标题
Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer
作者
关键词
-
出版物
EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 239, Issue 11, Pages 1489-1504
出版商
SAGE Publications
发表日期
2014-06-21
DOI
10.1177/1535370214538743
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes
- (2013) Ling-Chun Kong et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Activation of the nuclear receptor FXR enhances hepatocyte chemoprotection and liver tumor chemoresistance against genotoxic compounds
- (2013) Javier Vaquero et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Burdock Fermented byAspergillus awamoriElevates CecalBifidobacterium, and Reduces Fecal Deoxycholic Acid and Adipose Tissue Weight in Rats Fed a High-Fat Diet
- (2013) Yukako OKAZAKI et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Systemic bile acid sensing by G protein-coupled bile acid receptor 1 (GPBAR1) promotes PYY and GLP-1 release
- (2013) C Ullmer et al. BRITISH JOURNAL OF PHARMACOLOGY
- Endogenously produced hydrogen sulfide supports tumor cell growth and proliferation
- (2013) Csaba Szabo et al. CELL CYCLE
- Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist
- (2013) Sama I. Sayin et al. Cell Metabolism
- Probiotics in the management of irritable bowel syndrome and inflammatory bowel disease
- (2013) Kevin Whelan et al. CURRENT OPINION IN GASTROENTEROLOGY
- Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids
- (2013) Masaaki Miyata et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Probiotics as a Novel Treatment for Non-Alcoholic Fatty Liver Disease; A Systematic Review on the Current Evidences
- (2013) Roya Kelishadi et al. Hepatitis Monthly
- The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice
- (2013) Noémie Péan et al. HEPATOLOGY
- TGR5 signalling inhibits the production of pro-inflammatory cytokines byin vitrodifferentiated inflammatory and intestinal macrophages in Crohn's disease
- (2013) Kazuaki Yoneno et al. IMMUNOLOGY
- The Bile Acid Receptor TGR5 Does Not Interact with β-Arrestins or Traffic to Endosomes but Transmits Sustained Signals from Plasma Membrane Rafts
- (2013) Dane D. Jensen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease
- (2013) Rachel H. McMahan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modulation of the fecal bile acid profile by gut microbiota in cirrhosis
- (2013) Genta Kakiyama et al. JOURNAL OF HEPATOLOGY
- Consumption of Vitamin B6 Reduces Fecal Ratio of Lithocholic Acid to Deoxycholic Acid, a Risk Factor for Colon Cancer, in Rats Fed a High-Fat Diet
- (2013) Yukako OKAZAKI et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- The solute carrier family 10 (SLC10): Beyond bile acid transport
- (2013) Tatiana Claro da Silva et al. MOLECULAR ASPECTS OF MEDICINE
- Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
- (2013) Shin Yoshimoto et al. NATURE
- Diet rapidly and reproducibly alters the human gut microbiome
- (2013) Lawrence A. David et al. NATURE
- The Bile Acid Sensor FXR Is Required for Immune-Regulatory Activities of TLR-9 in Intestinal Inflammation
- (2013) Barbara Renga et al. PLoS One
- Enhanced fasting and post-prandial plasma bile acid responses after Roux-en-Y gastric bypass surgery
- (2013) Malin Werling et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
- (2013) N. Kayagaki et al. SCIENCE
- Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice
- (2013) V. K. Ridaura et al. SCIENCE
- Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity
- (2013) A. P. Liou et al. Science Translational Medicine
- Effects of probiotics on nonalcoholic fatty liver disease: A meta-analysis
- (2013) Yan-Yan Ma WORLD JOURNAL OF GASTROENTEROLOGY
- Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity
- (2013) Fei Li et al. Nature Communications
- Fiber and Prebiotics: Mechanisms and Health Benefits
- (2013) Joanne Slavin Nutrients
- Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease
- (2012) A. Zarrinpar et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Enteropathogenic Escherichia coli inhibits ileal sodium-dependent bile acid transporter ASBT
- (2012) Fadi Annaba et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice
- (2012) Matthew J. Potthoff et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Expression of bile acid receptor TGR5 in gastric adenocarcinoma
- (2012) Weibiao Cao et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- A novel mechanism for gut barrier dysfunction by dietary fat: epithelial disruption by hydrophobic bile acids
- (2012) Lotta K. Stenman et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Bile acids: From digestion to cancers
- (2012) Marine Baptissart et al. BIOCHIMIE
- Gut microbiota-derived propionate reduces cancer cell proliferation in the liver
- (2012) L B Bindels et al. BRITISH JOURNAL OF CANCER
- Polyphenol-rich extract of pomegranate peel alleviates tissue inflammation and hypercholesterolaemia in high-fat diet-induced obese mice: potential implication of the gut microbiota
- (2012) Audrey M. Neyrinck et al. BRITISH JOURNAL OF NUTRITION
- Bile Acid Promotes Intestinal Metaplasia and Gastric Carcinogenesis
- (2012) M. Tatsugami et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances Cyclin D1 expression and promotes human endometrial cancer cell proliferation
- (2012) Ivan Casaburi et al. CELL CYCLE
- Signaling pathways bridging microbial-triggered inflammation and cancer
- (2012) Maulilio John Kipanyula et al. CELLULAR SIGNALLING
- The Role of Bile After Roux-en-Y Gastric Bypass in Promoting Weight Loss and Improving Glycaemic Control
- (2012) Dimitri J. Pournaras et al. ENDOCRINOLOGY
- Enterobacteria-mediated deconjugation of taurocholic acid enhances ileal farnesoid X receptor signaling
- (2012) Hideaki Kuribayashi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Toll-Like Receptor 2–Mediated Intestinal Injury and Enteric Tumor Necrosis Factor Receptor I Contribute to Liver Fibrosis in Mice
- (2012) Phillipp Hartmann et al. GASTROENTEROLOGY
- Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis
- (2012) Wei-Dong Chen et al. HEPATOLOGY
- Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer
- (2012) Yanjun Jiang et al. HEPATOLOGY
- Critical role of farnesoid X receptor for hepatocellular carcinoma cell proliferation
- (2012) T. Fujino et al. JOURNAL OF BIOCHEMISTRY
- Nuclear Receptors HNF4α and LRH-1 Cooperate in RegulatingCyp7a1 in Vivo
- (2012) Serkan Kir et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease
- (2012) Derrick E. Fouts et al. JOURNAL OF HEPATOLOGY
- FXR signaling in the enterohepatic system
- (2012) Tsutomu Matsubara et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Downregulation of Human Farnesoid X Receptor by miR-421 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells
- (2012) Y. Zhang et al. MOLECULAR CANCER RESEARCH
- Hepatocarcinogenesis in FXR−/−Mice Mimics Human HCC Progression That Operates through HNF1α Regulation of FXR Expression
- (2012) Nian Liu et al. MOLECULAR ENDOCRINOLOGY
- Blueberry Husks and Probiotics Attenuate Colorectal Inflammation and Oncogenesis, and Liver Injuries in Rats Exposed to Cycling DSS-Treatment
- (2012) Åsa Håkansson et al. PLoS One
- Inhibition of Intestinal Bile Acid Transporter Slc10a2 Improves Triglyceride Metabolism and Normalizes Elevated Plasma Glucose Levels in Mice
- (2012) Thomas Lundåsen et al. PLoS One
- Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure
- (2012) Mitsuhiro Watanabe et al. PLoS One
- Obesity and hepatocellular carcinoma: targeting obesity-related inflammation for chemoprevention of liver carcinogenesis
- (2012) Masahito Shimizu et al. Seminars in Immunopathology
- TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
- (2012) Taoufiq Harach et al. Scientific Reports
- Long-term (52–78 weeks) treatment with colesevelam HCl added to metformin therapy in type 2 diabetes mellitus patients
- (2012) Harold Bays Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Bile Acids Induce Inflammatory Genes in Hepatocytes
- (2011) Katryn Allen et al. AMERICAN JOURNAL OF PATHOLOGY
- Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes
- (2011) Lihong Chen et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells
- (2011) Xiaofang Huo et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Fish oil combined with SCFA synergistically prevent tissue accumulation of NEFA during weight loss in obese mice
- (2011) Maiken H. Pedersen et al. BRITISH JOURNAL OF NUTRITION
- Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion
- (2011) HE Parker et al. BRITISH JOURNAL OF PHARMACOLOGY
- Obesity and Type 2 Diabetes: What Can Be Unified and What Needs to Be Individualized?
- (2011) R. H. Eckel et al. DIABETES CARE
- Endotoxemia Is Associated With an Increased Risk of Incident Diabetes
- (2011) P. J. Pussinen et al. DIABETES CARE
- Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: a randomised controlled study
- (2011) C. Beysen et al. DIABETOLOGIA
- TGR5: A Novel Target for Weight Maintenance and Glucose Metabolism
- (2011) Xiaosong Chen et al. Experimental Diabetes Research
- The relationship between gut microbiota and weight gain in humans
- (2011) Emmanouil Angelakis et al. Future Microbiology
- Bile Acid Is a Host Factor That Regulates the Composition of the Cecal Microbiota in Rats
- (2011) K.B.M. Saiful Islam et al. GASTROENTEROLOGY
- Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease
- (2011) R. M. Gadaleta et al. GUT
- The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice
- (2011) Yan-Dong Wang et al. HEPATOLOGY
- Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis
- (2011) Sigurd Lax et al. INTERNATIONAL JOURNAL OF CANCER
- Glucose and Insulin Induction of Bile Acid Synthesis
- (2011) Tiangang Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition by zinc of deoxycholate-induced apoptosis in HCT-116 cells
- (2011) Abigail F. Smith et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Functional characterization of genetic variants in the apical sodium-dependent bile acid transporter (ASBT; SLC10A2)
- (2011) Richard H Ho et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Changes in Gastrointestinal Hormones and Leptin After Roux-en-Y Gastric Bypass Surgery
- (2011) Lauren M. Beckman et al. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
- Increased Activation of the Wnt/ -Catenin Pathway in Spontaneous Hepatocellular Carcinoma Observed in Farnesoid X Receptor Knockout Mice
- (2011) A. Wolfe et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Role of bile salt in regulating Mcl-1 phosphorylation and chemoresistance in hepatocellular carcinoma cells
- (2011) Mingmei Liao et al. Molecular Cancer
- Responses of Gut Microbiota to Diet Composition and Weight Loss in Lean and Obese Mice
- (2011) Yann Ravussin et al. Obesity
- Barcoded Pyrosequencing Reveals That Consumption of Galactooligosaccharides Results in a Highly Specific Bifidogenic Response in Humans
- (2011) Lauren M. G. Davis et al. PLoS One
- The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
- (2011) Sabrina Cipriani et al. PLoS One
- Dose-Response of Five Bile Acids on Serum and Liver Bile Acid Concentrations and Hepatotoxicty in Mice
- (2011) Peizhen Song et al. TOXICOLOGICAL SCIENCES
- Understanding the role of gut microbiome–host metabolic signal disruption in health and disease
- (2011) Elaine Holmes et al. TRENDS IN MICROBIOLOGY
- Colonization-Induced Host-Gut Microbial Metabolic Interaction
- (2011) S. P. Claus et al. mBio
- Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities
- (2010) Rohit Kohli et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The bile acid sensor FXR regulates insulin transcription and secretion
- (2010) Barbara Renga et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Ameliorative effects of konjac glucomannan on human faecal β-glucuronidase activity, secondary bile acid levels and faecal water toxicity towards Caco-2 cells
- (2010) Wen-Tzu Wu et al. BRITISH JOURNAL OF NUTRITION
- Insulin resistance and cancer: Epidemiological evidence
- (2010) Shoichiro Tsugane et al. CANCER SCIENCE
- Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21
- (2010) Wen‑Jie Cai et al. CELL BIOLOGY INTERNATIONAL
- Differential Adaptation of Human Gut Microbiota to Bariatric Surgery-Induced Weight Loss: Links With Metabolic and Low-Grade Inflammation Markers
- (2010) J.-P. Furet et al. DIABETES
- Obesity, Diabetes, and Gut Microbiota: The hygiene hypothesis expanded?
- (2010) G. Musso et al. DIABETES CARE
- Diabetes and Cancer: A consensus report
- (2010) E. Giovannucci et al. DIABETES CARE
- Bile Acids as Regulators of Hepatic Lipid and Glucose Metabolism
- (2010) Michael Trauner et al. DIGESTIVE DISEASES
- The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation
- (2010) Thijs W.H. Pols et al. JOURNAL OF HEPATOLOGY
- Enterobacteria Modulate Intestinal Bile Acid Transport and Homeostasis through Apical Sodium-Dependent Bile Acid Transporter (SLC10A2) Expression
- (2010) M. Miyata et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults
- (2010) Nadja Larsen et al. PLoS One
- Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis
- (2010) Johannes R. Hov et al. PLoS One
- Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
- (2010) B. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Weight and Type 2 Diabetes after Bariatric Surgery: Systematic Review and Meta-analysis
- (2009) Henry Buchwald et al. AMERICAN JOURNAL OF MEDICINE
- Bile Acid-Induced Elevated Oxidative Stress in the Absence of Farnesoid X Receptor
- (2009) Masahiro Nomoto et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
- (2009) Charles Thomas et al. Cell Metabolism
- Obesity and the human microbiome
- (2009) Ruth E Ley CURRENT OPINION IN GASTROENTEROLOGY
- Global estimates of the prevalence of diabetes for 2010 and 2030
- (2009) J.E. Shaw et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Sodium deoxycholate causes nitric oxide mediated DNA damage in oesophageal cells
- (2009) Arthur J. Jolly et al. FREE RADICAL RESEARCH
- High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity
- (2009) Marie A. Hildebrandt et al. GASTROENTEROLOGY
- Long-term Safety and Tolerability of Colesevelam HCl in Subjects with Type 2 Diabetes
- (2009) A. B. Goldfine et al. HORMONE AND METABOLIC RESEARCH
- Effect of a Low Dose of Dietary Resveratrol on Colon Microbiota, Inflammation and Tissue Damage in a DSS-Induced Colitis Rat Model
- (2009) Mar Larrosa et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Bile acids and insulin resistance: implications for treating nonalcoholic fatty liver disease
- (2009) Jue WEI et al. Journal of Digestive Diseases
- The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity
- (2009) P. Vavassori et al. JOURNAL OF IMMUNOLOGY
- FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats
- (2009) Sabrina Cipriani et al. JOURNAL OF LIPID RESEARCH
- Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism
- (2009) Mary-Elizabeth Patti et al. Obesity
- Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
- (2009) Philippe Lefebvre et al. PHYSIOLOGICAL REVIEWS
- A Variant of the SLC10A2 Gene Encoding the Apical Sodium-Dependent Bile Acid Transporter Is a Risk Factor for Gallstone Disease
- (2009) Olga Renner et al. PLoS One
- Human gut microbiota in obesity and after gastric bypass
- (2009) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation
- (2008) Francesco Raimondi et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- TNFα is required for cholestasis-induced liver fibrosis in the mouse
- (2008) Erwin Gäbele et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Obesity and steatosis influence serum and hepatic inflammatory markers in chronic hepatitis C
- (2008) Julie R. Jonsson et al. HEPATOLOGY
- Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response
- (2008) Yan-Dong Wang et al. HEPATOLOGY
- Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation inApcMin/+ colon epithelial cells
- (2008) Jenifer I. Fenton et al. INTERNATIONAL JOURNAL OF CANCER
- Serum leptin, adiponectin, and resistin concentration in colorectal adenoma and carcinoma (CC) patients
- (2008) Anna Kumor et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Human colonic microbiota associated with diet, obesity and weight loss
- (2008) S H Duncan et al. INTERNATIONAL JOURNAL OF OBESITY
- Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure−Activity Relationships, and Molecular Modeling Studies
- (2008) Hiroyuki Sato et al. JOURNAL OF MEDICINAL CHEMISTRY
- The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF- B activation in oesophageal cells, with a mechanism of action involving ROS
- (2008) G. J. S. Jenkins et al. MUTAGENESIS
- A core gut microbiome in obese and lean twins
- (2008) Peter J. Turnbaugh et al. NATURE
- Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
- (2008) H. Sokol et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bile acid transporters in health and disease
- (2008) A. Kosters et al. XENOBIOTICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search