Novel relationships between oxidative stress and angiogenesis-related factors in sepsis: New biomarkers and therapies

The beginning of personalized medicine in sepsis: small steps to a bright future

(2014) E. Christaki et al.   CLINICAL GENETICS

Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour

(2014) Ricard Ferrer et al.   CRITICAL CARE MEDICINE

Biomarcadores en la sepsis. ¿Simplificando lo complejo?

(2014) Cristóbal León et al.   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

Novel approaches to the development of anti-sepsis drugs

(2014) Christian Lehmann et al.   Expert Opinion on Drug Discovery

Oxidative Stress, Prooxidants, and Antioxidants: The Interplay

(2014) Anu Rahal et al.   Biomed Research International

Biomarkers for Sepsis: A Review with Special Attention to India

(2014) George E. Nelson et al.   Biomed Research International

Oxidative stress in angiogenesis and vascular disease

(2013) Y.-W. Kim et al.   BLOOD

Cellular and molecular mechanisms in the hypoxic tissue: role of HIF-1 and ROS

(2013) Andrea B. Zepeda et al.   CELL BIOCHEMISTRY AND FUNCTION

Surviving Sepsis Campaign

(2013) R. Phillip Dellinger et al.   CRITICAL CARE MEDICINE

A Multibiomarker-Based Outcome Risk Stratification Model for Adult Septic Shock*

(2013) Hector R. Wong et al.   CRITICAL CARE MEDICINE

Biomarkers of sepsis

(2013) James D. Faix   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Update on antioxidant micronutrients in the critically ill

(2013) William Manzanares et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Utilidad de los biomarcadores de inflamación e infección en los servicios de urgencias

(2013) Agustín Julián-Jiménez et al.   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

Oxidative status in ICU patients with septic shock

(2013) Maria Karapetsa et al.   FOOD AND CHEMICAL TOXICOLOGY

Reactive Oxygen Species in the Immune System

(2013) Yuhui Yang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis

(2013) Tilman Ziegler et al.   JOURNAL OF CLINICAL INVESTIGATION

Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients

(2013) Glenn Hernandez et al.   JOURNAL OF CRITICAL CARE

Genetic predisposition to acute kidney injury induced by severe sepsis

(2013) Pablo Cardinal-Fernández et al.   JOURNAL OF CRITICAL CARE

A Randomized Trial of Glutamine and Antioxidants in Critically Ill Patients

(2013) Daren Heyland et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Non-Lethal Traumatic/Hemorrhagic Insult Strongly Modulates the Compartment-Specific PAI-1 Response in the Subsequent Polymicrobial Sepsis

(2013) Pierre Raeven et al.   PLoS One

Role of Biomarkers in Sepsis Care

(2013) Ravi S. Samraj et al.   SHOCK

Biomarkers of Endothelial Cell Activation in Early Sepsis

(2013) Simon Skibsted et al.   SHOCK

Biomarkers of endothelial activation/dysfunction in infectious diseases

(2013) Andrea V Page et al.   Virulence

Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock

(2013) Daniel De Backer et al.   Virulence

Biomarkers in Sepsis

(2013) Keith R. Walley   Current Infectious Disease Reports

Role of microparticles in sepsis

(2012) V.L. Reid et al.   BRITISH JOURNAL OF ANAESTHESIA

New Approaches to Sepsis: Molecular Diagnostics and Biomarkers

(2012) K. Reinhart et al.   CLINICAL MICROBIOLOGY REVIEWS

Administration of tetrahydrobiopterin improves the microcirculation and outcome in an ovine model of septic shock*

(2012) Xinrong He et al.   CRITICAL CARE MEDICINE

The Dynamics of Angiogenic Factors and Their Soluble Receptors in Relation to Organ Dysfunction in Disseminated Intravascular Coagulation Associated with Sepsis

(2012) Subrina Jesmin et al.   INFLAMMATION

Vascular endothelial growth factor, as compared with placental growth factor, is increased in severe sepsis but not in organ failure

(2012) D. M. SMADJA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study

(2012) Mitchell M Levy et al.   LANCET INFECTIOUS DISEASES

Lung Oxidative Damage by Hypoxia

(2012) O. F. Araneda et al.   Oxidative Medicine and Cellular Longevity

High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study

(2012) Sisse R Ostrowski et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

Does lactate measurement performed on admission predict clinical outcome on the intensive care unit? A concise systematic review

(2012) H.-A. Borthwick et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Biomarkers of endothelial dysfunction: can they help us deciphering systemic inflammation and sepsis?

(2011) Patrick Paulus et al.   BIOMARKERS

Oxidative stress and mitochondrial dysfunction in sepsis

(2011) H.F. Galley   BRITISH JOURNAL OF ANAESTHESIA

Effect of a mitochondria-targeted vitamin E derivative on mitochondrial alteration and systemic oxidative stress in mice

(2011) Gaowei Mao et al.   BRITISH JOURNAL OF NUTRITION

Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis*

(2011) Daniel R. Ricciuto et al.   CRITICAL CARE MEDICINE

The Effects of Sepsis on Mitochondria

(2011) Glòria Garrabou et al.   JOURNAL OF INFECTIOUS DISEASES

Plasma Biomarkers of Oxidant Stress and Development of Organ Failure in Severe Sepsis

(2011) Lorraine B. Ware et al.   SHOCK

Endothelial Cell Activation in Emergency Department Patients with Sepsis-Related and Non-Sepsis-Related Hypotension

(2011) Philipp Schuetz et al.   SHOCK

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Sepsis-associated encephalopathy and its differential diagnosis

(2010) Emanuele Iacobone et al.   CRITICAL CARE MEDICINE

Effects of fluids on microvascular perfusion in patients with severe sepsis

(2010) Gustavo Ospina-Tascon et al.   INTENSIVE CARE MEDICINE

Oxidative stress in critical care medicine

(2010) M. E. Bernal et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Oxidative stress as a novel target in pediatric sepsis management

(2010) Bettina von Dessauer et al.   JOURNAL OF CRITICAL CARE

Increased myeloperoxidase enzyme activity in plasma is an indicator of inflammation and onset of sepsis

(2010) Nikhil Kothari et al.   JOURNAL OF CRITICAL CARE

Biomarker discovery and development in pediatric critical care medicine*

(2010) Jennifer M. Kaplan et al.   Pediatric Critical Care Medicine

Vascular Endothelial Growth Factor in Severe Sepsis and Septic Shock

(2009) Sari Karlsson et al.   ANESTHESIA AND ANALGESIA

Septic impairment of capillary blood flow requires nicotinamide adenine dinucleotide phosphate oxidase but not nitric oxide synthase and is rapidly reversed by ascorbate through an endothelial nitric oxide synthase-dependent mechanism*

(2009) Karel Tyml et al.   CRITICAL CARE MEDICINE

Selenoprotein P, Rather than Glutathione Peroxidase, as a Potential Marker of Septic Shock and Related Syndromes

(2009) X. Forceville et al.   EUROPEAN SURGICAL RESEARCH

Mitochondrial Nitric Oxide Synthase: A Masterpiece of Metabolic Adaptation, Cell Growth, Transformation, and Death

(2009) Paola V. Finocchietto et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The microcirculation as a diagnostic and therapeutic target in sepsis

(2009) Andrea Nencioni et al.   Internal and Emergency Medicine

ANGIOPOIETIN-1 IN THE TREATMENT OF ISCHEMIA AND SEPSIS

(2009) Nathan M. Novotny et al.   SHOCK

VARIABLE EFFECTS OF INHIBITING iNOS AND CLOSING THE VASCULAR ATP-SENSITIVE POTASSIUM CHANNEL (VIA ITS PORE-FORMING AND SULFONYLUREA RECEPTOR SUBUNITS) IN ENDOTOXIC SHOCK

(2009) Alastair O'Brien et al.   SHOCK

Multiple Organ Dysfunction Syndrome in Critical Surgical Illness

(2009) Philip S. Barie et al.   Surgical Infections

Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury

(2008) Qiang Li et al.   BIOCHEMICAL JOURNAL

The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide–peptidoglycan model of sepsis

(2008) Damon A. Lowes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Elevated levels of placental growth factor represent an adaptive host response in sepsis

(2008) Kiichiro Yano et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Retinoic acid dampens LPS-induced NF-κB activity: results from human monoblasts and in vivo imaging of NF-κB reporter mice

(2008) Liv M. Austenaa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Clinical sepsis and septic shock—definition, diagnosis and management principles

(2008) Jean-Louis Vincent   LANGENBECKS ARCHIVES OF SURGERY