Genetic polymorphisms in placental transporters: implications for fetal drug exposure to oral antidiabetic agents

Role of human placental apical membrane transporters in the efflux of glyburide, rosiglitazone, and metformin

(2010) Sarah J. Hemauer et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

SLCO1B1 Polymorphism and Oral Antidiabetic Drugs

(2010) Annikka Kalliokoski et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Breast Cancer Resistance Protein (BCRP)-Mediated Glyburide Transport: Effect of the C421A/Q141K BCRP Single-Nucleotide Polymorphism

(2010) E. K. Pollex et al.   DRUG METABOLISM AND DISPOSITION

Pharmacokinetics of Metformin during Pregnancy

(2010) S. Eyal et al.   DRUG METABOLISM AND DISPOSITION

Placental P-glycoprotein and breast cancer resistance protein: Influence of polymorphisms on fetal drug exposure and physiology

(2010) J.R. Hutson et al.   PLACENTA

Opiates inhibit paclitaxel uptake by P-glycoprotein in preparations of human placental inside-out vesicles

(2009) Sarah J. Hemauer et al.   BIOCHEMICAL PHARMACOLOGY

Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms

(2009) Sarah J. Hemauer et al.   BIOCHEMICAL PHARMACOLOGY

Impact of OATP transporters on pharmacokinetics

(2009) A Kalliokoski et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin

(2009) M V Tzvetkov et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The role of organic cation transporters (OCTs) in the transfer of metformin in the dually perfused human placenta

(2009) Kristiina Tertti et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Developmental expression of drug metabolizing enzymes and transporter proteins in human placenta and fetal tissues

(2009) Päivi Myllynen et al.   Expert Opinion on Drug Metabolism & Toxicology

Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs

(2009) Ichiro Ieiri et al.   Expert Opinion on Drug Metabolism & Toxicology

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

Functional Genetic Variation in the Basal Promoter of the Organic Cation/Carnitine Transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5)

(2009) H. Tahara et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response

(2009) Edward B. Mougey et al.   Pharmacogenetics and Genomics

Impact of regulatory polymorphisms in organic anion transporter genes in the human liver

(2009) Masayo Aoki et al.   Pharmacogenetics and Genomics

Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population

(2009) Ji-Ye Yin et al.   Pharmacogenetics and Genomics

Inhibition of placental P-glycoprotein: impact on indinavir transfer to the foetus

(2008) Sreeja Sudhakaran et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Interaction of Oral Antidiabetic Drugs With Hepatic Uptake Transporters: Focus on Organic Anion Transporting Polypeptides and Organic Cation Transporter 1

(2008) I. Bachmakov et al.   DIABETES

Trends in the Prevalence of Preexisting Diabetes and Gestational Diabetes Mellitus Among a Racially/Ethnically Diverse Population of Pregnant Women, 1999-2005

(2008) J. M. Lawrence et al.   DIABETES CARE

Effect of Endotoxin on the Expression of Placental Drug Transporters and Glyburide Disposition in Pregnant Rats

(2008) V. Petrovic et al.   DRUG METABOLISM AND DISPOSITION

Influence of adenosine triphosphate and ABCB1 (MDR1) genotype on the P-glycoprotein-dependent transfer of saquinavir in the dually perfused human placenta

(2008) M Rahi et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Different Effects ofSLCO1B1Polymorphism on the Pharmacokinetics and Pharmacodynamics of Repaglinide and Nateglinide

(2008) Annikka Kalliokoski et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Effect of albumin on transplacental transfer and distribution of rosiglitazone and glyburide

(2008) Tatiana N. Nanovskaya et al.   Journal of Maternal-Fetal & Neonatal Medicine

Investigating the potential role of multi-drug resistance protein (MRP) transporters in fetal to maternal glyburide efflux in the human placenta

(2008) C. Gedeon et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Functional analysis of nonsynonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 3

(2008) Kazuhiro Kobayashi et al.   Pharmacogenetics and Genomics

The Role of Placental Breast Cancer Resistance Protein in the Efflux of Glyburide across the Human Placenta

(2008) E. Pollex et al.   PLACENTA

Carrier-mediated transport of metformin across the human placenta determined by using theex vivo perfusion of the placental cotyledon model

(2008) Michal Kovo et al.   PRENATAL DIAGNOSIS

Case series of rosiglitazone used during the first trimester of pregnancy

(2008) Ghassan F. Haddad et al.   REPRODUCTIVE TOXICOLOGY

Determination of metformin transfer across the human placenta using a dually perfused ex vivo placental cotyledon model

(2007) Michal Kovo et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Breast Cancer Resistance Protein: Mediating the Trans-placental Transfer of Glyburide across the Human Placenta

(2007) C. Gedeon et al.   PLACENTA