Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer

The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation

(2011) Jingling Jin et al.   HEPATOLOGY

Gankyrin-mediated dedifferentiation facilitates the tumorigenicity of rat hepatocytes and hepatoma cells

(2011) Wen Sun et al.   HEPATOLOGY

Overexpression of a novel gene gankyrin correlates with the malignant phenotype of colorectal cancer

(2010) Shanhong Tang et al.   CANCER BIOLOGY & THERAPY

Gankyrin promotes the proliferation of human pancreatic cancer

(2010) Yun Meng et al.   CANCER LETTERS

Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells

(2010) Jiang-Hong Man et al.   JOURNAL OF CLINICAL INVESTIGATION

Elimination of C/EBPα through the ubiquitin-proteasome system promotes the development of liver cancer in mice

(2010) Guo-Li Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis

(2010) Sayeepriyadarshini Anakk et al.   JOURNAL OF CLINICAL INVESTIGATION

Intracellular signaling and hepatocellular carcinoma

(2010) Polina Iakova et al.   SEMINARS IN CANCER BIOLOGY

Liver Regeneration after Partial Hepatectomy

(2009) George K. Michalopoulos   AMERICAN JOURNAL OF PATHOLOGY

Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine

(2009) Ann M. Thomas et al.   HEPATOLOGY

The Age-Associated Decline of Glycogen Synthase Kinase 3  Plays a Critical Role in the Inhibition of Liver Regeneration

(2009) J. Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

Aging and liver regeneration

(2009) Nikolai A. Timchenko   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hepatocellular carcinoma and the ubiquitin–proteasome system

(2008) Simon P. Dawson   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cellular senescence and organismal aging

(2008) Jessie C. Jeyapalan et al.   MECHANISMS OF AGEING AND DEVELOPMENT