) regulates the accumulation of advanced glycosylation end products (AGEs) and the expression of AGE receptor (RAGE)
- (2011) Shahid P. Baba et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Human aldo–keto reductases 1B1 and 1B10: A comparative study on their enzyme activity toward electrophilic carbonyl compounds
- (2011) Yi Shen et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Phenol Group in Pyridoxamine Acts as a Stabilizing Element for Its Carbinolamines and Schiff Bases
- (2011) Catalina Caldés et al. CHEMISTRY & BIODIVERSITY
- Design, Synthesis, ADME Properties, and Pharmacological Activities of β-Alanyl-D-histidine (D-Carnosine) Prodrugs with Improved Bioavailability
- (2011) Marica Orioli et al. ChemMedChem
- RAGE biology, atherosclerosis and diabetes
- (2011) Drazenka Pongrac Barlovic et al. CLINICAL SCIENCE
- Interactions of glutathione transferases with 4-hydroxynonenal
- (2011) Larissa M. Balogh et al. DRUG METABOLISM REVIEWS
- Glutathione transferases: a structural perspective
- (2011) Aaron Oakley DRUG METABOLISM REVIEWS
- Therapeutic Potential of Copper Chelation with Triethylenetetramine in Managing Diabetes Mellitus and Alzheimerʼs Disease
- (2011) Garth J.S. Cooper DRUGS
- Involvement of RAGE, MAPK and NF-κB pathways in AGEs-induced MMP-9 activation in HaCaT keratinocytes
- (2011) Ping Zhu et al. EXPERIMENTAL DERMATOLOGY
- Dual localization of glutathione S-transferase in the cytosol and mitochondria: implications in oxidative stress, toxicity and disease
- (2011) Haider Raza FEBS Journal
- Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages
- (2011) Mohammad Shoeb et al. FREE RADICAL BIOLOGY AND MEDICINE
- Immune and non-immune functions of the immunoproteasome
- (2011) Arkhjamil Angeles Frontiers in Bioscience-Landmark
- Resorcylidene Aminoguanidine (RAG) Improves Cardiac Mitochondrial Bioenergetics Impaired by Hyperglycaemia in a Model of Experimental Diabetes
- (2011) Magdalena Labieniec-Watala et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hibiscus sabdariffaPolyphenolic Extract Inhibits Hyperglycemia, Hyperlipidemia, and Glycation-Oxidative Stress while Improving Insulin Resistance
- (2011) Chiung-Huei Peng et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Competitive binding between 4,4′-diphenylmethane-bis(methyl) carbamate and RAGE ligand MG-H1 on human umbilical vein endothelial cell by cell membrane chromatography
- (2011) Liang Feng et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- The protective effect of Salvia miltiorrhiza in an animal model of early experimentally induced diabetic nephropathy
- (2011) Sang-Hun Lee et al. JOURNAL OF ETHNOPHARMACOLOGY
- Efficiency of Trapping Methylglyoxal by Phenols and Phenolic Acids
- (2011) Chih-Yu Lo et al. JOURNAL OF FOOD SCIENCE
- Cross-Linking Mechanisms of Arginine and Lysine with α,β-Dicarbonyl Compounds in Aqueous Solution
- (2011) Rasoul Nasiri et al. JOURNAL OF PHYSICAL CHEMISTRY A
- On the Outstanding Antioxidant Capacity of Edaravone Derivatives through Single Electron Transfer Reactions
- (2011) Adriana Pérez-González et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Role of High Mobility Group Box 1 (HMGB1) in Wound Healing
- (2011) Qiang Zhang et al. JOURNAL OF SURGICAL RESEARCH
- What is the role of the receptor for advanced glycation end products-ligand axis in liver injury?
- (2011) Giuseppina Basta et al. LIVER TRANSPLANTATION
- Advanced glycation end products enhance reactive oxygen and nitrogen species generation in neutrophils in vitro
- (2011) Savita Bansal et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- The design and delivery of a thermally responsive peptide to inhibit S100B-mediated neurodegeneration
- (2011) S.M. Hearst et al. NEUROSCIENCE
- Inverse Association of Vitamin C with Cataract in Older People in India
- (2011) Ravilla D. Ravindran et al. OPHTHALMOLOGY
- Beneficial effects of metformin and irbesartan on advanced glycation end products (AGEs)–RAGE-induced proximal tubular cell injury
- (2011) Yuji Ishibashi et al. PHARMACOLOGICAL RESEARCH
- TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding
- (2011) Masakiyo Sakaguchi et al. PLoS One
- Eye Lens in Aging and Diabetes: Effect of Quercetin
- (2011) Milan Stefek et al. REJUVENATION RESEARCH
- Glyoxalase in ageing
- (2011) Mingzhan Xue et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- A Monoclonal Antibody Against RAGE Alters Gene Expression and is Protective in Experimental Models of Sepsis and Pneumococcal Pneumonia
- (2011) Eirini Christaki et al. SHOCK
- Advanced Glycation End Product Recognition by the Receptor for AGEs
- (2011) Jing Xue et al. STRUCTURE
- RAGE: a single receptor fits multiple ligands
- (2011) Günter Fritz TRENDS IN BIOCHEMICAL SCIENCES
- NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease
- (2011) A. Boutten et al. TRENDS IN MOLECULAR MEDICINE
- Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae
- (2011) Undine Kruegel et al. PLoS Genetics
- Pentoxifylline alleviates high-fat diet-induced non-alcoholic steatohepatitis and early atherosclerosis in rats by inhibiting AGE and RAGE expression
- (2010) Jing Wu et al. ACTA PHARMACOLOGICA SINICA
- Kaempferol modulates pro-inflammatory NF-κB activation by suppressing advanced glycation endproducts-induced NADPH oxidase
- (2010) Ji Min Kim et al. AGE
- Aldose Reductase and AGE-RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats
- (2010) Kellie McCormick Hallam et al. AGING CELL
- PF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease
- (2010) Marwan N. Sabbagh et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands
- (2010) Narayanam V. Rao et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Oxidative protein damage and the proteasome
- (2010) S. Grimm et al. AMINO ACIDS
- Glycation research in amino acids: a place to call home
- (2010) Naila Rabbani et al. AMINO ACIDS
- Enzymatic repair of Amadori products
- (2010) Emile Van Schaftingen et al. AMINO ACIDS
- Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics
- (2010) Casper G. Schalkwijk et al. AMINO ACIDS
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- (2010) Benaissa Bouguerne et al. ANTIOXIDANTS & REDOX SIGNALING
- Citric acid inhibits development of cataracts, proteinuria and ketosis in streptozotocin (type 1) diabetic rats
- (2010) Ryoji Nagai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nifedipine inhibits advanced glycation end products (AGEs) and their receptor (RAGE) interaction-mediated proximal tubular cell injury via peroxisome proliferator-activated receptor-gamma activation
- (2010) Takanori Matsui et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes
- (2010) Andrew M. Pickering et al. BIOCHEMICAL JOURNAL
- Substrate Specificity Combined with Stereopromiscuity in Glutathione Transferase A4-4-Dependent Metabolism of 4-Hydroxynonenal
- (2010) Larissa M. Balogh et al. BIOCHEMISTRY
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- (2010) Mukesh Maheshwari et al. BIOCHEMISTRY
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- (2010) Fatemeh Moheimani et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2010) Kirtan V. Tarwadi et al. BIOLOGICAL TRACE ELEMENT RESEARCH
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- (2010) Ulrike Seifert et al. CELL
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- (2010) J. Lu et al. CEREBRAL CORTEX
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- (2010) Nicholas G. Kesinger et al. CHEMICAL RESEARCH IN TOXICOLOGY
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- (2010) Niccolo Lanati et al. Current Vascular Pharmacology
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- (2010) A. Alkhalaf et al. DIABETES CARE
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- (2010) Yasuaki Hayashino et al. DIABETES RESEARCH AND CLINICAL PRACTICE
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- (2010) Yu-Hong Jing et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
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- (2010) J. Lu et al. DIABETOLOGIA
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- (2010) Asaad A. Ghanem et al. EUROPEAN JOURNAL OF OPHTHALMOLOGY
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- (2010) Martina Krautwald et al. EXPERIMENTAL GERONTOLOGY
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- (2010) Linshan Shang et al. PLoS One
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- (2010) Yuhki Sakuraoka WORLD JOURNAL OF GASTROENTEROLOGY
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- (2009) Yogendra S. Rajawat et al. AGEING RESEARCH REVIEWS
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- (2009) S. M. A. Pascal et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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- (2009) Giancarlo Aldini et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2009) M. Kumano-Kuramochi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2009) Yuji Ishibashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2009) Kate Petersen Shay et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
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- (2009) Maneesh Mailankot et al. BIOGERONTOLOGY
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- (2009) Mitsugu Fukuda et al. BIOMEDICAL RESEARCH-TOKYO
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- (2009) N. André Sasaki et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2009) Yuri NOMI et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
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- (2009) Makoto Shimizu et al. CHEMICAL COMMUNICATIONS
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- (2009) Cristobal L. Miranda et al. CHEMICAL RESEARCH IN TOXICOLOGY
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- (2009) Kumar P. Chandra et al. CLINICAL DRUG INVESTIGATION
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- (2009) S. P. Baba et al. DIABETES
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- (2009) Xueping Liu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2009) H. Stracke et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
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- (2009) John W. Baynes et al. Experimental Diabetes Research
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- (2009) Rachael A. Dunlop et al. IUBMB LIFE
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- (2009) Deepa Joshi et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
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- (2009) Toshihide Kawai et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
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- (2009) Carla Iacobini et al. JOURNAL OF PATHOLOGY
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- (2009) Sho-ichi Yamagishi et al. PHARMACOLOGICAL RESEARCH
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- (2009) Takanori Matsui et al. PHARMACOLOGICAL RESEARCH
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- (2009) Seiichi Sakatani et al. PLoS One
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- (2008) Fu-Ling Yan et al. ACTA NEUROPATHOLOGICA
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- (2008) Miquel Adrover et al. AMINO ACIDS
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- (2008) I. Nourmohammadi et al. ANNALS OF NUTRITION AND METABOLISM
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- (2008) Tobias Jung et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
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- (2008) Kerstin Pietsch et al. BIOGERONTOLOGY
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- (2008) Miquel Adrover et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2008) Miquel Adrover et al. BIOORGANIC CHEMISTRY
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- (2008) A Bhatwadekar et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Apple Polyphenols, Phloretin and Phloridzin: New Trapping Agents of Reactive Dicarbonyl Species
- (2008) Xi Shao et al. CHEMICAL RESEARCH IN TOXICOLOGY
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- (2008) Rhea Mehta et al. CHEMICO-BIOLOGICAL INTERACTIONS
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- (2008) Bernard Testa et al. CHEMISTRY & BIODIVERSITY
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- (2008) M. Cocchietto et al. DIABETES & METABOLISM
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- (2008) J. L. Figarola et al. DIABETOLOGIA
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- (2008) Yuko Hirano et al. EMBO JOURNAL
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- (2008) R. M. Liscic et al. EUROPEAN JOURNAL OF NEUROLOGY
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- (2008) L. Xu et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
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- (2008) Seetal Dodd et al. EXPERT OPINION ON BIOLOGICAL THERAPY
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- (2008) Martin D. Rees et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2008) Sylvain Galvani et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2008) Yang Zheng et al. HEMOGLOBIN
- Proteasome activation as a novel antiaging strategy
- (2008) Niki Chondrogianni et al. IUBMB LIFE
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- (2008) Larissa M. Balogh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Barry I. Hudson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Su-Yen Goh et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2008) Hyun Young KIM et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
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- (2008) Pedro Jorge Silva JOURNAL OF ORGANIC CHEMISTRY
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- (2008) Giangiacomo Beretta et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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- (2008) P. Burcham et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
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- (2008) Rina Rosenzweig et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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- (2008) Berislav V. Zlokovic Neurotherapeutics
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- (2008) A LAU et al. PHARMACOLOGICAL RESEARCH
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- (2008) D. Meredith PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
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- (2008) Young-Joon Surh et al. PLANTA MEDICA
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- (2008) Sho-ichi Yamagishi et al. PROTEIN AND PEPTIDE LETTERS
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- (2008) Jau-Shyang Huang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
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- (2007) Giuseppina Basta ATHEROSCLEROSIS
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- (2007) Andreas Kampkötter et al. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
- Olmesartan blocks advanced glycation end products (AGEs)-induced angiogenesis in vitro by suppressing receptor for AGEs (RAGE) expression
- (2007) Sho-ichi Yamagishi et al. MICROVASCULAR RESEARCH
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