Pioglitazone attenuates progression of aortic valve calcification via down-regulating receptor for advanced glycation end products

S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-κB signaling

(2012) H. Christian Volz et al.   BASIC RESEARCH IN CARDIOLOGY

Thiazolidinediones and Risk of Heart Failure in Patients with or at High Risk of Type 2 Diabetes Mellitus

(2011) Adrian V. Hernandez et al.   American Journal of Cardiovascular Drugs

Pioglitazone limits myocardial infarct size, activates Akt, and upregulates cPLA2 and COX-2 in a PPAR-γ-independent manner

(2011) Yochai Birnbaum et al.   BASIC RESEARCH IN CARDIOLOGY

The potential effects of anti-diabetic medications on myocardial ischemia–reperfusion injury

(2011) Yumei Ye et al.   BASIC RESEARCH IN CARDIOLOGY

Double-blind, randomized, multicentre, and active comparator controlled investigation of the effect of Pioglitazone, Metformin, and the combination of both on cardiovascular risk in patients with type 2 diabetes receiving stable basal insulin therapy: the PIOCOMB study

(2011) Markolf Hanefeld et al.   Cardiovascular Diabetology

Calcific Aortic Valve Disease: Not Simply a Degenerative Process

(2011) Nalini M. Rajamannan et al.   CIRCULATION

Upregulation of the 5-Lipoxygenase Pathway in Human Aortic Valves Correlates With Severity of Stenosis and Leads to Leukotriene-Induced Effects on Valvular Myofibroblasts

(2011) Edit Nagy et al.   CIRCULATION

The Antioxidant N-Acetylcysteine Promotes Atherosclerotic Plaque Stabilization Through Suppression of RAGE, MMPs and NF-κB in ApoE-Deficient Mice

(2011) Yonggang Lu et al.   Journal of Atherosclerosis and Thrombosis

Activation of Receptor for Advanced Glycation End Products Induces Osteogenic Differentiation of Vascular Smooth Muscle Cells

(2011) Toshihiro Suga et al.   Journal of Atherosclerosis and Thrombosis

Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice

(2011) Eleni Maniati et al.   JOURNAL OF CLINICAL INVESTIGATION

Risk of Death and Cardiovascular Outcomes with Thiazolidinediones: A Study with the General Practice Research Database and Secondary Care Data

(2011) Arlene M. Gallagher et al.   PLoS One

Vascular Endothelial Growth Factor–Secreting Mast Cells and Myofibroblasts

(2010) Suvi Syväranta et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

S100A12 in Vascular Smooth Muscle Accelerates Vascular Calcification in Apolipoprotein E–Null Mice by Activating an Osteogenic Gene Regulatory Program

(2010) Marion A. Hofmann Bowman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Circulating soluble receptor for advanced glycation end-product levels are decreased in patients with calcific aortic valve stenosis

(2010) Giuseppina Basta et al.   ATHEROSCLEROSIS

HMGB1: the missing link between diabetes mellitus and heart failure

(2010) H. Christian Volz et al.   BASIC RESEARCH IN CARDIOLOGY

Recombinant apolipoprotein A-I Milano rapidly reverses aortic valve stenosis and decreases leaflet inflammation in an experimental rabbit model

(2010) W. S. Speidl et al.   EUROPEAN HEART JOURNAL

Effect of insulin on the differential expression of VLDL receptor isoforms of SGC7901 cell and its biological implication

(2010) Zhejun Cai et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Tumor Necrosis Factor-  Accelerates the Calcification of Human Aortic Valve Interstitial Cells Obtained from Patients with Calcific Aortic Valve Stenosis via the BMP2-Dlx5 Pathway

(2010) Z. Yu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Arterial Calcification Is Driven by RAGE in Enpp1–/– Mice

(2010) Denise L. Cecil et al.   JOURNAL OF VASCULAR RESEARCH

Peroxisome proliferator-activated receptor-γ activation attenuates cardiac fibrosis in type 2 diabetic rats: the effect of rosiglitazone on myocardial expression of receptor for advanced glycation end products and of connective tissue growth factor

(2009) Sang-Hyun Ihm et al.   BASIC RESEARCH IN CARDIOLOGY

RAGE mediates oxidized LDL-induced pro-inflammatory effects and atherosclerosis in non-diabetic LDL receptor-deficient mice

(2009) L. Sun et al.   CARDIOVASCULAR RESEARCH

Relationship of Metabolic Syndrome With Incident Aortic Valve Calcium and Aortic Valve Calcium Progression: The Multi-Ethnic Study of Atherosclerosis (MESA)

(2009) R. Katz et al.   DIABETES

RAGE signaling in inflammation and arterial aging

(2009) Li Lin   Frontiers in Bioscience-Landmark

Advanced Glycation End Products Induce Calcification of Vascular Smooth Muscle Cells through RAGE/p38 MAPK

(2009) Takahisa Tanikawa et al.   JOURNAL OF VASCULAR RESEARCH

2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease

(2008) et al.   CIRCULATION

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes

(2008) A. Soro-Paavonen et al.   DIABETES

Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE–/– mice

(2008) Evis Harja et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxidant Generation Predominates Around Calcifying Foci and Enhances Progression of Aortic Valve Calcification

(2007) Marcel Liberman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY