Benzofuran derivatives: a patent review

Synthesis and Anti-inflammatory Activity of Some Benzofuran and Benzopyran-4-one Derivatives

(2012) Fatma Abd El-Fattah Ragab et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Synthesis of Benzofuro[3,2-e]-1,4-diazepines of Pharmacological Interest

(2012) K. M. Basavaraja et al.   E-Journal of Chemistry

3-(Substituted Aryl)-1-benzofuranyl-2-propenones: Antimicrobial Properties of Some Chalcones-Type Compounds and their 2-Pyrazoline Derivatives

(2012) Demet Coskun et al.   E-Journal of Chemistry

In vitro antiplasmodial activity of spiro benzofuran compound from mangrove plant of Southern India

(2012) Ravikumar Sundaram et al.   Asian Pacific Journal of Tropical Medicine

A new method for induced fit docking (genius) and its application to virtual screening of novel HCV NS3-4A protease inhibitors

(2011) Daisuke Takaya et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors

(2011) Yantao He et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase

(2011) Christophe Antczak et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of α,β-unsaturated lactones as potent immunosuppressive agents

(2011) Sun-Mi Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anti-cancer effects of a novel compound HS-113 on cell growth, apoptosis, and angiogenesis in human hepatocellular carcinoma cells

(2011) Myung-Joo Choi et al.   CANCER LETTERS

Synthesis and antimicrobial evaluation of new benzofuran derivatives

(2011) Xizhen Jiang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rational Design of Potent, Small, Synthetic Allosteric Inhibitors of Thrombin

(2011) Preetpal Singh Sidhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties

(2011) Bernard L. Flynn et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anti-inflammatory and Cytotoxic Neoflavonoids and Benzofurans fromPterocarpus santalinus

(2011) Shou-Fang Wu et al.   JOURNAL OF NATURAL PRODUCTS

Lignan Derivatives fromKrameria lappaceaRoots Inhibit Acute Inflammation in Vivo and Pro-inflammatory Mediators in Vitro

(2011) Lisa Baumgartner et al.   JOURNAL OF NATURAL PRODUCTS

Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus

(2011) Jeffrey A. Pfefferkorn et al.   MedChemComm

Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1

(2010) Bin Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effect of hydrogen donating ability of benzofuranone on the antioxidant activity

(2010) Xin Meng et al.   CHINESE SCIENCE BULLETIN

Preparation of new polycyclic compounds derived from benzofurans and furochromones. An approach to novel 1,2,3-thia-, and selena-diazolofurochromones of anticipated antitumor activities

(2010) Sanaa M.Sh. Atta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel antiviral benzofuran-transition metal complexes

(2010) Shadia A. Galal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and antitubercular evaluation of novel series of 3-benzofuran-5-aryl-1-pyrazolyl-pyridylmethanone and 3-benzofuran-5-aryl-1-pyrazolylcarbonyl-4-oxo-naphthyridin analogs

(2010) Kuntal Manna et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Two new benzofuran derivatives with anti-inflammatory activity from Liriope spicata var. prolifera

(2010) Zheng-Fang Hu et al.   FITOTERAPIA

New benzofuran derivatives as an antioxidant agent

(2010) SS Rindhe et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Synthesis, Crystal Structures, Insecticidal Activities, and Structure−Activity Relationships of NovelN′-tert-Butyl-N′-substituted-benzoyl-N-[di(octa)hydro]benzofuran{(2,3-dihydro)benzo[1,3]([1,4])dioxine}carbohydrazide Derivatives

(2010) Zhiqiang Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Novel Derivative of Benzofuran Induces Cell Death Mostly by G2/M Cell Cycle Arrest through p53-dependent Pathway but Partially by Inhibition of NF-κB

(2010) Sunil K. Manna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The hypolipidemic activity of novel benzofuran-2-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats: a comparison with bezafibrate

(2010) Ghassan Shattat et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

AMP-Activated Protein Kinase (AMPK) Activation by Benzofurans and Coumestans Isolated fromErythrina abyssinica

(2010) Phi-Hung Nguyen et al.   JOURNAL OF NATURAL PRODUCTS

Potent in vitro and in vivo antitubercular activity of certain newly synthesized indophenazine 1,3,5-trisubstituted pyrazoline derivatives bearing benzofuran

(2010) Kuntal Manna et al.   MEDICINAL CHEMISTRY RESEARCH

Correlation between Cytotoxic Activities and Reduction Potentials of Heterocyclic Quinones

(2010) Junko Koyama et al.   MOLECULES

Comparison of HCV NS3 protease and NS5B polymerase inhibitor activity in 1a, 1b and 2a replicons and 2a infectious virus

(2009) Matthew S. Paulson et al.   ANTIVIRAL RESEARCH

First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor Xa

(2009) Jenson Verghese et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Microwave assisted synthesis of new indophenazine 1,3,5-trisubstruted pyrazoline derivatives of benzofuran and their antimicrobial activity

(2009) Kuntal Manna et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and structure–activity relationships of novel benzofuran farnesyltransferase inhibitors

(2009) Kohsuke Asoh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of potent antitumor and antiviral benzofuran derivatives

(2009) Shadia A. Galal et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Convenient synthesis and antimicrobial evaluation of some novel 2-substituted-3-methylbenzofuran derivatives

(2009) Hatem A. Abdel-Aziz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Stereoselective synthesis and antimicrobial activity of benzofuran-based (1E)-1-(piperidin-1-yl)-N2-arylamidrazones

(2009) Hatem A. Abdel-Aziz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation ofin vitroantiviral activity of 2-[3-(substituted phenyl)-4,5-dihydro-1H-5-pyrazolyl]benzofuran-3-yl chloride derivatives

(2009) M. Shahar Yar et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis and Antiprotozoal Properties of Pentamidine Congeners Bearing the Benzofuran Motif

(2009) Stanislav A. Bakunov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antiplasmodial Activities of Homogentisic Acid Derivative Protein Kinase Inhibitors Isolated from a Vanuatu Marine Sponge Pseudoceratina sp.

(2009) Nicolas Lebouvier et al.   Marine Drugs

Synthesis and antitumor activity of some benzofuryl-substituted 1,2,4-triazoles

(2009) M. A. Kaldrikyan et al.   PHARMACEUTICAL CHEMISTRY JOURNAL

Development of Intergenotypic Chimeric Replicons To Determine the Broad-Spectrum Antiviral Activities of Hepatitis C Virus Polymerase Inhibitors

(2008) K. J. Herlihy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE): Discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1′ substituents

(2008) Zhonghui Lu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS