期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 8, 期 4, 页码 319-330出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955708783955953
关键词
carbonyl stress; acrolein; protein adducts; hydralazine
This mini-review highlights the chemical and cytoprotective properties of various hydralazine analogues that block the induction of cell death by acrolein, a highly toxic contributor to carbonyl stress during a diverse range of human diseases. Recent work on the action of hydralazine against various carbonyl-mediated pathologies is also reviewed.
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