Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature
出版年份 2014 全文链接
标题
Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC PATENTS
Volume 24, Issue 4, Pages 383-400
出版商
Informa Healthcare
发表日期
2014-01-17
DOI
10.1517/13543776.2014.877443
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells
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- OPB-31121, a novel small molecular inhibitor, disrupts the JAK2/STAT3 pathway and exhibits an antitumor activity in gastric cancer cells
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- Therapeutic modulators of STAT signalling for human diseases
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- Phospho-Ser727 of STAT3 regulates STAT3 activity by enhancing dephosphorylation of phospho-Tyr705 largely through TC45
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- XZH-5 Inhibits STAT3 Phosphorylation and Enhances the Cytotoxicity of Chemotherapeutic Drugs in Human Breast and Pancreatic Cancer Cells
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- First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy
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- XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells
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- STAT3 activation in monocytes accelerates liver cancer progression
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- STAT-3 Inhibitors: State of the Art and New Horizons for Cancer Treatment
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- Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3
- (2011) Fang-Ming Gu WORLD JOURNAL OF GASTROENTEROLOGY
- Identification of a Small Molecule Inhibitor of Importin β Mediated Nuclear Import by Confocal On-Bead Screening of Tagged One-Bead One-Compound Libraries
- (2010) Martin Hintersteiner et al. ACS Chemical Biology
- STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma
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- Signal transducer and activator of transcription 3 inhibitors: a patent review
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- Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein
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- Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic Acid-Based Small Molecules: Potent in vitro and Tumor Cell Activities
- (2009) Steven Fletcher et al. CHEMBIOCHEM
- Flavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism
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- Crystal structure of unphosphorylated STAT3 core fragment
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- Lack of toxicity of a STAT3 decoy oligonucleotide
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- STAT3 as a target for inducing apoptosis in solid and hematological tumors
- (2008) Khandaker Al Zaid Siddiquee et al. CELL RESEARCH
- A Novel Inhibitor of Signal Transducers And Activators Of Transcription 3 Activation Is Efficacious Against Established Central Nervous System Melanoma and Inhibits Regulatory T Cells
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- Targeting STAT3 in cancer: how successful are we?
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